KEGG   Streptococcus pyogenes Alab49 (serotype M53): SPYALAB49_000765
Entry
SPYALAB49_000765  CDS       T02019                                 
Symbol
rfbB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
stz  Streptococcus pyogenes Alab49 (serotype M53)
Pathway
stz00521  Streptomycin biosynthesis
stz00523  Polyketide sugar unit biosynthesis
stz00525  Acarbose and validamycin biosynthesis
stz00541  Biosynthesis of various nucleotide sugars
stz01100  Metabolic pathways
stz01110  Biosynthesis of secondary metabolites
stz01250  Biosynthesis of nucleotide sugars
Module
stz_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:stz00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    SPYALAB49_000765 (rfbB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    SPYALAB49_000765 (rfbB)
   01055 Biosynthesis of vancomycin group antibiotics
    SPYALAB49_000765 (rfbB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    SPYALAB49_000765 (rfbB)
   00525 Acarbose and validamycin biosynthesis
    SPYALAB49_000765 (rfbB)
Enzymes [BR:stz01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     SPYALAB49_000765 (rfbB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase NAD_binding_4 3Beta_HSD Polysacc_synt_2 RmlD_sub_bind NAD_binding_10 NmrA adh_short Sacchrp_dh_NADP KR
Other DBs
NCBI-ProteinID: AEQ24365
LinkDB
Position
737230..738270
AA seq 346 aa
MYKNIIVTGGAGFIGSNFVHYVYNNHPDVHVTVLDKLTYAGNRANIEAILGDRVELVVGD
IADAELVDKLAAKADAIVHYAAESHNDNSLEDPSPFIHTNFIGTYTLLEAARKYDIRFHH
VSTDEVYGDLPLREDLPGQGEGPGEKFTAETKYNPSSPYSSTKAASDLIVKAWVRSFGVK
ATISNCSNNYGPYQHIEKFIPRQITNILAGIKPKLYGEGKNVRDWIHTNDHSTGVWAILT
KGRIGETYLIGADGEKNNKEVLELILEKMGQPKDAYDHVTDRAGHDLRYAIDSTNLREEL
GWEPQFTNFSEGLEETIKWYTENETWWKAEKDAVEAKYAKTQEVIK
NT seq 1041 nt   +upstreamnt  +downstreamnt
atgtataaaaatattatcgtaactggtggagctggtttcatcggttctaactttgtacac
tatgtctacaataaccacccagatgttcatgtaactgtccttgataaattgacatatgca
ggtaaccgtgctaacattgaagctattcttggtgatcgtgttgagttagttgttggtgat
atcgctgacgctgaattggtagataaattggctgccaaagcggatgctattgttcactat
gcggctgagagccacaacgataactcattggaagatccaagtccatttatccatacaaac
tttatcggaacttacactttgcttgaagcagctcgtaaatacgatatccgtttccaccac
gtgtcaactgatgaagtttatggagatcttccacttcgtgaagaccttccaggacagggt
gaaggaccaggtgaaaaattcactgctgaaacaaaatacaatccatcatcaccttactca
tcaactaaggcagcttctgaccttatcgttaaggcatgggtacgttccttcggtgtgaaa
gcgaccatttcgaactgttcaaataactatggaccataccaacacatcgaaaaattcatt
ccacgtcaaattacaaatatcttggcaggaatcaaaccaaaactttatggtgaaggtaaa
aacgtccgtgactggattcatactaatgatcattctacaggagtatgggctattttgact
aagggtcgtatcggtgaaacataccttattggtgccgacggcgagaaaaacaacaaggaa
gttcttgaattgattcttgaaaaaatgggtcaaccaaaagacgcttatgatcacgtaact
gaccgtgctggtcacgatcttcgttacgctattgattctacaaacttgcgtgaagaactc
ggctgggaaccacaatttacaaacttttcagaaggtttggaagaaactattaagtggtat
acagaaaatgagacatggtggaaagcagaaaaagatgctgtagaagccaagtatgctaaa
actcaagaagtgattaaataa

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