Salmonella enterica subsp. enterica serovar Typhi Ty2: t0291
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Entry
t0291 CDS
T00121
Symbol
purL
Name
(GenBank) phosphoribosylformylglycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
stt
Salmonella enterica subsp. enterica serovar Typhi Ty2
Pathway
stt00230
Purine metabolism
stt01100
Metabolic pathways
stt01110
Biosynthesis of secondary metabolites
Module
stt_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
stt00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
t0291 (purL)
Enzymes [BR:
stt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
t0291 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AAO68016
UniProt:
Q8Z4L6
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All DBs
Position
328621..332508
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AA seq
1295 aa
AA seq
DB search
MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQ
YGPALSSHTLAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQIDRLERGVAYYIEASTLT
AEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGL
ALAEDEIDYLQEAFTKLGCNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKM
IKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVNRVLHLPTVAEKTFLVTIGDRTV
TGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMS
MKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAMQVLVAARKLLAWHDRSDGGLLVTLAEMAFA
GHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVETLLAQYGLADCVHYLGQALA
GDRFVITANDRTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPGLNVK
LSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRI
GLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPH
PERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtctgcattccgtatcaataaactgctg
gcgcgctttcaggctgccaacctccaggtccacaatatatacgctgagtatgtccatttt
gctgacctgaacgccccgttaaatgatagcgagcaggcgcagcttacccgtctgctgcaa
tacggcccggcgcttagcagccatacgctggcgggtaaactcctgttggtcacaccgcgt
cctggtaccatctccccctggtcttcaaaagcaacggatatcgcccacaactgcggcctg
caacagattgaccgtctggagcgcggcgtagcgtactatatcgaggcttcgacgttgacg
gcggaacagtggcgacaagtggccgcagagctgcacgaccgtatgatggagacggtgttc
tcttctttaaccgatgcggaaaaactgtttatccaccatcagcctgcgccggtttccagt
gtcgatctgctgggagaaggccgtcaggcgttaattgacgctaacctgcgtctcggtctg
gcgctggcggaagatgaaatcgactatttgcaggaggcgtttaccaaactgggatgcaac
ccgaacgatatcgaactgtacatgttcgcccaggcgaactccgagcactgccgccacaag
atttttaacgccgactggattatcgacggtaaaccgcagccgaagtcgctgtttaaaatg
attaaaaacaccttcgaaaccacgccggactatgtgctctctgcctataaagacaatgcc
gcggtgatggaaggatctgcggtggggcgctacttcgccgaccacaataccggccgttac
gattttcatcaggagcccgcgcacattctgatgaaggtcgaaacgcataaccacccaacc
gccatctctccgtggccgggggcggcgaccggttccggcggcgaaattcgtgatgaaggc
gccaccgggcgtggcgcgaaaccaaaagccgggctggtaggcttctccgtttccaacctg
cgtattccgggctttgaacagccgtgggaagaggattttggcaagccggaacgtattgtc
accgcgctggatatcatgaccgaaggtccgctgggcggcgcggcgtttaacaacgaattt
ggtcgcccggcgctgaccggttacttccgtacttatgaagagaaagtgaacagccacaat
ggcgaagagctgcgtggctatcacaagccgatcatgctggcgggcgggatcggtaatatc
cgcgccgatcacgtgcagaaaggcgagatcgtcgtaggcgcgaagctgatcgtccttggc
ggcccggcgatgaatatcggcctcggcggcggcgcggcatcgtcaatggcttccggccag
tctgatgcggatctcgattttgcctctgttcagcgcgacaacccggaaatggaacgccgc
tgccaggaagtgatcgaccgctgctggcagttgggcgacgctaacccaatcctgtttatc
catgatgtgggcgcgggcggtctctccaacgccatgccggagctggtaagcgacggcggg
cgcggcgggaaattcgaactgcgcgacattcttagcgacgagccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggagcgctatgtgctggcggtcgcggctgaccagtta
ccgctgttcgatgaactgtgtaagcgcgaacgcgcgccgtatgcggtcattggcgacgct
accgaagaacagcatctctcgttgcatgataaccatttcgacaatcagccgatcgatcta
ccgctggatgtcctgctgggcaaaacaccgaaaatgacccgcgatgtgcaaacattgaag
gcgaaaggcgatgcgctgaaccgcgcggatatcacgattgccgacgcggtaaatcgtgtt
ctgcatctgccgaccgtggcggaaaaaaccttccttgtcactattggcgaccgtaccgtc
accggtatggtggcgcgtgaccagatggttggcccgtggcaggtcccggtagctgactgc
gcggtcactaccgctagcctcgacagctactacggcgaagcgatgtcgattggcgagcgc
gcgccggtggcgctgctggactttgccgcctccgcccgtctggccgtcggtgaagcgttg
actaacattgccgcgacgcagattggcgatatcaagcgcattaagctttccgctaactgg
atggcggcagccggtcatcctggcgaagatgccggtttgtatgacgcggttaaagcggtg
ggagaggaactctgtccgcagcttggcctgacgattccggtgggtaaagattcgatgtcg
atgaaaacccgctggcaggaaggcaacgaacagcgcgaaatgacctcgccgctgtcgctg
gtgatttccgcgtttgcccgcgtggaagacgtgcgtcacacccttacgccgcagctgtca
acggaagataacgccttgctgctgatcgatcttggcaagggccacaacgcgctgggcgca
acggcgttggcgcaggtctatcgtcagcttggcgacaaacccgcggacgtgcgtgacgtt
gcgcaactgaaaggcttctatgacgccatgcaggtgctggttgctgcgcgtaaattactg
gcatggcacgaccgttccgacggcggtctgctggtgacgctggccgagatggcctttgcc
ggccactgcggcgtgcaggtcgatatcgccgcgctgggcgatgaccatctggccgcactg
ttcaacgaggagctgggcggcgtgattcaggtacgcgctgaagacagagacgcggtcgaa
acgctgttggcgcagtacggtcttgctgactgcgtccactaccttggtcaggccctggct
ggcgatcgctttgtgattaccgctaatgatcggacggtattcagcgaaagccgtactacg
ctgcgtgtctggtgggcggaaaccacctggcagatgcagcgtctgcgcgacaatccgcaa
tgtgctgaccaggaacacgaggcgaaagcgaatgatgccgatccgggcctcaacgtgaag
ctgtcgtttgatattaatgaagatatcgccgcgccgtacattgcgacaggcgcacgaccg
aaagtcgctgtactgcgcgagcagggggtgaactctcacgtggagatggcggcggcgttc
catcgtgcgggctttgacgcgattgacgtccatatgagcgacctgctgggcggtcgtatc
ggtctgggcaacttccatgcgctggtggcttgcggcggcttttcctacggcgacgtgctg
ggggcgggcgaaggctgggcgaaatccattctgtttaaccatcgggtgcgcgacgaattc
gaaaccttcttccatcgtccgcagacgctggcgctgggcgtgtgcaacggttgccagatg
atgtcgaatctgcgcgagctgatcccgggcagcgaactgtggccgcgttttgtacgtaac
cattctgaccgcttcgaagcccgcttcagcctggtggaagtgacgcaaagcccatcgctg
ctgctgcaaggaatggtaggctcacagatgccgattgcggtttcccatggggaagggcgc
gttgaggtgcgtgacgatgcgcatcttgccgcgcttgagagcaaaggcctggtcgctctg
cgctacgttgataactttggtaaggtgaccgaaacctatccggctaacccgaacggttcg
ccgaacggcatcacggcggtgacgaccgaaaacggtcgggtgacgattatgatgccgcat
ccggaacgcgtattccgcaccgtcgccaactcctggcacccggaaaactggggcgaggat
agcccgtggatgcgtatcttccgtaatgcgcgtaagcagcttggttaa
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