Streptomyces sp. S1D4-11: HEP87_39335
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Entry
HEP87_39335 CDS
T10399
Symbol
cyc2
Name
(GenBank) germacradienol/geosmin synthase Cyc2
KO
K10187
germacradienol/geosmin synthase [EC:
4.2.3.22
4.2.3.75
4.1.99.16
]
Organism
stsd Streptomyces sp. S1D4-11
Pathway
stsd00909
Sesquiterpenoid and triterpenoid biosynthesis
stsd01100
Metabolic pathways
stsd01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
stsd00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
HEP87_39335 (cyc2)
Enzymes [BR:
stsd01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.99 Other carbon-carbon lyases
4.1.99.16 geosmin synthase
HEP87_39335 (cyc2)
4.2 Carbon-oxygen lyases
4.2.3 Acting on phosphates
4.2.3.22 germacradienol synthase
HEP87_39335 (cyc2)
4.2.3.75 (-)-germacrene D synthase
HEP87_39335 (cyc2)
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Gene cluster
GFIT
Motif
Pfam:
Terpene_syn_C_2
Motif
Other DBs
NCBI-ProteinID:
XES00874
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Position
8645403..8647748
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AA seq
781 aa
AA seq
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MTQPFELPHFYMPYPARLNPHLDEARAHTVEWARGMGMLEGSGIWEQSDLDAHDYGLLCA
YTHPDCDGPALSLITDWYVWVFFFDDHFLETFKRTQDRDGGKAYLDRLPLFMPLDLSTPV
PEPENPVEAGLADLWARTVPAMSVDWRGRFAVSTEHLLNESMWELSNINEGRIANPVEYI
EMRRKVGGAPWSAGLVEYATAEVPASVAGTRPLRVLMETFSDGVHLRNDLFSYQREVEVE
GELSNGILVLETFFGCTTQEAAETVNDILTSRLHQFEHTALTEVPALAAEKGLTPDQVAA
VAAYTQGLQDWQSGGHEWHLRSSRYMNEGAVEGSRPFGLAELGTSAVDIGALLSAAGAER
LRRYTHVPYQKVGPSLLPDFSMPFELALSPHLDGARDRLTGWMYEKGMLQEGVWDEDKLV
AYDLPLCAAGIHPDATEEALDLGSQWLAWGTYGDDYYPLVFGHRRDLAAAKATTERLSAC
MPIEGEPTPVPANAMEHGLLDLWERTTAKMTPDERRKLRGDVDKMTESWVWELSNQLQHR
IPDPIDYLEMRRATFGSDLTLNLCRLGHGPKVPPEVYRSGPVRSLENAASDYAMLINDVF
SYQKEIEYEGEVHNAILVVQNFFGCDYPTGLGIIHDLMTQRMQQFQHVVAYELPLLYEDF
KLSQEVRGIMDGYVVQLENWLSGILKWHQDCHRYGAEDLARRAHGFLPDRAPTVPFPGTG
VGTVPEPEPVLSPHDMEETEAPPDLTPRIAAGATPSFTLPKGVGAAAEFSLPRAEATSAP
H
NT seq
2346 nt
NT seq
+upstream
nt +downstream
nt
atgacgcagccgttcgaactcccgcacttctacatgccgtatcccgcgcggttgaacccg
cacctcgacgaggcgcgcgcccacacggtcgaatgggcccgtgggatgggcatgttggag
ggctccggcatctgggaacagtccgacctcgacgcgcacgactacgggctgctctgtgcg
tacacccaccccgactgcgacggcccggcactctcgctcatcaccgactggtacgtgtgg
gtcttcttcttcgacgaccacttcctggagaccttcaaacgcacccaggaccgcgacggc
ggcaaggcctatctggaccggctgcccctcttcatgccgctggacctctcgacccccgta
ccggagccggagaatccggtcgaggcagggctcgccgacctctgggcgcgcacggtgccc
gcgatgtcggtggactggcgggggcggttcgcggtgtccacggagcacctgctcaacgag
tcgatgtgggagctctccaacatcaacgaggggcggatcgccaaccccgtcgagtacatc
gagatgcgccgcaaggtgggcggcgccccctggtcggcggggctcgtggagtacgcgacg
gccgaggtgcccgcctccgtcgcggggacgcgcccgctgcgggtgctgatggagacgttc
tcggacggggtccatctgcgcaatgacctgttctcctaccagcgcgaggtcgaggtcgag
ggcgagctcagcaacggcatcctcgtcctggagaccttcttcggctgcaccacccaggag
gccgccgagaccgtcaacgacatcctcacctcacgcctgcaccagttcgagcacacggcc
ctcaccgaagtgcccgcactcgccgcggagaagggactcaccccggaccaggtcgccgcc
gtcgccgcgtacacccaggggctccaggactggcagtcgggcggccacgagtggcacctg
cgctccagccgctacatgaacgagggggcggtggagggcagtcggccgttcggtctcgcc
gagctcggcacctcggccgtcgacatcggcgcactgctctccgcggccggggcggagcgg
ctgcgcaggtacacccatgtcccgtaccagaaggtcggcccgtccctgctccccgacttc
tccatgcccttcgagctcgccctcagcccccacctggacggcgcccgcgaccgcctcacc
ggctggatgtacgagaagggcatgctccaggagggcgtctgggacgaggacaagctggtg
gcgtacgaccttccgctgtgcgccgcgggcatccacccggacgcgaccgaggaagccctc
gacctcggctcccagtggctggcctgggggacgtacggcgacgattactacccgctggtc
ttcggacaccgccgtgacctggcggcggcgaaggcgaccaccgaacgcctctcggcctgc
atgcccatcgagggcgagccgacgccggtcccggccaacgccatggagcacggcctcctc
gacctgtgggagcgcacgacggcgaagatgacgccggacgagcggcgcaagctgcgcggc
gacgtggacaagatgacggagagctgggtgtgggagctgtcgaaccagctccagcaccgg
atccccgacccgatcgactacctggagatgcgccgcgccaccttcggctccgacctcacc
ctgaacctgtgccgcctgggccacggccccaaggtcccgccggaggtctaccggagcggt
cccgtccggtcgttggagaacgccgccagcgactacgcgatgctcatcaacgacgtcttc
tcgtaccagaaggagatcgagtacgagggcgaggtccacaacgccatcctcgtcgtgcag
aacttcttcggctgcgactacccgaccggcctcggcatcatccatgacctgatgacccag
cgcatgcagcagttccagcacgtcgtcgcctatgaactgccgctcctgtacgaggacttc
aagctctcgcaggaggtgcgcgggatcatggacggctatgtggtgcaactcgagaactgg
ctctccggaatcctgaaatggcaccaggactgccaccgttacggcgccgaggacctggcc
cgccgggcccacggcttcctgccggaccgggctcccacggtgccgttccccgggacgggg
gtcgggaccgtaccggagccggagccggtgctcagtccgcacgacatggaggagacggaa
gccccgccggacctgactccccggatcgcagcaggcgccaccccgtcgttcaccctgccg
aagggagtgggagccgccgcggagttcagcctgccgagggccgaggcgacgtccgctccg
cactga
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