Streptococcus pyogenes Alab49 (serotype M53): SPYALAB49_000882
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Entry
SPYALAB49_000882 CDS
T02019
Symbol
topA
Name
(GenBank) DNA topoisomerase I
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
stz
Streptococcus pyogenes Alab49 (serotype M53)
Brite
KEGG Orthology (KO) [BR:
stz00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
stz03032
]
SPYALAB49_000882 (topA)
03400 DNA repair and recombination proteins [BR:
stz03400
]
SPYALAB49_000882 (topA)
Enzymes [BR:
stz01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
SPYALAB49_000882 (topA)
DNA replication proteins [BR:
stz03032
]
Prokaryotic type
DNA Topoisomerases
SPYALAB49_000882 (topA)
DNA repair and recombination proteins [BR:
stz03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
SPYALAB49_000882 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_Top1
Toprim
C1_2
Toprim_4
DUF2996
HypA
Motif
Other DBs
NCBI-ProteinID:
AEQ24482
LinkDB
All DBs
Position
860992..863121
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AA seq
709 aa
AA seq
DB search
MGTKTTTKPKTGTKKSTTKKKSTAKKNLVIVESPAKAKTIEKYLGRSYKVVASVGHIRDL
KKSSMSIDFDNNYEPQYINIRGKGSLINSLKKEAKAAKKVYLASDPDREGEAISWHLSHI
LGLDPQDNNRVVFNEITKDAVKHAFVEPRQIDMDLVDSQQARRVLDRIVGYSISPILWKK
VKKGLSAGRVQSVALKLIIDRENDIKAFVPKEYWSIDGLFKKGTKKFQATFYGINGKKTK
LDNNNDVKEVLAKLTNEDFLVSKVDKKERRRNAPLPYTTSSLQQDAANKINFRTRKTMMV
AQQLYEGIHLGENGTQGLITYMRTDSTRISPVAQNDAAQFIINRFGANYSKHGNRVKNTS
GAQDAHEAIRPSSVNHTPDSIAKYLNKDQLKLYTLIWNRFVASQMTAAVFDTVKVNLEQN
GVLFVANGSQMKFDGYMAVYNDSDKNKMLPEMAEGETVKKISTSPEQHFTQPPARYSEAT
LIKTLEENGVGRPSTYAPTLEVIQRRYYVKLSAKRFEPTELGEIVNKLIVEFFPDIVDVA
FTAEMEGKLDQVEIGEEQWQHVIDQFYQPFVKELNKAESEIEKIQIKDEPAGFDCDVCGH
PMVIKLGRFGKFYACSNFPECRNTKAITKEIGVTCPVCHKGQVIERKTKKNRIFYGCDQY
PDCEFISWDLPIGRACPKSGDYLIEKKVRGGKQVMCSNETCDYKEEKIK
NT seq
2130 nt
NT seq
+upstream
nt +downstream
nt
ttgggaacaaaaactacaactaagccaaaaacgggtactaaaaagtccaccactaaaaag
aaatcaacagcgaaaaaaaatctcgttattgttgaatcacctgccaaagctaagactatt
gaaaaatatcttggacgcagttataaagttgttgcttcggtaggacatattcgtgactta
aaaaaatcgtctatgtctattgattttgataataattatgagccacaatacattaatatc
cgtggtaagggatcccttatcaattctttaaaaaaagaagccaaagctgctaaaaaagtt
tatttagctagtgacccggatcgtgagggagaggctatttcttggcatttgtcacatatc
ttaggacttgatcctcaagataataaccgagtggtttttaatgaaattacgaaagatgca
gttaaacatgcctttgtggagcctcgtcagattgatatggacttggtagattctcaacaa
gcacgtcgtgttttggaccgtattgtgggatattccatttcaccaattctttggaaaaag
gtcaaaaaaggactttcagcaggacgtgtccagtcggttgctttaaaactcatcattgac
cgtgaaaatgacatcaaagcatttgttccaaaggaatactggtctattgatggtcttttt
aaaaaaggaactaaaaagtttcaagcgactttttacggtattaatggcaaaaaaacaaag
cttgataataacaacgatgtcaaagaggtattagcaaagctaacaaatgaagattttctt
gtcagcaaggttgacaagaaagagcgacgtcgtaatgctcccttaccttacacaacatca
tctcttcaacaagatgctgctaataaaatcaatttcagaacgcgtaaaaccatgatggta
gcccaacaactgtatgaggggattcatttaggagaaaatggaactcaaggtttaattacc
tatatgcgtacggattctactcgtatcagtccagtagcacaaaacgatgctgctcaattt
attatcaatcgctttggagctaattattcaaaacatggtaatcgtgtcaaaaataccagt
ggtgcccaagatgctcacgaggcgattcgtccatctagtgttaatcatacgccagactct
attgccaaataccttaacaaggatcagttaaaactttatacgcttatttggaatcgtttt
gtggctagccaaatgacagcagctgtttttgataccgtaaaggtaaacttggagcaaaat
ggcgtgctttttgttgccaatggtagccaaatgaagtttgatggttacatggctgtttac
aatgattccgataaaaacaaaatgttacctgagatggcagaaggagaaacggttaaaaaa
atatcgacctctccagaacagcactttacgcagccaccagctcgttattctgaagcaact
ctgattaaaacgctagaagaaaatggtgttggacgtccatcaacttacgctccaacctta
gaagtcattcaacgcagatactatgttaaattgtctgctaagcgctttgagccaactgag
cttggggaaattgtcaacaagcttattgtcgaatttttcccagatattgttgatgttgct
tttactgccgagatggaaggtaagctagatcaagttgaaattggagaagaacaatggcaa
catgttatcgatcaattctatcaaccctttgtcaaagaattgaataaggctgagtctgaa
attgaaaagattcaaatcaaagatgaaccagctggcttcgactgtgatgtttgtggtcac
ccaatggtcattaagttaggacgttttgggaaattttacgcgtgtagcaacttcccagag
tgccgtaatacaaaagccatcactaaagaaattggtgttacttgtccggtttgtcataaa
ggacaagttatcgagcgtaaaaccaaaaaaaataggatattttatggttgtgatcagtat
ccagattgtgagtttatctcgtgggatttacctattggacgtgcttgccctaagtcaggt
gactatcttattgagaaaaaagttcgtggtggcaaacaagtaatgtgtagcaatgagacc
tgtgattacaaggaagaaaaaattaaatga
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