Streptomyces sp. VB1: OH133_10070
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Entry
OH133_10070 CDS
T11054
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
stvb Streptomyces sp. VB1
Pathway
stvb00470
D-Amino acid metabolism
stvb00550
Peptidoglycan biosynthesis
stvb01100
Metabolic pathways
stvb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stvb00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
OH133_10070
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
OH133_10070
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
OH133_10070
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
stvb01011
]
OH133_10070
Enzymes [BR:
stvb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
OH133_10070
Peptidoglycan biosynthesis and degradation proteins [BR:
stvb01011
]
Precursor biosynthesis
Amino acid ligase
OH133_10070
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
UZI28448
LinkDB
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Position
complement(2292646..2293821)
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AA seq
391 aa
AA seq
DB search
MSSENLPQSPERAESPVPQRRKPRVAVVFGGRSSEHGISVVTAGAVMKAIDRTKYDVLPI
GITTDGRWALTADEPERMAITDRKVPDVDRLTESAEGSVVLSVDPGSREVLYSEPGSVPK
ALGEVDVVFPVLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQDKEYMKRVFLSFGLP
VGPYEVVRPREWDNDPAAARERIVDFAGEHGWPLFVKPARGGSSMGITKVDSVEGLDEAI
EEARRHDPKFLVESLLRGREIECGVLEFEDGPRASVPAEIPPVTSHDFYDFEAKYIDSAA
GLVPAPLTEEQTAEVRRLAVAAFDAVSCEGLVRADFFLTEDGSFVINEINTLPGFTPISM
YPRMWQESGVSYPELVDRLIQAALSRSTGLR
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagaacctcccccagagccctgagcgcgccgagagccctgtgccgcagcgc
cgcaagccccgcgtggctgtcgtgttcggcggccgcagctccgaacacggcatctcggtc
gtcacggccggcgccgtcatgaaggccatcgaccggaccaagtacgacgtcctgccgatc
ggcatcacgacggacggccgctgggcgctcaccgccgacgagcccgaacgcatggccatc
accgaccgcaaggtccccgacgtggaccggctcaccgagtccgccgagggcagcgtcgtg
ctctccgtggaccccggcagccgtgaggtcctctacagcgaacccggctccgtgcccaag
gcgctgggcgaggtcgacgtcgtcttccccgtgctgcacggcccgtacggggaggacggg
accctccagggactcctcgaactctccggtgtgccctacgtcggcgcgggtgtcctcgcc
tccgccgtcggccaggacaaggagtacatgaagcgcgtcttcctctccttcgggctgccg
gtcggaccgtacgaggtcgtccgcccccgcgagtgggacaacgaccccgcggccgcccgc
gagcggatcgtggacttcgccggcgagcacggctggccgctgttcgtcaagcccgcccgc
ggcggctcctcgatgggcatcaccaaggtcgactccgtcgaaggactcgacgaggcgatc
gaggaggcccgccgccacgacccgaagttcctcgtcgagtcgctgctgcgcggccgcgag
atcgagtgcggggtgctggagttcgaggacggcccgcgcgccagcgtgcccgccgagatc
ccgccggtcacctcgcacgacttctacgacttcgaggccaagtacatcgactcggccgcc
gggctcgtgcccgcaccgctcaccgaggagcagaccgccgaggtgcggcgcctcgccgtc
gcggccttcgacgccgtctcctgcgagggcctggtgcgcgccgacttcttcctcaccgag
gacggctccttcgtcatcaacgagatcaacaccctgccgggcttcaccccgatctccatg
tacccgcgcatgtggcaggagagcggcgtcagctacccggagctggtcgaccggctgatc
caggccgcgttgagccgctccaccggactgcgctga
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