Streptococcus thermophilus JIM 8232: STH8232_0049
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Entry
STH8232_0049 CDS
T02026
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase II (FGAM synthetase)
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
stu
Streptococcus thermophilus JIM 8232
Pathway
stu00230
Purine metabolism
stu01100
Metabolic pathways
stu01110
Biosynthesis of secondary metabolites
Module
stu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
stu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
STH8232_0049 (purL)
Enzymes [BR:
stu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
STH8232_0049 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
DJ-1_PfpI
GATase
FGAR-AT_PurM_N-like
Motif
Other DBs
NCBI-ProteinID:
CCC18845
LinkDB
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Position
33835..37560
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AA seq
1241 aa
AA seq
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MDKRIFVEKKADFRVKSRSLLKELQHNIQLKTLNDLRIVQVYDVFNLAEDLFARAEKYIF
SEQVTDTVLDEATVKTDLEKYAFFAIESLPGQFDQRAASSQEALLLLGSSSDVTVNTAQL
YLVNKDIAANELEAVKNYLLNPVDSRFKDITVGIAKQDFSESDKTIPNLDFFETYTAEDF
AQYKADQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKNIDF
SASKFQKQLQATYDKYIAMRDELGRAEKPQTLMDMATIFGRYERANGRLDDMEVSDEINA
CSVEIEVDVNGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITTPIAETRAGKLPQQVISKKAAHGYSSYGNQIGLATTYVREYFHPGFVAKRME
LGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGIGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRNGEVTRLIKKSNDFGAGGVCVAIGELADGLEIDLDKVPLKYQGLNG
TEIAISESQERMAVVVRPEDVDIFVAECNKENIDAVVVATVTEKPNLVMHWNGKTIVDLE
RRFLDTNGVRTVVDVKVVDKDVKLPEERKTSAETLEADTLEVLADLNHASQKGLQTMFDS
SVGRSTVNHPLGGRYQITPTEASVQKLPVQYGVTTTASVIAQGFNPYIAEWSPYHGAAYA
VIEATARLVAVGANWSKARFSYQEYFERMDKKAERFGKPVSALLGSIEAQIQLGLPSIGG
KDSMSGTFEELTVPPTLVAFGVTTADSRKVLSPEFKAAGENIYYIPGQALAQEIDFDLIK
SNFAQFEAIQADHKVTAASAVKYGGVIEALALATFGNHIGATVTLENLETALTAQLGGFI
FTSPEEIASVGKIGQTVADFTLAVNGVTLDGYKLDSAFQGKLEEVYPTEFAQATELEEVP
AVTSDTVIKAKEVVEKPVVYIPVFPGTNSEYDSAKAFEKEGAKVNLVPFVTLNEEAIVKS
VDTMVDNIEKANIIFLAGGFSAADEPDGAAKFIVNILLNEKVRAAIDSFIERGGLIIGIC
NGFQALVKSGLLPYGNFEDASSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVKVGDI
HTIPVSHGEGKFVVTTEEFAELRDNGQIFSQYVDFEGKPSMDSKYNPNGSVNAIEGITSK
NGQIIGKMGHSERFEDGLFKNIPGNKEQHLFASAVKYFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggataaacgtattttcgttgagaaaaaagctgattttcgtgtgaaatctcgctcttta
ttaaaagaattacagcataatattcagttgaaaaccttgaatgatcttcgtattgtacaa
gtttacgatgtctttaatttggcagaggatttgtttgcccgtgcggaaaaatatatcttt
tctgagcaagtgaccgatactgttttggatgaagctacagttaagactgaccttgagaag
tatgctttctttgctatcgaaagcttgcctggtcaatttgatcaacgtgcagcatcttca
caagaagctttgcttttgcttggtagctcaagtgatgtaacggttaatactgctcaattg
tacttggttaacaaggacattgctgctaatgaattggaagctgttaaaaattatctattg
aacccagtggactctcgtttcaaagatatcactgttggtattgctaaacaggatttctct
gagtctgacaaaacgattccaaacttggatttctttgaaacttatacagcagaagatttt
gcacagtataaggcagatcaaggattggccatggaagtggatgacctgctcttcattcaa
gattacttcaagtcaattggacgtgtgccaactgagactgaacttaaggttttggatact
tactggtctgaccactgccgccacacaactttcgagactgagttgaaaaacatcgacttc
tcagcttctaaattccaaaaacaattgcaagcaacttatgacaaatatattgccatgcgt
gatgagttgggacgtgcagaaaagcctcaaaccttaatggatatggcgactatttttggt
cgttatgagcgtgccaatggccgtttggatgacatggaagtttctgacgaaatcaatgcc
tgctcagttgaaattgaagtagatgtcaatggtgtcaaagaaccatggcttcttatgttc
aagaacgaaactcataaccacccaacggaaatcgaaccatttggtggagcggctacttgt
atcggtggtgccattcgtgacccattgtcaggtcgttcatacgtttaccaagctatgcgt
atttcaggtgccggtgatattacaacaccaatcgctgaaacacgtgctggaaaattgcca
caacaagtcatttctaaaaaagcggctcatggttattcttcatatggtaaccaaattggt
cttgcaacaacttatgttcgtgaatacttccacccaggtttcgttgccaagcgtatggag
ctaggtgcagttgtcggtgcagctcctaaggagaatgttgtccgtgaaaaacctgaagct
ggagatgtggttatcttgctcggtggtaagactggacgcgacggtatcggtggtgcgaca
ggttcttcaaaagttcaaacggttgaatcagttgaaacagctggtgctgaggttcaaaaa
ggtaatgctatcgaagaacgtaagattcaacgtcttttccgcaatggtgaagtaacacgt
cttatcaagaaatccaatgactttggtgctggtggtgtctgtgtggctatcggtgaattg
gcagatggtcttgaaattgatctagacaaagtgccattgaaataccaaggtttgaacggt
accgaaattgccatctctgaatctcaagaacgtatggctgtggtggttcgtccagaagat
gtagatatcttcgttgctgaatgtaacaaagaaaatattgatgcagttgtcgttgcaacc
gtgactgaaaaaccaaatctcgtcatgcactggaatggtaaaacaattgttgatttggaa
cgtcgtttccttgatacaaatggtgtgcgtacagtagtagatgttaaggtggttgacaag
gatgtcaagcttccagaagaacgcaaaacctctgctgaaacccttgaagcagatacgctt
gaagttttggctgaccttaaccatgcaagtcaaaaaggtttacaaactatgtttgatagc
tcggttggtcgttcaacagtcaatcacccacttggtggtcgataccaaattactccaact
gaagcttctgttcagaaattgccagtccaatatggcgtgacaacaactgcctctgtcata
gcccaaggatttaacccatacatcgcagaatggtctccatatcatggtgctgcatatgca
gtcatcgaagcaacagctcgtttggttgctgttggtgcaaattggtctaaggctcgtttc
tcttatcaagaatacttcgagcgtatggataaaaaagcagagcgttttggtaaaccagta
tcagctcttcttggatcaatcgaagctcagattcaacttggtttgccatctattggtggt
aaggactctatgtcaggcacctttgaagaattgacagtaccaccaaccttggttgctttt
ggggtgacaacagcagacagtcgtaaggtcctttctccagaatttaaggctgctggtgaa
aatatctactacatcccaggtcaagctttggcccaagagattgattttgatctcatcaag
tctaactttgctcagtttgaagctatccaagctgatcacaaagtgacagctgcatcagct
gtcaaatatggtggtgtcattgaagctcttgcacttgcaacgtttgggaaccatatcggg
gcgactgtaacccttgaaaatcttgagactgccttaacagctcaattgggaggattcatc
ttcacatctccggaagagattgcaagtgttggcaagattggacaaacagtagctgacttt
acacttgctgtcaacggtgtaacgcttgatggatataaacttgacagtgcctttcaaggt
aaattggaagaggtttacccaactgaatttgcacaagcaactgagttagaagaagtacct
gctgtgacatcagatactgttataaaagctaaagaagtagttgagaaaccagtggtttac
atcccagtattcccaggtactaactctgagtatgactctgctaaggcctttgaaaaagaa
ggtgccaaagtcaacttagtaccatttgtaacattgaatgaagaagcgattgtcaagtct
gttgacaccatggttgacaatattgaaaaagctaacattatcttccttgcaggtggcttc
tcagcagcggatgaaccagatggagcagctaaatttatcgttaacatcttgctcaatgaa
aaagtacgtgcagctattgatagcttcatcgaacgtggtggtttaatcatcggtatctgt
aacgggttccaagctcttgtcaaatcaggtctccttccatacggtaactttgaagatgca
agcagtactagtccaaccctcttctacaatgatgccaaccaacacgtggctaagatggtt
gaaacacgtattgccaatactaactcaccttggcttgctggagtgaaagttggtgacatc
cataccatcccagtatcacacggtgaaggtaaatttgtcgtgacgactgaagaatttgcg
gagcttcgcgataatggtcaaatctttagccaatatgttgacttcgaaggcaaacctagc
atggattctaaatataatccaaatggttctgtcaatgctattgaaggtatcacaagcaag
aacggtcaaattattggtaagatgggacactcagaacgtttcgaagatggtctcttcaaa
aatattccaggaaataaagaacagcacctatttgcgtcagcggttaaatacttcactgga
aaataa
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