Streptomyces sp. VB1: OH133_20250
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Entry
OH133_20250 CDS
T11054
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit PurL
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
stvb Streptomyces sp. VB1
Pathway
stvb00230
Purine metabolism
stvb01100
Metabolic pathways
stvb01110
Biosynthesis of secondary metabolites
Module
stvb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
stvb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
OH133_20250 (purL)
Enzymes [BR:
stvb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
OH133_20250 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
UZI30264
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Position
4471641..4473890
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AA seq
749 aa
AA seq
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MSLDTVKHAAGTPDAEQPWKELGLKEDEYARIREILGRRPTGAELAMYSVMWSEHCSYKS
SKVHLKQFGEKVPANDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYIEPYQGAATGI
GGIVRDILAMGARPIAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGEVVF
DACYQGNPLVNAGCIGVMRHEDIHLAQASGPGNKVILYGARTGGDGIGGVSVLASETFES
TGPAKRPAVQVGDPFQEKLLIECTLEIFKERLVAGIQDLGGAGLSCATSELASAGSGGMR
VELDTVPLRDSSLSPEEILMSESQERMCAIVEPQHVDRFLEICEKWDVIATVIGEVTEGS
QLEIFWHGEQIVDVPPRSVAHDGPVYHRPFARPSWQDALQADDAGKLARPANAAELREQV
LKLVASPNQASKAWITDQYDRFVQGNTVLAMPEDAGMVRIDAESNLGVAMATDGNGRYAK
LDPYTGAQLALAESYRNVAASGAKPLAISDCLNFGSPEDPDVMWQFAEATRGLADGCLEL
GTPVTGGNVSLYNQTGETAIHPTPVVAVLGVIDDVNRRTPIAFAEEGQLLYLLGDTTEEF
GGSAWSEVVHQHLGGLPPKVDLGREKLLAEILISASRDGMIDAAHDLSDGGLIQAVTESC
LRGGKGARLVVPDGLDAFTFLFSESAGRAVVAIPRSEELRFNDMCGARGLPVTRIGVVDG
EEIEIQGEFSIPLSELRTAHEATIPALLA
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgagcctggatacggtcaagcacgcggccgggaccccggacgccgaacagccctggaag
gagctcggcctcaaggaggacgagtacgcccggatccgcgagatcctgggccgccgtccc
accggcgccgagctcgccatgtactccgtgatgtggtcggagcactgctcgtacaagagc
agcaaggtccacctcaagcagttcggcgagaaggtccccgccaacgacgccatgctcgtc
ggcatcggcgagaacgccggcgtcgtggacgtcggccaggggtacgcggtcaccttcaag
gtcgagtcgcacaaccacccgtcgtacatcgagccctaccagggcgcggccaccggcatc
ggcggcatcgtccgcgacatcctcgccatgggcgcccgcccgatcgcggtcgtggacccg
ctgcgcttcggcgcggccgaccaccccgacaccaagcgcgtcctgccgggcgtcgtcgcg
ggcatcggcggctacggcaactgcctgggcctgcccaacatcggcggcgaggtcgtcttc
gacgcctgctaccagggcaacccgctggtcaacgccggctgcatcggcgtgatgaggcac
gaggacatccacctcgcgcaggcgtccggccccggcaacaaggtcatcctgtacggcgcc
cgcaccggcggcgacggcatcggcggcgtctccgtgctggcgagcgagaccttcgagtcc
accggccccgccaagcgccccgccgtccaggtcggcgacccgttccaggagaagctcctc
atcgagtgcaccctggagatcttcaaggagaggctcgtcgcgggcatccaggacctcggc
ggcgccgggctctcctgcgccaccagtgagctggcctccgccggttccggcggcatgcgc
gtcgagctggacaccgtgccgctgcgcgactcctccctctcgcccgaggaaatcctcatg
agcgagtcgcaggagcgcatgtgcgcgatcgtcgagccgcagcacgtggaccgcttcctg
gagatctgcgagaagtgggacgtcatcgccaccgtcatcggtgaggtgaccgagggctcc
cagctggagatcttctggcacggcgagcagatcgtggacgtgccgccgcgctcggtcgcc
cacgacggacccgtctaccaccgcccgttcgcccgcccgtcctggcaggacgcgctccag
gcggacgacgccggcaagctcgcccgcccggcgaacgcggccgagctgcgcgagcaggtc
ctgaagctggtcgcctccccgaaccaggcctccaaggcgtggatcaccgaccagtacgac
cgcttcgtgcagggcaacaccgtcctggcgatgcccgaggacgcgggcatggtccgcatc
gacgccgagtcgaacctgggcgtggccatggcgaccgacggcaacggccggtacgccaag
ctcgacccgtacaccggcgcgcagctcgcgctggcggagtcgtaccgcaacgtcgccgcc
tccggcgcgaagccgctggccatctcggactgcctgaacttcggctccccggaggacccg
gacgtcatgtggcagttcgccgaggccacccgcggtctcgcggacggctgcctggagctg
ggcaccccggtcaccggcggcaacgtctcgctgtacaaccagaccggtgagacggcgatc
cacccgacgccggtcgtggccgtgctcggcgtgatcgacgacgtcaaccggcgtacgccg
atcgccttcgcggaagagggccagctcctctacctgctgggcgacacgaccgaggagttc
ggcggctcggcctggtccgaggtcgtccaccagcacctgggcggcctgccgcccaaggtg
gacctcggccgcgagaagctgctcgccgagatcctcatctcggcctcccgcgacggcatg
atcgacgccgcgcacgacctgagcgacggcggcttgatccaggccgtcaccgagtcctgc
ctgcgcggcgggaagggcgcccggctggtcgtgccggacggcctggacgcgttcacgttc
ctcttctccgagtcggcgggacgcgcggtcgtcgcgatcccgcgcagcgaggagctccgc
ttcaacgacatgtgcggcgcgcgcggtctgcccgtcacccgcatcggtgtcgtggacggc
gaggagatcgagatccagggcgagttcagcatcccgctgagcgagctccgtacggcgcac
gaggcgacgatccccgcgctgctcgcctga
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