Streptomyces venezuelae: SVEN_1743
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Entry
SVEN_1743 CDS
T02274
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sve
Streptomyces venezuelae
Pathway
sve00300
Lysine biosynthesis
sve00550
Peptidoglycan biosynthesis
sve01100
Metabolic pathways
sve01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sve00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SVEN_1743
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SVEN_1743
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SVEN_1743
Enzymes [BR:
sve01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SVEN_1743
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
CCA55030
UniProt:
F2RI47
LinkDB
All DBs
Position
complement(1944351..1945775)
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AA seq
474 aa
AA seq
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MIALSLAEIAEIVGGQAHDIPDPAARITGPVVIDSREVRAGSLFAAFAGEHVDGHDYAER
AVAAGAVAVLAARPVGVPALVVDDVQTALGALARAVVERLGTDVVALTGSAGKTSTKDLI
AQVLDRHAPTVWTPGSLNNEIGLPLTALRASDETRHLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAEAKGELVEALPAAEDGGVAVLNADDPLVRAMASRTKARV
TLFGEADEAAVRAENVRLTENGQPSFRLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMPVEEIATALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGRAAQ
ARGARTWAVLGKMAELGDASLVEHDAVGRLAVRLNVSKLVAVGDREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEQVALALLDTEGEVTVR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgaaatcgtcggcgggcaggcgcacgacata
ccggatccggccgcccggatcaccggccccgtcgtcatcgactcccgcgaagtgcgggcc
ggcagcctcttcgcggccttcgccggtgagcacgtcgacggccacgactacgcggaacgc
gccgtcgccgccggtgcggtggccgtgctcgccgcccgcccggtcggcgtccccgcgctc
gtcgtcgacgacgtccagacggcgctcggggccctcgcccgagccgtcgtcgaacggctc
ggcaccgatgtcgtcgccctcaccggctcggccggtaagacctccaccaaggacctgatc
gcccaggtcctcgaccggcacgcgcccaccgtgtggacgcccggctcgctcaacaacgag
atcggcctgccgctcacggcgctccgcgcgagcgacgagacccggcacctggtcctggag
atgggcgcccgcggcatcgggcacatccgttacctcaccggcctcaccccgccccggatc
ggcctcgtcctgaacgtgggcaccgcccacatcggcgagttcggcggccgggagcagatc
gccgaggccaagggcgagctcgtcgaggcgctgccggcggccgaggacggcggcgtcgcc
gtcctcaacgccgacgacccgctcgtccgcgcgatggcgagccgcaccaaggcccgcgtg
accctcttcggcgaagcggacgaagcggccgtacgggccgagaacgtccgcctcacagag
aacggacagccttctttcaggcttcacacacccaccgggtgcagcgacgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgcagcggccgccgtcgcgcacgagctg
ggcatgcccgtcgaagagatcgccaccgcgctctccgaagcgggcaccctgtcgcgctgg
cgcatggaggtcaccgagcgtccggacggcgtgacgatcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgccctgcgcgcgctcgcggccatgggcagggccgcacag
gcccgaggggctcgtacgtgggcggtgctcggcaagatggccgagctcggtgacgcatcg
ctcgtcgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcggggacagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcaggcggctgtcgacctgttgcgcagtgag
ctgcgcccgggggacgtcgtccttgtgaaggcttccaggtcggtcggtctcgaacaggtc
gccctggccctcctcgacaccgagggcgaggtcaccgtccgatga
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