KEGG   Sturnus vulgaris (common starling): 106850308
Entry
106850308         CDS       T08833                                 
Symbol
PIK3CA
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
svg  Sturnus vulgaris (common starling)
Pathway
svg00562  Inositol phosphate metabolism
svg01100  Metabolic pathways
svg04012  ErbB signaling pathway
svg04068  FoxO signaling pathway
svg04070  Phosphatidylinositol signaling system
svg04081  Hormone signaling
svg04140  Autophagy - animal
svg04150  mTOR signaling pathway
svg04210  Apoptosis
svg04218  Cellular senescence
svg04370  VEGF signaling pathway
svg04510  Focal adhesion
svg04620  Toll-like receptor signaling pathway
svg04625  C-type lectin receptor signaling pathway
svg04810  Regulation of actin cytoskeleton
svg04910  Insulin signaling pathway
svg04914  Progesterone-mediated oocyte maturation
svg05100  Bacterial invasion of epithelial cells
svg05132  Salmonella infection
svg05164  Influenza A
svg05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:svg00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    106850308 (PIK3CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    106850308 (PIK3CA)
   04370 VEGF signaling pathway
    106850308 (PIK3CA)
   04068 FoxO signaling pathway
    106850308 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    106850308 (PIK3CA)
   04150 mTOR signaling pathway
    106850308 (PIK3CA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    106850308 (PIK3CA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    106850308 (PIK3CA)
  09143 Cell growth and death
   04210 Apoptosis
    106850308 (PIK3CA)
   04218 Cellular senescence
    106850308 (PIK3CA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106850308 (PIK3CA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106850308 (PIK3CA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    106850308 (PIK3CA)
   04625 C-type lectin receptor signaling pathway
    106850308 (PIK3CA)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106850308 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    106850308 (PIK3CA)
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    106850308 (PIK3CA)
   05168 Herpes simplex virus 1 infection
    106850308 (PIK3CA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106850308 (PIK3CA)
   05100 Bacterial invasion of epithelial cells
    106850308 (PIK3CA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:svg04131]
    106850308 (PIK3CA)
Enzymes [BR:svg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     106850308 (PIK3CA)
Membrane trafficking [BR:svg04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    106850308 (PIK3CA)
SSDB
Motif
Pfam: PI3Ka PI3_PI4_kinase PI3K_C2 PI3K_rbd PI3K_p85B DUF2321 ABC1 Ribosomal_S15
Other DBs
NCBI-GeneID: 106850308
NCBI-ProteinID: XP_014727012
LinkDB
Position
Unknown
AA seq 1068 aa
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDANAPHSRALYVYPPNVESSAELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKCPLSQYKYIRSCIMLGRMPNLMLMAKESLYTQLPLD
TFTMPSYSRRISTATPYMNGEATTKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSYAGQSNRIARDSELTESDKEQLRAICTRDPL
SEITEQEKDFLWRHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPSIKPEQAME
LLDCNYPDPMVRAFAVRCLEKSLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGDMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIA
YIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt   +upstreamnt  +downstreamnt
atgcctccacggccatcatctggtgaactatggggcatccatttgatgccccccaggatc
ctggtggagtgtctcctcccaaatggaatgatagtgactctagaatgcctccgtgaggcc
accttactgactattaaacatgaactctttaaagaagcaaggaagtaccctctctatcag
ctccttcaagatgagtcttcttacatttttgtaagtgttacacaagaagcagagagagaa
gagtttttcgatgaaacacggagactttgtgacctgcgactgtttcagcctttcctaaaa
gttattgaaccagtaggtaacagagaagaaaagattcttaatagagaaataggttttgct
attggcatgcctgtctgtgagtttgacatggtcaaggatccagaagtacaagacttcaga
agaaacattctcaatgtctgtaaagaagccgtggatctgcgagatgccaatgccccacac
agcagagcactgtatgtctatcctccaaatgtagagtcctcagctgagctccccaaacac
atctacaacaagctagacaaagggcaaattatagtggtgatttgggtaatagtctcacca
aacaatgataagcagaaatacaccctaaaaatcaatcatgactgtgtgcctgagcaagtt
attgctgaagcaattaggaagaaaactcgaagtatgttgctgtcatctgaacaactgaaa
ctttgtgtcttggagtaccagggcaaatatattttaaaagtctgtggctgtgatgaatac
ttgctagaaaaatgtccactgagccagtataagtacataaggagctgcatcatgcttggc
cgcatgcccaacctgatgctgatggccaaggagagcctgtacacgcagctgcccctggac
accttcaccatgccatcctactccaggcgcatctccacggccacgccctacatgaacgga
gaggccaccaccaaatccctctggactatcaacagtgctctcagaataaggatcctctgt
gcaacctatgtaaatgtgaacattagagacatagacaagatctatgttaggacaggtatt
taccatggaggggagcctttgtgtgacaatgtgaatactcagagggtaccttgttctaat
cccagatggaatgaatggctgttgtatgacatgtacattcctgatctcccacgtgctgct
cggctctgcctctccatctgctctgttaaaggccggaagggtgctaaggaggagcattgt
ccgttggcttggggaaatataaacatgttcgattacacagacactctggtatctgggaaa
atggctttgaatctttgggcagtacctcatgggctggaggatttgttgaatcctattggt
gttactggatcaaatccaaataaggaaactccatgcttagagctggaatttgattggttt
agcaaccctgtaaagtttccagatatgacagtgattgaagaacatgcaaattggacaatt
tcacgggaactgggattcaactacagctatgcagggcagagtaacagaatagctcgggat
agtgaattaacagagagtgacaaggagcaactgcgagccatttgtacccgagaccctttg
tctgaaatcactgagcaagagaaggacttcctctggagacacagacactattgcgtgaat
actccagaaattctacccaaattacttttgtctgtcaagtggaattctagagatgaggtg
gcccagatgtactgtttggtgaaggattggccctcaatcaaacctgagcaggccatggag
ctcctggactgcaattacccagacccaatggtgcgagcgtttgcagttcgctgtctggag
aagtccctgacagatgacaaactgtctcagtacctcatccagctggtacaggttctgaaa
tatgagcagtatttagataatcagcttgtgagatttttactcaagaaggcactgaccaat
caaaggataggacacttcttcttttggcatttaaagtctgaaatgcacaacaaaactgtc
agtcagaggtttggtttacttctggagtcctactgtcgagcatgtggaatgtacctgaag
cacctgagcaggcaggtggaggccatggagaagttgattaacctcacagatattctcaag
caggaaaaaaaggatgagactcagaaggtacagatgaagtttcttgttgaacaaatgaga
cggccagattttatggatgccttgcaaggttttatctctcctcttaatcctgcacatcaa
ctgggaaaccttcggcttgaggagtgcaggataatgtcatctgcaaaaaggccgctgtgg
ttgaactgggaaaacccagatattatgtctgaattattatttcagaacaatgagataata
tttaaaaatggagatgacttgcgtcaggacatgctgacacttcagataattcgaattatg
gaaaacatctggcaaaatcaaggtcttgatcttcggatgttgccttatggttgtttgtcg
attggtgactgtgtgggactcatcgaggtcgtgaggagctctcacaccatcatgcagatt
cagtgtaaaggaggcttaaaaggagcactgcagttcaacagccatacattgcaccagtgg
ctcaaggacaagaacaaaggagacatgtatgatgcagctattgacctgtttacacgttct
tgtgctggctactgtgttgccacctttatcctgggcattggtgaccgccacaacagcaac
atcatggtcaaagatgatggacaactgtttcacattgactttgggcacttcctcgatcac
aagaagaaaaaatttggttacaaaagagagcgtgtgccatttgtcttaacacaggacttc
ttaatagtgattagtaaaggagcccaagaatgtaccaaaacaagggagtttgaaaggttt
caggagatgtgttataaggcttacctggcaattcggcagcatgccaatctcttcatcaat
ctcttctccatgatgcttggctcaggaatgccagaactgcagtcctttgatgatattgca
tacattcgaaagacccttgcattggacaaaactgagcaggaggctcttgagtacttcatg
aagcaaatgaatgatgctcaccatggtggctggacaacaaaaatggactggatcttccac
acaataaagcaacacgctttgaactga

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