Staphylococcus aureus subsp. aureus TCH60: HMPREF0772_11139
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Entry
HMPREF0772_11139 CDS
T01889
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
suq
Staphylococcus aureus subsp. aureus TCH60
Pathway
suq00290
Valine, leucine and isoleucine biosynthesis
suq00660
C5-Branched dibasic acid metabolism
suq01100
Metabolic pathways
suq01110
Biosynthesis of secondary metabolites
suq01210
2-Oxocarboxylic acid metabolism
suq01230
Biosynthesis of amino acids
Module
suq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
suq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
HMPREF0772_11139 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HMPREF0772_11139 (leuC)
Enzymes [BR:
suq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
HMPREF0772_11139 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
HMPREF0772_11139 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
ADQ76601
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Position
complement(1212286..1213656)
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AA seq
456 aa
AA seq
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MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFAT
LDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPG
KTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAK
DIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFE
YVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPF
PEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNI
TAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRN
FEGRQGKGARTHLVSPAMAAAAAIHGKFVDVRKVVV
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgggtcaaacattatttgacaaggtgtggaacagacatgtgttatacggaaaattaggc
gaaccgcaactattatacattgatttacaccttatacatgaagttacttctcctcaagca
tttgaaggacttaggcttcaaaacagaaaattaagacgcccagatttaacatttgcaaca
ctcgatcacaatgttcctactattgatattttcaatattaaagatgaaattgcaaacaaa
caaatcacaacattacaaaaaaacgccatagattttggggtgcatatttttgatatgggt
tctgatgaacaaggtattgttcacatggtgggacctgagacaggacttacacagcctggc
aaaacaatcgtttgtggtgactctcacacagcaacacatggagcatttggtgctattgca
tttggaattggaacaagtgaagttgaacatgttttcgcaactcaaacgctatggcaaaca
aaacccaaaaacttaaaaatcgatattaatggcaccttaccaacaggcgtctatgctaag
gacattattctgcatttaattaaaacgtatggtgttgattttggtacaggctatgctttg
gaatttactggtgaaacaattaaaaacctttcaatggacggtcgaatgactatttgtaac
atggctatcgaaggtggtgccaaatacggcataatccaacctgatgatataacatttgaa
tatgttaaaggtcgaccatttgccgataacttcgctaaatcagttgataagtggcgtgag
ctatattctgatgacgacgcgatatttgatcgtgtaattgaacttgatgtttcaacatta
gaaccacaagtgacatggggaactaatcctgaaatgggtgttaatttcagtgaaccattc
cctgaaatcaatgatatcaacgatcaacgtgcgtatgattatatggggttagagccagga
caaaaagctgaagatatcgacttagggtatgttttcctcggttcatgtacaaatgctaga
ctatcagatttgattgaagctagtcatattgttaaaggaaataaagttcacccaaatatt
acagctatcgtcgtaccaggttctcgtacagtaaaaaaagaagctgaaaaattaggtcta
gatactatctttaaaaatgcaggatttgaatggcgtgagccaggatgttcaatgtgttta
ggcatgaatcctgaccaagtacctgagggcgtacattgtgcatctacaagtaatcgaaac
tttgaaggacgacaaggcaaaggtgcaagaacacatttagtatcccctgctatggcagca
gcagcagctattcatggtaaatttgtggacgtaagaaaggtggttgtttaa
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