Staphylococcus aureus subsp. aureus TCH60: HMPREF0772_11487
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Entry
HMPREF0772_11487 CDS
T01889
Symbol
folC
Name
(GenBank) bifunctional protein FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
suq
Staphylococcus aureus subsp. aureus TCH60
Pathway
suq00790
Folate biosynthesis
suq01100
Metabolic pathways
suq01240
Biosynthesis of cofactors
Module
suq_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
suq00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HMPREF0772_11487 (folC)
Enzymes [BR:
suq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HMPREF0772_11487 (folC)
6.3.2.17 tetrahydrofolate synthase
HMPREF0772_11487 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ADQ76949
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Position
1587491..1588762
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AA seq
423 aa
AA seq
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MNYLESLYWIHERTKFGIKPGVKRMEWMLAQFNNPQNNIKGIHVGGTNGKGSTVAYLRTA
LVENGYEVGTFTSPFIETFNERISLNGVPISNDAIVELVSRIKPVSEMMERETDLGVATE
FEIITAMMFLYFGEIHPVDFVIVEAGLGIKNDSTNVFTPILSILTSIGLDHTDILGGTYL
DIARDKGAIIKPNVPVIYAVKNEDALKYVRERAIEQHAKPIELDREIVVVSQNDEFTYRY
KDYELETIILSMLGEHQKQNAALAITALIELNEQGLIELDFNKMIDGIESVRWTGRIEQV
HDKPLIILDGAHNSESIDALIDTIKQYHDKEKVDILFSAINGKPINEMVKHLSLIAHTFY
ATEFDFPKALRKEEIVGSIENDDIQLVDDYVEFIKNYQGDTLVITGSLYFISEVKSKLDF
EAL
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atgaattacctagagagcttgtattggatacacgaaagaactaaatttggcatcaaacca
ggtgttaaacgtatggaatggatgctagcacaatttaataatcctcaaaataacattaag
ggtattcatgtaggtggcacgaatggtaaaggctctacagttgcttaccttagaacagct
ttagttgaaaatggttatgaagtaggtacatttacgtctccgtttattgaaacatttaat
gaacgaattagtctaaatggtgtgccaatatcaaatgacgctattgtagaattagtatca
cgtattaaaccagttagtgaaatgatggaacgtgaaacagatttaggtgttgcaactgaa
ttcgaaataatcacagcgatgatgtttttatattttggtgaaatacatcctgttgatttt
gtcattgttgaggctggattgggtataaagaacgattcgacaaatgtctttacaccgatt
ttatcaatcttaactagtatcggtctagaccatacagatattttaggtggtacttatcta
gatattgctagggataaaggcgcgattataaagcctaacgttccagttatatatgctgtt
aaaaatgaagatgcattaaagtatgttcgtgaacgcgcaattgaacaacatgcaaagcca
attgaattagatagagaaattgttgttgtatcgcaaaatgatgaatttacttaccgttat
aaagattatgaattagaaacaatcattttaagtatgttaggtgaacatcagaaacaaaat
gctgcattagccataacagctcttattgaattaaatgaacaaggattaattgaattagat
ttcaataagatgatagacggtattgaatcagttcgttggactggacgtattgagcaggtg
catgacaaacctttaatcattttggatggcgcacataattcagagagtatagatgctcta
attgatacaattaaacagtaccatgataaagaaaaagtagatattttgttctcagcaata
aacggaaaaccgattaacgagatggtcaaacatttaagtttaattgcgcatacattttat
gcaactgaatttgattttccgaaagcgttacgcaaagaagaaattgtaggtagcattgaa
aatgacgatatacaattagtagatgactacgtagaatttataaaaaattatcaaggtgat
acattagtaattaccggtagtctgtacttcataagtgaagttaaatcaaaattagacttt
gaagcattataa
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