Sulfurifustis variabilis: SVA_0691
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Entry
SVA_0691 CDS
T05321
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sva
Sulfurifustis variabilis
Pathway
sva00300
Lysine biosynthesis
sva00550
Peptidoglycan biosynthesis
sva01100
Metabolic pathways
sva01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sva00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SVA_0691
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SVA_0691
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SVA_0691
Enzymes [BR:
sva01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SVA_0691
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxK
Motif
Other DBs
NCBI-ProteinID:
BAU47270
UniProt:
A0A1B4V1B2
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Position
682350..683720
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AA seq
456 aa
AA seq
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MMSLALLADVLKAPLTGADARFTGVSTDTRTIVAGDLFVALTGPRFDGHSFLPEAISRGA
SGAILSRRLETPLPYVHVADTRKALGDFASFWRRQFAIPVIAVTGSNGKTTVKEMIAAIL
AQRGPVLATRGNLNNDIGVPLTLLRLRAGDRHAVIEMGMNHAGEIDYLSRLALPSVAVIT
NAAEAHLAGLGSVEAIARAKGEIYAGLAADGVAIVNADDDFAGLWRDLARPRRVLSFGLD
HPADVTADYEPADTGIRLQLRTPDGEMAMRLPLLGKHNVMNALAAGAASLAAGAALADVK
SGLERLKAVSGRLELKEGISGARVIDDTYNANPGSLAAGLQVLKEARGERVLVLGDMAEL
GPSAADIHRRVGELAHSLGIQRLYAIGEFAALSARSFGPGGKHFTTPEALIEALIDCMHG
DMTLLVKGSRVMRMERVVAGIARRTQPATEAGHGVT
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgatgtcgctcgcactcctcgccgacgtgctcaaggcgccactgacgggcgcggacgcg
cgtttcacgggcgtgtcgaccgacacgcggacgatcgtcgccggcgaccttttcgtcgcg
ctcacgggaccccgcttcgacggtcacagcttccttcccgaagcgatctcccgcggcgcg
agcggcgcgatcctgtcgcgccggctggagacgccgctcccttacgtgcacgtggccgac
acgcgcaaggcgctcggcgacttcgccagcttctggcggcgccagttcgcgatcccggtg
atcgccgtgaccgggagcaacggcaagaccaccgtcaaggagatgatcgcggccatactc
gcgcagcggggaccggtcctcgcgacgcgcggcaatctgaacaacgacatcggcgttccg
ctgacgctgctccgcttgagggcaggcgatcgccatgccgtcatcgagatgggcatgaac
cacgccggcgaaatcgattatctctcgcgcctcgcgctgccgtcggtcgcggtgatcacc
aacgccgccgaagcgcatctggcgggcctcggaagcgtcgaggcgatcgcgcgcgccaag
ggcgagatctacgccggcctggccgccgacggcgtggcgatcgtgaacgccgacgacgac
ttcgccgggctgtggcgcgatctggccaggccgcgacgcgtcctcagcttcggtctcgac
caccccgccgacgtcacggcggattacgagccggccgacaccggcatccgactgcaacta
cgaacccccgatggagagatggcgatgcgcctccctttgcttggcaaacacaatgtgatg
aacgcgctggccgcgggtgccgcctcgctcgccgccggcgccgcgctcgccgacgtgaag
agcgggctcgagcggctgaaggccgtgtccggccggctcgagctcaaggaaggcatcagc
ggcgcccgcgtgatcgacgacacgtacaacgccaatcccggttcgcttgcggccggcctg
caggtgctgaaggaggcgcgcggggagcgcgtgctcgtgctcggcgacatggccgagctc
ggcccctcggcggcggacatccaccggcgcgtgggcgagctggcccacagcctcggcatt
cagcgcctctacgcgatcggtgaattcgccgccctctcggccaggagtttcgggcctggc
gggaagcacttcacgacgcccgaggcgctcatcgaggcgctgatcgactgcatgcacggc
gatatgacgctcctggtgaagggttcgcgggtgatgcggatggagcgcgtcgtcgcgggg
atcgcgcgccgcacgcagccggccacagaagccgggcacggggtgacttag
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