Streptomyces sp. TN58: BSL84_09130
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Entry
BSL84_09130 CDS
T09761
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sttn
Streptomyces sp. TN58
Pathway
sttn00300
Lysine biosynthesis
sttn00550
Peptidoglycan biosynthesis
sttn01100
Metabolic pathways
sttn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sttn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BSL84_09130
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BSL84_09130
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BSL84_09130
Enzymes [BR:
sttn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BSL84_09130
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
APU39912
UniProt:
A0A1L7GD56
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All DBs
Position
complement(2011298..2012728)
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AA seq
476 aa
AA seq
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MIALSLAEIADITGGRPHDIPDPSLQVTGPVVYDSREVRPGSLFAAFVGERVDGHDYAEG
AVAAGAVGVLATRPVGVPAIVVPDVVAALGALARAVVGRLGTDVVALTGSAGKTSTKDLI
AQVLQHHAPTVWTPGNLNNEIGLPITTLRVTEDTQHLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPAEAEGGVAILNADDLLVRSMAGRTKART
VLFGEADDAEIRATEVRMTDRGQPSFTLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHVL
GMSALEIATALSEAGTLSRWRMEVTERADGVTIVNDAYNANPESMRAALRALAAMGGGGR
ANGGRTWAVLGPMAELGDDALAEHDAVGRLVVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVLVSDAQAAVDLLRSELRPGDVVLVKASRSAGLERVAQALLEGTVEGEVAGR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctttccctcgccgagatcgccgacatcaccggcgggcggccccacgacata
ccggatccgtccctccaggtcaccggtcccgtcgtctacgactcccgcgaggtccggccc
ggaagcctgttcgcggccttcgtcggcgaacgggtcgacggccacgactacgccgaaggc
gccgtcgccgccggcgccgtcggcgtcctcgcgacccggcccgtaggcgtccccgccatc
gtcgtccccgacgtggtggcggccctcggtgcgctcgcccgcgccgtcgtcggccgcctc
ggcaccgacgtcgtcgccctcaccgggtccgccggcaagacctccaccaaggacctcatc
gcgcaggtgctccagcaccacgcccccaccgtgtggacccccgggaacctcaacaacgag
atcggcctgccgatcacgacgctgcgcgtcaccgaggacacccagcacctcgtcctggag
atgggcgcccgcggcatcggccacatccgctacctcaccgggctgacgcctcctcggatc
ggcctggtcctcaacgtcggcaccgcgcacatcggggagttcggcggccgcgagcagatc
gcgcaggccaagggcgagctcgtcgaggccctgccggccgaggcggagggcggcgtcgcc
atcctcaacgccgacgacctgctggttcgttccatggccgggcgtacgaaggcccgtacg
gtgctgttcggcgaggccgacgacgccgaaatccgggccacggaagtccgcatgacggac
agggggcagccttccttcacactgcacacaccgaccgggtgcagcgacgtgaccttgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgtcctg
ggcatgtccgccctggagatcgccaccgcgctctccgaagcgggcacgctgtcgcggtgg
cggatggaggtcaccgagcgcgcggacggtgtgacgatcgtcaacgacgcctacaacgcg
aacccggagtccatgcgggccgcactgcgcgcgctcgccgcgatgggcggtggcggcagg
gcgaacggggggcggacgtgggcggtgctcggcccgatggccgagctcggggacgacgct
ctcgccgagcacgacgcggtcggacggcttgtcgtccggctcaacgtgagcaagctcgtc
gcggtcgggggcagggaagcctcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgctcgtgtccgacgcgcaggcggcggtcgacctgttgcgcagtgaa
ctgcgcccgggtgacgtcgtgctggtgaaggcttccaggtcggccggtctggagcgggtg
gcgcaggccctgctcgaaggcactgtcgagggcgaggtcgccggccgatga
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