Streptomyces sp. VB1: OH133_10110
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Entry
OH133_10110 CDS
T11054
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
stvb Streptomyces sp. VB1
Pathway
stvb00290
Valine, leucine and isoleucine biosynthesis
stvb00660
C5-Branched dibasic acid metabolism
stvb01100
Metabolic pathways
stvb01110
Biosynthesis of secondary metabolites
stvb01210
2-Oxocarboxylic acid metabolism
stvb01230
Biosynthesis of amino acids
Module
stvb_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stvb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
OH133_10110 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OH133_10110 (leuC)
Enzymes [BR:
stvb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
OH133_10110 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
OH133_10110 (leuC)
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Ortholog
Paralog
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Motif
Pfam:
Aconitase
BON_like
DUF4946
Motif
Other DBs
NCBI-ProteinID:
UZI28455
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All DBs
Position
complement(2298527..2299954)
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AA seq
475 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKAGRPVRRLDLTIAT
EDHNTPTIDIDKPIADPVSRIQLETLRKNCADFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVEGELPDEVTA
KDLILAIIARIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDATTF
DYLEGRDHAPEGEDWDAAVAYWKTLRSDDDAVFDAEVVIDATELAPFVTWGTNPGQGAPL
SANVPDPASYEDASERFAAEKALEYMGLTAGQPLRDINVDTVFVGSCTNGRIEDLRNAAS
ILDGRKVARGVRMLVVPGSVRVALQAVSEGLDKVFTEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDARTPAGVR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccgacgcgcggagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacgggctgcgcaaggccggacgtccggtgcgacgcctcgacctgaccatcgccacc
gaggaccacaacaccccgaccatcgacatcgacaagccgatcgccgacccggtctcgcgc
atccagctggagaccctgcgcaagaactgcgcggacttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtggtgcacgtggtgggcccgcagctgggtctgacccagccc
ggcaccaccgtggtctgcggtgactcccacacctccacgcacggcgcgttcggcgcgctg
gcgttcggcatcggcaccagccaggtggagcacgtcctcgccacccagacgctgccgctg
gcccgcccgaagaccatggccatcaccgtcgagggcgaactgcccgacgaggtcaccgcg
aaggacctgatcctggcgatcatcgcccggatcggcaccggcggcggccagggctacatc
ctcgaataccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgccaccaccttc
gactacctcgagggccgcgaccacgcccccgagggcgaggactgggacgccgccgtcgcg
tactggaagaccctgcgctccgacgacgacgcggtgttcgacgccgaggtcgtcatcgac
gccaccgaactggccccgttcgtcacctggggcaccaaccccggccagggcgcgcccctg
tcggccaacgtccccgacccggcttcgtacgaggacgcctcggagcgcttcgccgccgaa
aaggccctggagtacatggggttgaccgccgggcagccgctgcgtgacatcaacgtcgac
accgtcttcgtgggttcgtgcaccaacggccgcatcgaggacctgcgcaacgcggcgtcg
atcctggacggccgcaaagtcgcgagaggggtacggatgctggtcgtgcccggctcggtc
cgggtcgcgctccaggccgtctccgagggcctggacaaggtgttcaccgaggccggcgcc
gaatggcggcacgcgggttgttcgatgtgcctcggcatgaaccccgaccagctggccccc
ggcgagcgctccgcctccacctcgaaccgcaacttcgagggccggcagggcaagggcggc
cgcacccacctggtctcgccccaggtcgccgccgccaccgcggtgctgggccatctggcc
tcgcccgccgacctgtccgacgcccgtacccccgccggagtccgatag
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