Streptococcus viridans: NCTC3166_00675
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Entry
NCTC3166_00675 CDS
T08046
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
svf
Streptococcus viridans
Pathway
svf00300
Lysine biosynthesis
svf00550
Peptidoglycan biosynthesis
svf01100
Metabolic pathways
svf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
svf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC3166_00675 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC3166_00675 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC3166_00675 (murF)
Enzymes [BR:
svf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC3166_00675 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Cellulase
Motif
Other DBs
NCBI-ProteinID:
VED66863
UniProt:
A0A3S4NCR0
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Position
1:606350..607720
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AA seq
456 aa
AA seq
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MNVTLHEVARVLAVRNDISQFEDFALQKPEFDSRLIGPGDLFVPLKGARDGHDFIETAFE
NGAVATLSEKEVEGHPYLLVDDVLGAFQKLAQYVLEKSQVDVLAVTGSNGKTTTKDMLAQ
LLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSEIAHPKAAI
VTLIGEAHLEFFKDRTEIAKGKLQIADGMPAGGLLLVPADPIVEDFLPNQQELVRFGEGA
DIRITKLDERKDSLTFEANFLSAAIDLPVTGKYNATNAMIAAYVALKEGVSEEAIRASFK
GLELTKNRTEWKKAGNGADILSDVYNANPTAMRLILETFSTIPANPNGRKLAVLADMKEL
GEQSIDLHNQMILSLSPDVLDTVIFYGQDIAGLAQLASQMFPLGHVYYFKKTAEEDQFED
MVKQVKESLKEQDQILIKGSNSMNLAKLVEELENGE
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaatgtaaccttgcacgaagtggctcgtgtcctggctgttcgcaatgatatcagtcaa
tttgaagattttgctttacagaagccagaatttgatagtcgtcttattggtccgggggat
ctctttgtccctctcaagggggcgcgtgatgggcatgattttattgaaaccgcctttgaa
aatggggctgtagcgaccttgtctgaaaaagaagtagaaggccacccgtatttgttggtg
gatgatgttctaggggcctttcaaaaattagcacaatatgttttggagaagagtcaagta
gatgtcttggcggtcaccggttcaaacggtaagacaacgaccaaagatatgttagctcag
ttattatctactacttataaaacctataaaacacaaggaaactacaataacgagattggc
cttccttatacggttctccatatgccagaaggaacagagaagcttgtccttgaaatggga
caggaccatctgggagatatccatctcctctcagaaattgcccatccaaaagcagcaatc
gtgaccctcattggggaagctcacctggagtttttcaaagatcgcacagaaatcgctaaa
gggaaattgcaaattgcggacgggatgccagctggtggcttgcttctagtaccggctgat
ccgattgtcgaggattttttacccaaccaacaagagcttgtgcgctttggtgaaggagca
gatatccgcattaccaaattggacgagcgcaaggacagcctgacttttgaagcgaatttc
ttgtcggctgccattgatcttccagtaacaggcaaatacaatgcgaccaatgccatgatt
gcggcctatgttgccctaaaagaaggggtgagcgaagaggctatccgtgcaagctttaaa
ggcctagagcttactaagaaccgcacagaatggaagaaggcaggtaatggagcggatatc
ttatccgacgtctacaatgccaacccaactgccatgcgcttaattttagaaaccttctcg
accattcctgccaatccaaatggccggaagttggcggttcttgcagatatgaaagaacta
ggggagcaatccattgatctgcacaaccaaatgattctcagtctttcacctgatgtcttg
gatacggttattttctatggtcaggacattgcgggcttggctcagttagcgagtcagatg
tttccactcggacatgtctactatttcaaaaagaccgctgaagaagaccagtttgaggac
atggtcaaacaagtcaaggaaagcttaaaagagcaggaccaaatcctcatcaagggaagc
aattctatgaatctagccaaattggtagaggagttggagaatggcgagtag
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