Streptomyces qaidamensis: A4E84_28450
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Entry
A4E84_28450 CDS
T04777
Name
(GenBank) isopropylmalate isomerase
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
stsi
Streptomyces qaidamensis
Pathway
stsi00290
Valine, leucine and isoleucine biosynthesis
stsi00660
C5-Branched dibasic acid metabolism
stsi01100
Metabolic pathways
stsi01110
Biosynthesis of secondary metabolites
stsi01210
2-Oxocarboxylic acid metabolism
stsi01230
Biosynthesis of amino acids
Module
stsi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stsi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
A4E84_28450
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
A4E84_28450
Enzymes [BR:
stsi01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
A4E84_28450
4.2.1.35 (R)-2-methylmalate dehydratase
A4E84_28450
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AMW13076
UniProt:
A0A143C6F4
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All DBs
Position
6379730..6381160
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKTGRTVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNAADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPMSRPKTMAITVDGELPEGVTA
KDLILAIIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRPHAPEGADWDAAVAYWKTLKTDDDAEFDAEVVIDASALSPFVTWGTNPGQGAPL
SASVPDPASYEDASERYAAEKALEYMGLEAGQPLRSITVDTVFVGSCTNGRIEDLRAAAE
LLKDRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKQAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLADADAPTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaagtctgggacgaccatgtcgtccggcgcgcggagggc
gagcccgaccttctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcg
ttcgacggtctgcgcaagaccggccggaccgtgcggcggctggacctcaccatcgcgacc
gaggaccacaacaccccgaccctggacatcgacaagccgatcgcggacccggtctcgcgg
gtgcagctggagacgctgcgcaagaacgccgccgacttcggtgtgcgtctgcatccgctg
ggcgatgtcgagcagggtgtcgtgcacgtggtgggtccgcagctgggtctgacgcagccg
ggcaccaccgtcgtgtgcggtgactcccacacctccacgcacggtgctttcggtgcgctg
gcgttcggtatcggcacctcccaggtggagcatgtgctggccacccagacgctgccgatg
tcccgcccgaagaccatggcgatcacggtcgacggtgaactgcccgagggtgtcacggcc
aaggacctgatcctggcgatcatcgcgaagatcggcacgggcggcgggcagggctatgtc
ctggagtaccgcggcgaggccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgccccggacgaaacgacgttc
gcctacctcaagggccgcccgcacgcccccgagggcgccgactgggacgcggccgtcgcg
tactggaagacgctgaagacggacgacgacgccgagttcgatgccgaggtcgtcatcgat
gcctccgcgctgtcgccgttcgtcacctggggtaccaaccccgggcagggcgcaccgctt
tcggcgtccgtccccgatcctgcttcgtacgaagacgcatcggagcgctacgccgccgaa
aaggccctggagtacatggggttggaggccgggcagccgctgcgttccatcacggtggac
accgtcttcgtaggctcctgcaccaacggccgtatcgaggacctgcgtgccgcggccgag
ctgctcaaggaccgcaaagtcgccgacggcgtacggatgctggtcgtccccggttcggcg
cgggtgggtctgcaggccgtctccgaggggctggacgtcgtcttcaagcaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgaggggcggcagggcaagggcggc
cgcacccacctggtgtcgccgcaggtcgccgccgccaccgccgtcctgggccacctggcc
tccccggccgacctggccgacgccgacgcccccacgcccgctggagtctga
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