Streptomyces sp. VB1: OH133_19745
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Entry
OH133_19745 CDS
T11054
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
stvb Streptomyces sp. VB1
Pathway
stvb00280
Valine, leucine and isoleucine degradation
stvb00640
Propanoate metabolism
stvb00785
Lipoic acid metabolism
stvb01100
Metabolic pathways
stvb01110
Biosynthesis of secondary metabolites
stvb01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
stvb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
OH133_19745 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
OH133_19745 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OH133_19745 (pdhA)
Enzymes [BR:
stvb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
OH133_19745 (pdhA)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
HupE_UreJ
Motif
Other DBs
NCBI-ProteinID:
UZI30173
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Position
4348319..4349479
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AA seq
386 aa
AA seq
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MTVESTAAARKPRRASKRTSAAKKPQSAEPQLVQLLTPEGERVEHPDYSIDLSADELRGL
YRDMVLTRRFDAEATALQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGVAW
CRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHATGYAMGVAKDGADSAVIA
YFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTERQTRVPLYQRAQGYGFPG
VRVDGNDVLACLAVTRSALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRADEERAAWE
AKDPILRLRAYLEKDKLADEAFFTALDEESETLGKRVREAVRAMPDPDPMALFEHGYADG
NSLVDEERAQFAAYQASFADSAEEGK
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgccgcgcgtaaaccgcgacgcgccagtaagcggaccagc
gccgcgaagaagccgcagagtgccgagccccagctcgtacagctgctgacgcccgagggc
gagcgcgtcgagcacccggactacagcatcgacctgagcgccgacgagctgcgcggcctg
taccgggacatggtcctcacccgccgcttcgacgccgaggcgaccgccctccagcgccag
ggcgagctgggcctgtgggcctccctgctcggccaggaggccgcccagatcggcagcggc
cgggccctgcgcgacgacgactacgtcttcccgacctaccgggagcacggggtcgcctgg
tgtcgcggcgtcgacccgaccaacctcctcggcatgttccgcggggtgaaccacggcggc
tgggacccgaacagcaacaacttccacctgtacacgatcgtcatcggctcccagacgctg
cacgccaccgggtacgccatgggcgtcgccaaggacggcgcggactccgccgtgatcgcg
tacttcggtgacggggcctccagccagggcgacgtcgccgagtcgttcaccttctccgcg
gtctacaacgccccggtcgtcttcttctgccagaacaaccagtgggccatctccgagccc
accgagcgccagacccgcgtgccgctctaccagcgcgcccagggctacggcttccccggc
gtccgggtcgacggcaacgacgtcctcgcctgcctggccgtcacccgctccgcgctggag
cgcgcgcgccggggcgagggcccgaccctcgtcgaggcgttcacctaccgcatgggcgcc
cacaccacctccgacgacccgacgaagtaccgggccgacgaggaacgggccgcgtgggag
gccaaggacccgatcctgcggctgcgcgcgtacctggagaaggacaagctcgcggacgag
gccttcttcaccgcgctggacgaggagagcgagaccctcggcaagcgggtacgggaagcg
gtgcgtgcgatgcccgacccggacccgatggccctgttcgagcacggctacgccgacggc
aactccctcgtggacgaggagcgggcccagttcgccgcctaccaggcatcgttcgccgat
tccgccgaggagggcaagtag
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