Streptomyces tsukubensis: B7R87_07020
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Entry
B7R87_07020 CDS
T07155
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stsu
Streptomyces tsukubensis
Pathway
stsu00300
Lysine biosynthesis
stsu00550
Peptidoglycan biosynthesis
stsu01100
Metabolic pathways
stsu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stsu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
B7R87_07020
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
B7R87_07020
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
B7R87_07020
Enzymes [BR:
stsu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
B7R87_07020
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2065
Motif
Other DBs
NCBI-ProteinID:
AZK93652
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Position
complement(1880874..1882304)
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AA seq
476 aa
AA seq
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MITLSLTEIAAVVGGQPYDIPDPDRTVTGPVVIDSRAVVPGALFAAFAGASADGHDYAAR
AVADGACAVLATRPVGVPAIVVPDVTAALGALARHVVESLGATTVALTGSVGKTGTKDLI
AQLLARKGPTIYPEGNLNNEIGLPLTALRADTTTEHLVLEMGARYVGDIRYLTELVPPRI
SVVLNVGTAHIGEFGGREKIAEAKGEIVEALPADGVAVLNADDPLVRAMADRTRARVVFF
GESPNAAVRAENVRLTRQGRPAFTLHTPTGCGEVTMRLYGEHHVSNALAAAAVAHELGMP
VSEIAGALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGQDAQSRG
GRTWAVLGLMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAADLLRSELRPGDVVLVKASRSAGLERLAQTLIDDAAVAADGRGAGR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaccctctccctcaccgagatcgccgcagtcgtcggcgggcagccgtacgacata
ccggatccggaccgcacggtcaccgggcccgtcgtgatcgactcccgggccgtcgtcccc
ggcgccctgttcgccgccttcgcgggcgccagcgcggacggccacgactacgcagcccgg
gccgtcgccgacggcgcctgcgccgtcctggcgacccggcccgtcggcgtacccgcgatc
gtggtgcccgatgtcaccgccgcgctgggcgccctcgcccgccatgtcgtcgaaagcctc
ggcgccaccaccgtcgcgctcaccggctccgtcggcaagaccggcaccaaggacctgatc
gcccagctcctggcgcgcaagggccccacgatctacccggagggcaatctcaacaacgag
atcggcctgccgctgaccgcgctccgcgccgacaccaccaccgaacacctcgtcctggag
atgggcgcccggtacgtcggcgacatccgctatctgaccgaactcgtgccgccgcggatc
tccgtcgtcctgaacgtcggcaccgcccatatcggcgagttcggcggccgcgagaagatc
gcggaagccaagggcgagatcgtggaggccctgcccgccgacggagtcgccgtactcaac
gccgacgaccccctcgtccgggccatggccgaccgcacccgcgcccgcgtcgtgttcttc
ggagagtctccgaacgccgccgtccgtgccgaaaatgtccggctcacccggcaaggtcgg
cccgccttcacgcttcacacccccaccgggtgcggcgaagtgaccatgcggctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgccc
gtctccgagatcgccggcgcgctctccgaggccggcaccctctcccgctggcgcatggag
gtcaccgagcgaccggacggcgtgacgatcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgggcggcgctgcgcgccctggccgccatgggacaggacgcacagagccggggg
ggacggacatgggcggtgctcggtctcatggcggagctcggtgacgaggcgctcgccgag
cacgacgccgtcggacggctcgccgtccggctcaacgtcagcaagctcgttgcagtcggg
ggcagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcggccgacctgttgcgcagtgagctgcgccca
ggagacgtcgtgctggtgaaggcgtccagatctgccggtctggaacggctcgcgcagacg
ctgattgacgacgcggcggtggccgcggacgggcggggtgccggtcgatga
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