KEGG   Sceloporus undulatus (fence lizard): 121933158
Entry
121933158         CDS       T07740                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
sund  Sceloporus undulatus (fence lizard)
Pathway
sund00562  Inositol phosphate metabolism
sund01100  Metabolic pathways
sund04020  Calcium signaling pathway
sund04070  Phosphatidylinositol signaling system
sund04081  Hormone signaling
sund04082  Neuroactive ligand signaling
sund04261  Adrenergic signaling in cardiomyocytes
sund04270  Vascular smooth muscle contraction
sund04310  Wnt signaling pathway
sund04371  Apelin signaling pathway
sund04540  Gap junction
sund04621  NOD-like receptor signaling pathway
sund04912  GnRH signaling pathway
sund04916  Melanogenesis
Module
sund_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:sund00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    121933158 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    121933158 (PLCB2)
   04371 Apelin signaling pathway
    121933158 (PLCB2)
   04020 Calcium signaling pathway
    121933158 (PLCB2)
   04070 Phosphatidylinositol signaling system
    121933158 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    121933158 (PLCB2)
   04081 Hormone signaling
    121933158 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    121933158 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    121933158 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    121933158 (PLCB2)
   04916 Melanogenesis
    121933158 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    121933158 (PLCB2)
   04270 Vascular smooth muscle contraction
    121933158 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sund04131]
    121933158 (PLCB2)
Enzymes [BR:sund01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     121933158 (PLCB2)
Membrane trafficking [BR:sund04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    121933158 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    121933158 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 121933158
NCBI-ProteinID: XP_042328445
LinkDB
Position
1:322218749..322291188
AA seq 1210 aa
MSVLSPILTAPEMKEYMTKGERFIKWDDDSTNASPVILRVDPKGFYLYWTFQSKEIEFLD
ITSIRDTRVGKFAKIPKSQKLREVFNLDFPDNNFFLKTLTVVSGPDVVDLTFHNFVSYKE
NVGKDWADDIMAIVRNPFTYNASRYTFLEKILVKLKMQLNTEGKIPVRNIFQMFPADRKR
VEEALTACHLPKGKNDGINPEDFPEAVYKTFLMNLCPRPEINEIFTSHHSKAKPYMTKDH
LTQFINKKQRDSHLNDMLFPPAKPEQVQCLIEKYEPSGMNVQRGQLSPEGMVWFLCGPEN
SIVSQDKLLLYQDMNQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDC
WKGRPPEEEPIITHGFTMTTEILFKDAIEAIAESAFKTSPYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPQDLMGKILIKNKKNQFITGENQDTLKKGK
DPEYEVTDQTAPTESDSTASSGEVAEEIPEVEGDLENLDEEEIKKLQSDEGTAGLEVTAY
EEMSSLVNYIQPIKFDSFEVSSKKNQSYVVSSFTEMKAYELLSKFPIQFVDYNKRQMSRI
YPKGTRMDSSNYMPQMFWNVGCQMVALNFQTADVPMQQNMALFEFNGQSGYLLKHDFMRR
PDKQFDPFSVDRIDVVVASTLSITIISGQFLSERTVRSYVEVELFGLPGDPKRRYRTKLT
PNANSINPVWKEEAFVFEKILMPELASLRIVVLEEGGKFIGQRIIPVTAVRTGYHHVCLR
SESNMPLTMPSLLVYVNMKDYVPDSWADLTMALSNPIKFFNAHDKKSAKSQEKPDLQKSL
STTQLTTNELSNATGTYSIPPSNGPAGMFPTGKEEVLKEATKVTTEPQTASIEELQQIKA
FGKLLKKQEKELKELERKMIKRREELLQKYAVLFTELVAQPGKKKSPGTPKAPKKKSCRR
LPLDESRNAGEITENPDNRVLELKEKLEGELIQLGEEQYDCIRKKKEQHVTEQFAKIIEL
AREKQASELKELKESCESDTKEMKKKLEAKRLDKIQTMTKNTTDKGAQERLKKEINNAHI
QEVVQTVKQMNEKQTRYQQILETKQTACVEKIKEKENQLQQEAFAEYEGKVKSLNAEVQE
LVKNCVKVCFPLEADMTKEEALNAASEVNQESEEPLQGNNLTPETLKHEVQMAENAKEEE
ESTAVQESRL
NT seq 3633 nt   +upstreamnt  +downstreamnt
atgtcagtgctttcccctatcctgactgctccagaaatgaaggagtacatgactaagggt
gaacggttcatcaaatgggatgacgattccacaaatgcttcccctgtcattctacgggta
gatccaaagggattttatctatactggacctttcaaagtaaggaaatagaatttttggat
ataacaagcattcgagacactagagttgggaaatttgccaagattcctaagagccagaag
ctcagagaggttttcaacttggattttccagacaataactttttcctcaagacgttgaca
gtcgtttctggccctgatgtggtagaccttacatttcacaattttgtttcctataaagaa
aatgttggcaaggactgggctgatgatatcatggccattgttagaaacccgtttacatac
aatgcttcccgctatacgttcctggagaaaatactagtgaagctgaagatgcagctgaat
actgaggggaaaattcctgtcagaaatatttttcaaatgtttcctgcagaccgaaaaaga
gtagaggaagcattaactgcctgccatcttccaaaggggaagaatgatggcatcaatcca
gaagacttccctgaggcagtatacaaaacattcttgatgaatctgtgtcctcggccagaa
atcaatgagatatttacctcacaccattcaaaagccaaaccttacatgaccaaagatcat
ttgacacagtttatcaacaaaaagcagcgtgattcccacctcaatgacatgcttttcccc
cctgcaaagccagaacaagtgcaatgtctcattgagaaatatgagcccagtgggatgaat
gttcagagagggcaattatctccagagggaatggtttggtttctgtgtggtcctgaaaat
agcatagtatctcaggacaaactattgctgtaccaggatatgaatcaaccactctctcac
tacttcatcaactcatcccacaacacctatctaacagctggccagttttcaggaatttca
tctcctgaaatgtatcgccaaactctcttggctggttgccgctgtgtggaactggactgc
tggaagggtcgtcctccagaggaggagcccatcatcacccatggattcaccatgacaact
gaaatactcttcaaggatgcaattgaggctattgcagaaagtgctttcaaaacatctccc
tatccagtgatcctgtcctttgagaaccatgtggactcgcccaagcagcaggctaagatg
gctgaatactgcagaaccatatttggggacatgctactgacagaaccattagaaaaattt
ccactaaaaccaggagttcctctgccaagcccccaggatctcatggggaaaatcctgatt
aagaacaagaagaaccaatttataactggtgagaatcaggacactttgaagaaagggaag
gatccagagtatgaagtgacagaccagactgcaccaacagagagtgatagcacagccagt
tcaggtgaggtggcagaagagattcctgaagtggagggagacctggaaaacctggatgaa
gaagagattaaaaagctacagtctgatgagggtactgcaggtctggaagtgacagcttat
gaagaaatgtccagcttggttaattatatccagcccatcaagtttgactcttttgaagtc
tcttcaaagaagaaccaaagttatgtcgtttcctccttcactgagatgaaggcttatgaa
ctcttaagcaagttccccatccagtttgtggactataacaaaaggcagatgagtagaatt
tatcccaagggtacccggatggactcttctaactacatgcctcagatgttctggaatgtt
ggctgccaaatggtggccttgaacttccagacagcagatgtccccatgcagcagaacatg
gctctctttgaattcaatggacagagtggctatctccttaaacatgacttcatgcgtcgc
ccagataaacaatttgatcctttctcggtggatcgcattgatgtggtggtggcaagcact
ctctcgataacgatcatttctggccagtttctctcagaacgtactgtgaggtcatatgtg
gaagtggagttatttggactaccaggtgatcccaaacgaagatacaggaccaagctgacc
ccaaatgccaactcgatcaatcctgtatggaaggaggaggcttttgtatttgaaaagatt
ttgatgccggagttggcttctctcagaattgtggttttggaggaaggaggaaaattcatt
ggtcaacgcatcattcctgttactgctgtacgcactggctatcaccatgtttgccttcgt
agtgaaagcaacatgccacttacgatgccctctctccttgtctatgtgaacatgaaagac
tatgttcctgattcatgggcagacctcacgatggcactctccaacccaataaaatttttc
aatgcacatgacaaaaagtcagcaaagagccaagagaagccagatttgcaaaaaagcctt
tcaaccactcaactcactacaaatgaattatctaatgccacaggaacctatagtattcct
ccttcaaatggacctgcaggaatgtttcctacagggaaagaagaagtcttgaaagaagcc
acgaaagtaactacagagccacagacagcaagcattgaggagctacagcagatcaaggct
tttgggaaactactgaagaagcaagagaaggaactgaaagagctggagcggaagatgatc
aagcgcagagaagagctgttgcagaagtatgctgtccttttcacagagctggttgcccag
cctggcaaaaagaagagtccaggcactccaaaagcccccaaaaagaaaagttgcaggagg
ttacctttggatgagagcaggaatgctggggagataacagagaatcctgacaacagagtg
ttggagctgaaagagaagctggagggagaactaattcagctaggagaagagcaatatgat
tgcattcggaagaagaaagagcagcatgtcaccgagcaatttgctaaaataatagaactt
gcaagagaaaagcaagcatctgagctgaaggaactaaaagagtcctgtgaaagtgacact
aaggaaatgaagaagaaactagaggcaaagaggttggacaaaatccagaccatgactaag
aataccacagacaagggtgctcaggaaagactaaagaaagaaatcaataatgcccacatc
caggaagtagtacagacagtcaaacagatgaatgaaaagcagactaggtatcagcaaata
ttggaaacaaagcaaacagcctgtgtagaaaagatcaaggaaaaagaaaaccagctgcag
caggaggcctttgcagagtatgaaggaaaagtgaaatcgctcaatgcagaagttcaagaa
ttagtgaagaactgtgtgaaggtctgtttccctctggaagctgatatgacaaaggaagaa
gctctcaatgctgccagtgaggtaaaccaggagtcagaggagccacttcaaggaaacaat
ctgacacctgaaaccctaaagcatgaagtgcagatggctgagaatgctaaagaagaggag
gaatcaaccgctgttcaggaaagcagattgtga

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