Streptococcus pyogenes MGAS1882 (serotype M59): MGAS1882_0044
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Entry
MGAS1882_0044 CDS
T02062
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase protein PurL
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
stx
Streptococcus pyogenes MGAS1882 (serotype M59)
Pathway
stx00230
Purine metabolism
stx01100
Metabolic pathways
stx01110
Biosynthesis of secondary metabolites
Module
stx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
stx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MGAS1882_0044 (purL)
Enzymes [BR:
stx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MGAS1882_0044 (purL)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
FGAR-AT_PurM_N-like
DJ-1_PfpI
GATase
Svf1_C
Motif
Other DBs
NCBI-ProteinID:
AFC67299
LinkDB
All DBs
Position
30814..34587
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AA seq
1257 aa
AA seq
DB search
MSSYFPVAPLSDLVSYMNKRIFVEKKADFGIKSASLVKELTHNLQLTSLKALRIVQVYDV
FNLAEDLLARAEKHIFSEQVTDCLLTETEITAELDKVAFFAIESLPGQFDQRAASSQEAL
LLFGSDSQVKVNTAQLYLVNKDITEAELEAVKNYLLNPVDSRFKDITLPLEEQAFSMSDK
TIPNLDFFENYQADDFTAYKAEQGLAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSD
HCRHTTFETELKNIDFSASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYER
ANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGA
IRDPLSGRSYVYQAMRISGAGDITTPIAEIRAGKLPQQVISKTAAHGYSSYGNQIGLATT
YVREYFHPGFVAKRMELGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSK
VQTVESVETAGAEVQKGNAIEERKIQRLFRDGNVTRLIKKSNDFGAGGVCVAIGELADGL
EIDLDKVPLKYQGLNGTEIAISESQERMSVVVRPNDVDAFIAACNKENIDAVVVATVTEK
PNLVMTWNGEIIVDLERRFLDTNGVRVVVDAKVVDKDLTVPEARTTSAETLEADTLKVLS
DLNHASQKGLQTIFDSSVGRSTVNHPIGGRYQITPTESSVQKLPVQHGVTTTASVMAQGY
NPYIAEWSPYHGAAYAVIEATARLVATGADWSRARFSYQEYFERMDKQAERFGQPVSALL
GSIEAQIQLGLPSIGGKDSMSGTFEDLTVPPTLVAFGVTTADSRKVLSPEFKAAGENIYY
IPGQAISEDIDFDLIKDNFSQFEAIQAQHKITAASAAKYGGVLESLALMTFGNRIGASVE
IAELDSSLTAQLGGFVFTSAEEIADAVKIGQTQADFTVTVNGNDLAGASLLAAFEGKLEE
VYPTEFEQTDVLEEVPAVVSDTVIKAKETIEKPVVYIPVFPGTNSEYDSAKAFEQVGASV
NLVPFVTLNEVAIAESVETMVANIAKANIIFFAGGFSAADEPDGSAKFIVNILLNEKVRA
AIDSFIEKGGLIIGICNGFQALVKSGLLPYGNFEEAGETSPTLFYNDANQHVAKMVETRI
ANTNSPWLAGVEVGDIHAIPVSHGEGKFVVSASEFAELRDNGQIWSQYVDFDGQPSMDSK
YNPNGSVNAIEGITSKNGQIIGKMGHSERWEDGLFQNIPGNKDQTLFASAVKYFTGK
NT seq
3774 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcctattttccagtcgctcccttgtcggacttggtatcttatatgaataaacgt
atttttgttgagaaaaaggctgactttggtattaaatcggctagccttgtgaaagagttg
acgcataatctacaactgacttctttgaaggctttgcgtattgtgcaggtctatgatgtc
ttcaatttggctgaggatttgctggcgcgtgctgagaagcatattttctctgagcaggtg
acagactgtcttttgacggaaactgaaatcactgcggagcttgataaggttgccttcttt
gccattgagtcgcttcctggtcaatttgaccaacgtgctgctagttcgcaagaagctttg
ctattatttggaagtgacagtcaggttaaggtcaatacagcccagctttacttggtcaat
aaggatattacagaagcagagcttgaagccgttaagaactatcttttgaaccctgttgat
tcgcgtttcaaggacattactttgccgcttgaagagcaggctttctctatgtctgataag
acgatccctaatcttgatttctttgaaaattatcaagctgacgattttacggcctataag
gcagagcagggcttggctatggaggtcgatgaccttctcttcatccaagattatttcaaa
tcaatcggacgtgtgccaactgagactgagttgaaagttttggatacttactggtcagac
cactgccgtcacacaacctttgaaactgaattgaagaacattgatttttcagcttctaaa
ttccaaaaacaattgcagacaacttatgacaaatatatcgccatgcgtgatgagcttggt
cgttctgaaaagccacaaacacttatggatatggcgactatttttggtcgttatgagcgt
gccaacggtcgtctggacgatatggaagtctcagatgaaatcaatgcctgctcagttgag
attgaagtagatgttgatggtgtgaaagagccttggctcctcatgtttaagaacgagact
cacaatcacccaacagaaattgagccatttggtggagcggcgacttgtatcggtggtgct
attcgtgacccattgtcagggcgttcatacgtttatcaggctatgcgtatttcaggcgca
ggcgatatcacgactccgattgcggaaatacgtgctggtaaattgccacaacaagttatt
tctaaaactgcggcgcacggctattcttcatatggtaaccaaattgggcttgcgacaact
tatgtgcgcgagtactttcaccctggcttcgtagccaaacgtatggagcttggagctgtg
gttggtgctgcacctaaggaaaatgtggttcgtgaaaaaccagaagcaggcgatgtggtc
atcttgctcggtggtaaaacaggtcgtgatggtgtcggtggtgcgacaggttcatctaag
gttcaaacggttgaatctgtggaaacagctggcgcagaggtacaaaaagggaatgccatt
gaagaacgtaagattcaacgtcttttccgtgatggcaatgtcactcgtcttattaagaaa
tcaaatgacttcggtgcaggtggtgtctgtgttgccatcggtgaattggctgacggtctt
gaaatcgatttggacaaggtgcctcttaaataccaaggtcttaatggtactgaaattgca
atctcagaatctcaagagcgtatgtcagtcgttgttcgtccaaatgatgtggatgccttc
atcgcagcctgcaacaaggaaaatatcgatgcagtcgttgttgcgaccgttactgaaaaa
ccaaatcttgtcatgacttggaatggcgaaatcatcgttgatttggaacgccgtttcctt
gataccaatggtgtccgtgtcgttgttgatgctaaagtcgttgacaaggacttgacagtt
ccagaagcacgcacaacatcagcagagacacttgaagcagatacgcttaaggtcttgtct
gacctcaaccacgctagtcaaaaaggtcttcaaactatctttgactcatctgttggtcgt
tcaaccgttaaccacccaatcggtggtcgttaccaaatcacaccgacagaaagttctgtt
caaaaattgccagttcaacatggtgtgacaacaactgcatctgttatggctcaaggttac
aatccttatattgcagagtggtcaccttatcacggtgctgcctatgctgtcattgaagcg
acagctcgcttggtagcaacgggtgctgactggtctcgtgcacgtttctcttaccaagag
tactttgagcgtatggataaacaggcagagcgttttggtcagccagtatcagctcttctt
ggttctattgaggctcagattcaacttggtttgccatcaatcggcggtaaggactctatg
tctggtactttcgaagacttgacagtaccaccaaccttggtagctttcggcgtgacaaca
gcggacagccgcaaggttctctctcccgagtttaaagcggctggcgaaaacatttactat
attccaggtcaagctatttcagaagatattgattttgaccttatcaaggataactttagc
cagtttgaagctattcaagctcaacataagattacagctgcctcagccgctaaatacggt
ggtgtcctagaaagtcttgctctcatgacttttggtaaccgtatcggtgcttctgttgaa
attgcagagcttgacagcagcttgacagctcaactcggaggttttgtctttacatcagct
gaggaaattgctgacgcggtgaaaatcggtcaaactcaggcagactttacagtcactgtc
aatggaaatgaccttgctggcgctagccttctagcagccttcgaaggcaaattggaagag
gtttacccaacagaatttgaacagacagatgttcttgaagaagttcctgctgtggtatca
gatactgttatcaaggctaaggaaacaattgaaaaaccagtggtttacattccagtcttc
cccggtaccaactcagaatacgattcagctaaggcctttgaacaggttggagctagtgtc
aacttggtaccatttgtaaccttgaatgaggttgctattgctgagtcagttgagactatg
gttgctaatattgctaaggcaaatatcatcttctttgctggaggtttctcagcagcagat
gaaccagatggctctgctaagtttatcgtcaatatcttgcttaacgagaaggtccgcgca
gctattgacagcttcatcgaaaaaggtggccttatcatcggtatctgtaatggtttccaa
gcccttgttaaatcaggtcttcttccatacggaaacttcgaggaagctggtgagacaagt
ccaactctcttctataacgatgctaatcagcatgttgccaagatggttgagactcgtatc
gcaaataccaactcaccttggttggcaggagttgaggtcggcgatattcatgccattcca
gtttcacatggtgaaggtaaatttgttgtcagcgcttctgaatttgcagagctaagagac
aatggtcaaatctggagccaatatgtggactttgacggacaaccatctatggattctaaa
tacaatccaaacggctctgtcaatgccatcgaagggattaccagcaagaatggtcaaatc
atcggtaagatgggacactcagaacgctgggaagacggactcttccaaaatatccctggt
aacaaagaccaaaccctctttgcaagtgctgtaaaatactttacagggaagtaa
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