Streptococcus thermophilus JIM 8232: STH8232_1636
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Entry
STH8232_1636 CDS
T02026
Symbol
gshAB
Name
(GenBank) glutathione biosynthesis bifunctional protein gshAB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
stu
Streptococcus thermophilus JIM 8232
Pathway
stu00270
Cysteine and methionine metabolism
stu00480
Glutathione metabolism
stu01100
Metabolic pathways
stu01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
STH8232_1636 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
STH8232_1636 (gshAB)
Enzymes [BR:
stu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
STH8232_1636 (gshAB)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
GARS_A
Dala_Dala_lig_C
RimK
ATPgrasp_ST
ATP-grasp_4
Peptidase_C65
Motif
Other DBs
NCBI-ProteinID:
CCC20306
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All DBs
Position
1363200..1365464
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AA seq
754 aa
AA seq
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MTLNQLLQKLEATSPILQANFGIERESLRVDRQGQLVHTPHPSCLGARSFHPYIQTDFCE
FQMELITPVAKSTTEARRFLGAITDVAGRSIATDEVLWPLSMPPRLKAEEIQVAQLENDF
ERHYRNYLAEKYGTKLQAISGIHYNMELGKDLVEALFQESDQTDMIAFKNALYLKLAQNY
LRYRWVITYLFGASPIAEQGFFDQEVPEPVRSFRNSDHGYVNKEEIQVSFVSLEDYVSAI
ETYIEQGDLNAEKEFYSAVRFRGQKVNRSFLDKGITYLEFRNFDLNPFERIGISQTTMDT
VHLLILAFLWLDSPENVDQALAQGHALNEKIALSHPLKPLPSEAKTQDIVTALDQLVQHF
GLGDYHQDLVKQVKAAFADPNQTLSAQLLPYIKDKSLAEFALNKALAYHDYDWTAHYALK
GYEEMELSTQMLLFDAIQKGIHFEILDEQDQFLKLWHQDHVEYVKNGNMTSKDNYVVPLA
MANKTVTKKILADAGFSVPSGDEFTSLEEGLAYYPLIKDKQIVVKPKSTNFGLGISIFQE
PASLDNYQKALEIAFAEDTSVLVEEFIPGTEYRFFILDGRCEAVLLRVAANVIGDGKHTI
RELVAQKNANPLRGRDHRSPLEIIELGDIEQLMLAQQGYTPDDILPEGKKVNLRRNSNIS
TGGDSIDVTETMDSSYQELAAAMATSMGAWACGVDLIIPDETQIATKENPHCTCIELNFN
PSMYMHTYCAEGPGQAITTKILDKLFPEIVAGQT
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atgacattaaaccaacttcttcaaaaactggaagctaccagccctattctccaagctaat
tttggaatcgagcgcgagagtctacgtgtcgataggcaaggacaactggtgcatacacct
cacccatcctgtctaggagctcgtagtttccacccctatattcagactgatttttgcgag
tttcagatggaactcatcacaccagttgccaaatctactactgaggctcgccgatttctg
ggagctattactgatgtagcaggccgctctattgctacagacgaggttctctggcctttg
tccatgccacctcgtctaaaggcagaggagattcaagttgctcaactggaaaatgacttc
gaacgccattatcgtaactatttggctgaaaaatacggaactaaactacaagctatctca
ggtatccactataatatggaactgggtaaagatttagttgaggccttgttccaagaaagt
gatcagaccgatatgattgccttcaaaaacgccctctatcttaagctggctcagaactac
ttgcgctaccgttgggtgattacctatctctttggggcctcacccatcgccgaacaaggt
ttctttgaccaggaagttccagaacctgtgcgttccttccgtaacagtgaccacggctat
gtcaataaggaagagattcaagtatcctttgtaagtctagaagattatgtctcagccatt
gaaacctatatcgaacaaggagatttgaatgcagagaaagaattttactcagctgttcgt
ttccgtggacaaaaggttaatcgttccttccttgacaaaggaatcacctacctagagttc
cgtaatttcgaccttaacccttttgagcgtatcggtattagtcagactactatggacact
gtgcacttactcattttagccttcctttggcttgatagccctgaaaatgtcgaccaagct
cttgcacaaggccacgcgttaaatgagaaaattgccctctctcatcctctaaaacctcta
ccttcggaggctaaaactcaggacattgtaactgccctagaccaactggtgcaacacttt
ggacttggtgactatcatcaagatctggttaaacaagttaaggcagcctttgcggatcca
aatcaaacgctctctgcccagctcttaccctatatcaaagacaaatctctagccgaattt
gctttaaacaaggctcttgcctatcatgattacgactggactgcccactatgctctcaag
ggctatgaagagatggaactctccacccagatgttgctctttgatgccatccaaaaggga
attcactttgaaatattggatgagcaagatcaattcctaaaactttggcaccaagaccat
gttgaatacgtcaaaaacggtaacatgacctcaaaagacaactacgtggttccccttgct
atggctaataagaccgtaaccaagaagattctagcagatgctggcttttcagttccttca
ggagacgaatttaccagtcttgaggaaggacttgcctactaccctcttatcaaggataag
caaattgttgtcaaacccaagtcaactaactttggtctgggaatttccattttccaagaa
cctgccagtcttgacaactatcaaaaagcccttgaaattgctttcgcagaagatacctct
gtccttgttgaagaatttattccaggaaccgaataccgtttcttcatcttggatgggcgt
tgtgaggctgtgcttctgcgtgtcgctgccaatgttattggtgatggcaaacacaccatt
cgtgaactagtcgctcagaaaaatgctaatccattgcgtggccgtgatcaccggtcacct
ctggaaatcattgagctaggagacatcgaacaactaatgttagctcaacagggttataca
cctgatgatattctcccagaaggaaaaaaggtcaatctgcgtcgtaattccaacatctct
acaggtggtgactctattgatgtcactgagaccatggattcctcttaccaagaattagcc
gcagccatggcaactagcatgggcgcctgggcttgcggggttgatctgataattccagat
gaaactcaaattgccaccaaggaaaatcctcattgcacctgcattgagctcaactttaac
ccttcgatgtatatgcacacctactgtgctgagggtcctggccaagctatcactactaaa
atcctagataaactttttccagaaatagtggctggtcaaacttaa
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