Streptomyces tuirus: GCM10017668_17350
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Entry
GCM10017668_17350 CDS
T07360
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stui
Streptomyces tuirus
Pathway
stui00300
Lysine biosynthesis
stui00550
Peptidoglycan biosynthesis
stui01100
Metabolic pathways
stui01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stui00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GCM10017668_17350 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GCM10017668_17350 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GCM10017668_17350 (murF)
Enzymes [BR:
stui01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GCM10017668_17350 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
BCL19892
UniProt:
A0A7G1NCJ3
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All DBs
Position
complement(1831859..1833265)
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AA seq
468 aa
AA seq
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MIALSLAEIAEVVGGQTHDIPDPSVQVTGPVVRDSREAGPGSLFVAFAGERVDGHDFAAA
VVEAGAVAVLGTRPVGVPAIVVDDVQTALGALARHVVARLGATLVALTGSAGKTSTKDLI
AQVLQRKAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGIGHISYLTELTPPKI
GLVLNVGSAHIGEFGGREQIAQAKGELVESLPEEGTAVLNADDPYVRAMASRTKAKVIFF
GESGEADVSAENVRLTDTGQPSFRLHTPSGASDVTMRLYGEHHVSNALAAAAVAHELGMS
ADEIAVALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMKAALRALAAMGKGRRTWA
VLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREAAWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRSELRPGDVVLVKASRSVGLESVAQALVESGAEGEVSAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcagaagtcgtcggcgggcagacgcacgacata
ccggatccgtccgtccaggtcaccggcccggtcgtccgggactcccgcgaggcggggccg
ggcagcctgttcgtcgctttcgccggggagcgcgtggacggccacgacttcgcggcggcg
gtcgtcgaggccggggcggtggccgtgctcggcacccgtccggtcggcgtgcccgccatc
gtcgtggacgacgtccagaccgccctcggcgccctcgcccggcacgtcgtggcccgcctc
ggcgccaccctcgtcgccctcaccggctcggcgggcaagaccagcaccaaggacctcatc
gcgcaggtgctccagcgcaaggcgccgacggtgttcacgcccggctccctcaacaacgag
atcgggctgccgctgaccgcgctcagcgcgaccgaggagaccaggttcctcgtcctggag
atgggcgcccgggggatcgggcacatcagctacctcacggaactgacccctccgaagatc
ggcctggtgctcaacgtcgggtccgcccacatcggcgagttcggcggccgtgagcagatc
gcccaggccaagggggaactcgtcgagtcccttcccgaggaggggacggccgtgctcaac
gcggacgacccctatgtccgggccatggcctcccgtacgaaggcgaaggtgatctttttc
ggtgagtccggcgaagcggacgtctctgccgagaacgtgcgactcacggacaccggacag
ccttcgttcaggcttcacacaccctccggtgcaagcgatgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttgggcatgtcc
gctgacgagatcgccgtggcgctctccgaggcgggctccctctcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaatcccgag
tccatgaaggccgcgctgcgcgcgctggcggccatgggcaagggacgtcgtacgtgggcg
gtgctcggcaagatggccgagctcggggacgaggctctcgccgagcacgacgcggtcgga
cggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcggcggcagggaagccgcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcggtcgacctgttgcgcagcgagttgcgcccgggggacgtcgtgctc
gtgaaggcgtcccgttcggtcggtctcgagagcgtggcgcaggcgctcgtcgagtccggt
gccgagggtgaggtttccgcccgatga
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