Sturnus vulgaris (common starling): 106860490 Help Entry 106860490         CDS       T08833                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism svg  Sturnus vulgaris (common starling) Pathway svg04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:svg00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     106860490 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:svg03036]     106860490 (SYNE1) Chromosome and associated proteins [BR:svg03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     106860490 (SYNE1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Motif Other DBs NCBI-GeneID:  106860490 NCBI-ProteinID:  XP_014743817 LinkDB All DBs Position Unknown AA seq 8802 aa AA seqDB search MASSRLVARSRDIANVMQRLQDEQESVQKRTFTKWINTHLAKRNPPMLVNDLFEDIKDGV MLIALLEVLSGQKLPCEQGRQLKRIHWVANIGTALKFLEGRRIKLVNINSTDIADGRPAI VLGLVWTIILYFQIEELTSNLPQLQPLSSSASSVESVVSSETASPPSKRKVVTKVQGSAR KALLKWLQYTAAKQVGIEIKDFGQSWRSGVAFHSVIHAIRPDLVDMEKVRGRSNRENLEE AFTIAEAELGIPRLLDPEDVDVEKPDEKSVMTYVAQFLKYYPDPHHTVTDVPENDKEDRL VLRDLKVWAEQFERDIARAQMAETSLQEKYQSFKHFRVQYEVKRKQFELATQSVRKDGKL SLDQAVVKQAWERVTSRMLDWHIHLDKSLPAPLGTIGAWLYRAEAALREEVTVQQAHEET ANTIHRKLEQHKDLLKNIDGHKKAFHEIHRTRSVNGVPVPHDQLEDMADRFNFVVSSSEL HLLKMEFLELKYRLLSLLVFAESKLKSWIIKYGRRESVELLLQNYISVIENSKFFEQYEV TYQILKRAAEMYAKANGSVEEVENVMKFMSDTTAQWRNLSVEVRSVRSMLEEVIANWDRY SSTVAGLQAWLEDAEKMLNQPEHSKKDFFRHLPHWIQQHTAMNDAGNFLIETCDETISRD LKQQLLLLNGRWRELFMQVKQYARADELDKIKKEYVDGVGHLTAFIDGSNKKFSTSVEVS FHDVKMFVQDLENIKQKLPAMEAQYKAVTRTVQLLTKEVSQEEANEMLGTLTRLKEQLGK VKEYSSALLYECQRLLSPLEELEKQITHFYESLEKVNEIISILDPEAQPTTVLKQKAQDL VAYQENCKKDVSLIERNSQSILQCMASTEVLQHFHQSTFQKKVTQVQLTFQNMVRKAGEW RKNIEANSRLMKKFEESRAELEKVIQIANCCLKEKGNPEELLRKHSEFFNQLDQRVLNAF LKACDELTDILPEQEQHSLQEAVRKLHRQWKDLQTEAPYHLIHLKIEVQKSKFLVTVEEC KAELARQNKVLSREGNERMIKEHMLFFGDKGSYHLCEKRLQRMEELCQKLPVSDPVRGTL ESSQRILKDLKSQIDSTYTKLTEHSDTWKGYKSRFSELANWISSTERELKKIKENVNDTA KYKQCKASVGEIRKHIQKHGENHSWLKSRLAVLTTLCPDLEAKATEDELCKLSSDFKRLL DLLAEIENTLGAVGDCVQYKEEVKSAIEELISNSKEVQAEAEKILDTESLLQAQQLLLHH QQRTRRLRAKRQDVQKQISQAKRLQIEGGLPSTVREDLQKLEGTLENMQQTMEKREEQLQ VTINKWEQFERDKETVVKYLNQASSVLERILNFSSLESLSSELDQTKELSKQTEAMAVQA ENLVKNSSEIQLGSKNKQSLQHQAKSIQEQVKKVEVTLEEDIKSMEMVKNKWNHFGNNFE ALSIWIAEQEKELETLETSSSPLDIQISQIKDINKEIDGKITGISNLEEEAKSFSQFVTS GECAHIKAKLTQVKRYWEELRDHAQRLEGIITGNASAQQKYEESLKQVQQSVSEFEAKLA EPLTSCSSAAATYAALQDCTDLCHAVEKLSSPLASLSAGVRKVTNKEKAAQEVTALQQKY EKVLESAKEKQSLLENLLAQWQKQEKELSAFLAWLEGCEATGRPSEQYVSADRIKLEGEL QALQELRADIESHTSVYESLLQLNESLFPTASKQCVKTIKEKFEELDERWKALPQIVDKR INFLQSLVAEHGQFDELLLRFSDWIKQFLAELQATSEINTADQQLAASHNKNHSMEVESR RQELQSLKEHVEKLGSFSSPEDQQTLQGKTEDCFQIFQEASQITSQRQNALDQLRVFLEL HSAASGVLHQLRQTVEKTGNMDKAKSELLEKELNGAIKDLNKLESDAVSLDGSLTKAQYH LKHSISGQRTSCRAMVDNLGVELEAVQNLLGTKQSEAEALGALQRSFMERKEQLLKSIED TEEKTDKEGLKETTLQALQQRLRIFNQLDEELNSHQHELQWLMDKAKQIAQKDITLAPET DKEINRLESLWKDTKKAIHEKKEQSCVLIDLMKEYQSLKSTVMKVIDSANSASVMKSIWK DHEDVRRTLSKHEVAKNDLSDKQKDLDTFTNKGKHLLAELKRVHNCDSTALKTDMNSTVD KWLDVSERIDDNIDRLSVSVSLWDDILKTGVELDGWCNKCISQLNEGINNFSNSQRMEIL LKDFQSEVKNKELKLEQLSSKISELKELTHSQEPPADLQFIESDVRQKLEHAKELSETAK EMLKDFSTQKMQLQKLIGQTTDWLTQVEETLLSCARNLDPEALNKLKETQKDLQLQQSSI DSTRETLNSLCRKYHSVELEALGGTVTLLIKKYEAVNLLCSRTQARMQESLEKHFLYSMQ EFQEWFSGVKAAVKESSDRSGDSKAIEAKLHDLQGVLDSISEGQKKLDAACKEGESLYGC LPKPVVSHIQEQIAKSNQNFQEFLSQCLNDKKALEACASHLGNFEDQYKKLALWMHDMEE RISTEALGENKQLVSEKKKEVQKVEKFLEELLNSRDSFDQLSQMAQTLNEEGHGAGREVR LASQHLTNYQNMVKSVKEKLRTCQLALQEHLTFEEALQSMWSWVKEVQDKLASSQSTLGS KATLEKRLTQIQEILLLKGDGEVKLNMAIGKGEQALKSSNEEGQKVIQTELQTLKDVWND IISTSVNWQSCLDSVISQWNDYLERKNQLEQWLENLDQKVEQPLEPQTGLKEKFAQLDHF QAIVSEIEDHSGDLQQLIEKAVELYEKTGDDSFGDAAQEELKTQFNDITTVAKEKMRKVE DIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDASGDTPTIQKKLAKLNELVESRQSGAGR LSRVEALAPAARRGTTAGGCQLLAAEMQALQADWRQWEESARRSQGGLRDLLSQMALSER EFAAQAGRLEEAVQRLGGQLAAWAQGLAPADSRSTDAEVVESWRKEKETLDALIKSEQMT DEIKTQLNDLCRFSRDLSTHSSKVSGLIKEYNSLCLQASKGCQSKEQILQQRFRTAFRDF QQWLVNARVTTAKCFDVPQNISEASASLQKIQEFLSESENGQQKLNLVASKGELLCSVLP KEKAKVIQDKSAAAKEDWKNFITTLHQKKSALENLKIQMKDFEATAEPLQEWLTTTEKIV QGSSSRLHDLPSKRREQQKLQSVLEEISCHEHQLNRLKEKAQQLWEEQAVSKSFMRRVSQ LSSQYLTLSNLTKEKVSRMDRIVAEHQQFSQSVKDLQDWIADAVHMLDSYCHPTADKSVL DSRMLKLEGLLAVKQEKEVQMKIVLTRGESVLQNTSLEGVPVIEGQLQNLKDSWASLLSA CIQCKSQLEGALSKWTSYQEDVNQFSRWMEKVEASMNASERQYAELREKTAALSKAKLLN EEVLSHNSLLETIEVKGKGMTEHYIAQLELQDLQERYKFLKERAKEAVTKTEGLLTLHQE YQRNLKAFEVWLEKEQEKLDCLSHVDGDAQEQEATLRDLQELQVHCAEGQALLNAAVHAR EEVIPWGIPQIEDRALESLRQDWQVYQHRLSEARSQLNATVSKLRLMEKKFQKVNDWLTN LEEKVAIRTGRRSGRATKEMQLQQMKKWHEDITIYKDDVEEVGVLAQQILEENLTASRMG NQATQLTSRYQTLLLHVLEQIKFLEEEIRCMEESELSFSAYTNWYGATNKNFKNVITKFD VVDKTIMEKKVQKLEVLLSDMDIGHSLLKSAREKGERAIKYMEENEVDQLRKEIGDHVEQ LEELASSIRKEHMTSEKCLQLVKEFSDKYKAQTQWVMEYQAILHAPVEPKSELYEKKAQL SKYKSIQQTVLSHEPSIKSVTEKGEALCDLVNDVTLKNNIQDLQSSYQELCTKTKAYVET LEVRVKEHEDYNSDLQEGEKWLLHMSSRLASPDLMESNNPEIITQQLANHKAIMEEITGF EDRLNNLKSKGDYLISQCSEHLQAKFKQNIQSHLQGTRDSYSAICSTAQRVYQTLEHELQ KHVNHQDTLQQCQTWLSTVQSELKPTTWTAFSLADAVKKVKHFRALQEQANTYLDLLCSM CDLSDATVKSTAADIQQTKQTIEQQIMHSQYLSQGWEEIKQLKAELWIYFQDADQQLQNL KRRRAELELNIAQNMVLQVKEFSQKLQSKQSALTSVTEKMNKLTQGQESPEHKEIGELSN QWLDLCLQAHNLLMQREEDLQRTKDYHDHMNVVEVFLEKLTKEWDNLARSDAESTNVHLE ALKKLAIVLQERRFALEDLKDQKQKIIEHLNLDDKELVKEQFSHFEQRWTQLEDLVKRKI QVSVSTLEELSLVHSRFQELMEWAEEQQPTVSEALKQSPPPDMAQSLLMDHLTICSELEA KQLVLKMLVKDADRVMTNLGLNERQELQKTVSDAQHHVACLSDLVGQRRKHLNKALSEKT QFLLAVFQATNQIHQHEKKVMFPEHICLLPEDVNKQIRTCKNTQANLKAYQNEVTALWAQ GRDLMKEATNQEKSEVLGKLQELQNVYDTVLQKCNQRLLELEKNIVSRKYFKEDLDKACH WLKQADIVTFPEVSVMNSDAELHSQLAKYQQILEQSPEYENLLLALQRDGQELLPSLNEV DHSYLDEKLNSLPQQFNIVTALAKEKLYKVQEAIYARKEYASLIELTNKALTELEDQFIN MDKAPAAVSAKEATSLQQTYRDLLDEAMSLAAAVEELNQKKEAFRSTGQPWQPDEMLKLA TLYHKLKRQIEQKINLLEDTIEACQEHEKMCMQFEAQLETVKKEQVKVNEETLPIEEKLK IYHSLVGSLQDSGSLLKRITEHLEALSPQVDSSAYETTNHQVQAWQEKLKSLHSAIVDTV MECENRLVQSIDFKTEICRSLDWLRWVKTELSGTLSLDLKLQNIQEEIRKVQIHQEEVQS SLRIMNALSNKEKESYMKAKELIPADLEHTLAELAELDGEVQEAIHLRQATLNKAYSLCQ RYYQVMQIANDWLEDAQEFLQLARNGLDVENSEENLRNHVEFFSTESQFNDNLKVLQGLV SEIEPFLQATASEQLVQNVAALEEKAKGTEQEAKTQQEQLQRCASEWQEYQTSRQKVIEM MNDAEKKLSEFSVAKAASSHEAEEKLLTHKTLVSIVNSFHEKITALEEKALQLEKISNDA SKASISRSMTTVWQRWTRLRNVAQEQEKILEDTVQEWKGFNDKIQKATISIDQLQGRLPE SSVEKASKTELLELLDYHGSFLLEVDHQLSSLGLLKQQAVSMLQDVEVKPPSQKELPVMQ EIKAMQDRCHNMQQKVKKGMKMVKQELKEREEVEAEINIVKSWIQETKEYLLSPDAEVDI QLQELQSLFGEVTTHRQAVEKLAEQQQNKYLGLYTILPSELSLHLAEVGLALVTVQEQIQ TKERETQQIKTLNQEFDQKIQGIANELNTILSKLKKKTNDIAQAKLEQKILGDELDSCNI KLLELDASVQDFAEQNVPLAKQLASRIGKLTALHQQTIRQAEYRAAKLSQAASHLEEYNE MLEFILKWIEKANILVHGSITWNSSSQLRDQFKAYQSILDESGEIHGDLEAMSERIDYLA SVYCTEGMSQQVLELGRRTEELQQVIKVQLPNLQDAAKDMKKFEIEVRALQAALEQAQAM LTSPELGHLSLKEQLSHRQHLLSEMESLKPKVQAVQDCQSALRIPEEVVTSLPMCHSALR LQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQDKPIATSNIQEL QVQISRNEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLSEGMEELDSD LLPAHPTHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQ DIAYYQALSAEQLQTEAAKIQSSTSATQEFYEPGLESSTSAKLDDLQRSWETLKNVISEK QRTLYEALERQQKYQDTLQSISTKMETTEIKLNESLEPAKSPESQMAEHQALMDEILMLQ EEISELQTSLAEELVSEPLDAEGADQMALQSTLTVLAERMATIRMKASGKRQLLEERLNE QLEEQRQEQALQRYRCEADELDHWLLSTRATLDTALLPAEEPMDMEAQLVDCQNMLVEIE QKVVALSELSVHNENLLMEGKAHTKDEAEQLAVKLRTLKGSLLELQRVLHDKQINIRQGS LQEKEETDLDFVSSQSPSVQEWLAQARTTRSQQQQNTLQQQKELEQELEEQKNLLRSVAC RGGEILTQQSSTEGLSISEKPDVLSEELVLEGEKPSSEEQMKRKWESLNQEFSTKQRLLQ KALEKEQLQLYSRPNRLIPGMPLYKEETQDEDKSLVSPVLVELNQAFEDVSSEAGRVEET LHLEQKLYDGVTATSVWLDGVEEQVFVATALLPEEETETYLCKQESLAKEIKDITEEVDK NKNLFAQVFPDSSDKRVIIEDTLDFLLRRLTLLESVVNQRCHQMKGRLQQIITFKNDLKL MFTSVADNKYLVLQKLAEAADRPETEQMQVILQAEEGLKELDAGINELKKRIDKLQIDQP SVQELSKIQDKYDELLMIIGSRRSDLNQNMALKRQYERALQDLADLVETGQEKMAGDQKM IVSSKEEVQSLLEKHKEYFQGLESHMILTETLFRKMSSLALLKETQSHAEIMTRASAILK LAHKRGVELEYILETWMHLDEDYQELTRQLESIEGNIPTVGLVEETEERLTDRITLFQHL RSNLTEYQPKLYQVLDDGKRLLFSVSCSELEGQLNQLGECWLSNTSKVNKELHRLETILK HWTRYQSESNELTQWLQSAKERLQFWSQQSLTVPQELETVRDHLNSFLEFSKEVDAKSSQ KSSVLSTGNQLLRLKKVDTAALRAGLSHIETQWTELLTQIPAVQEKLHQLQMDKIPSRHA ITEVMSWISLMENVIQQDEENIKNVVGQKAIQGYVQKYKGFKIDLNCKQLTVDFVNQSVL QISSQDVESKRSDKTDFAEQLGAMNRRWQILQGLITEKIQLLESLQESWTEYENNVQCLK TWFETQEKKLKQQQKIGDQASVQNALKDCQELEESIRAKEKEVENVEQSGLSLVQNKKEE VSSAVMNTLQEINHSWANLDHMVSQLKILLQSVLDQWSIYKVAYEELNNYLTEARYSLSR FYLLTGSLEAVKVQVDKLQSLQDELEKQENNLQKFGSVTNELLKECHPPVTETLTSTLKE VNMRWNNLLQEIAERLRASRALLQLWQRYRDCYQQCSSTLRQREDQTNELLKTATSKDIA DDEVTTWIRDCNDVLTDLKTAQESLVVLQELGEELKSQVEASAAAAIQSDHLSLNQNLST LEQALRKQQAALQAGVLDYQTFAKNLEVLETWITEAEETLKEQDPSHSSDVLAIQSRMEQ LKNQMLKFSSMTPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFL LQQQTFLEKCGTWMDLLVQTEQKLAVEVSGNYQRLLEQQREHELFQAEMFSRQQILHSII SDGQHLLEQGQVDDRDEFNLNLTLLSNQWQGVIRRAQQMRGIIDSRIHQWQRYREMAEKL RRWLLEMSCQPVTELGSAPIPLQQARVLLDEVQLKEKVLLRQQGSYILTVEAGKQLLLSA DSGAEAVLQAELTEIQERWKIVSTQLEQQKKQLTLLLKDWEKCEKGIGDSLEKLRSFKKK LSQPLPDHHDELHAEQIRCKELENAVEGWRDDLAHLSLLKETLSVYISADDISILSERIE LLHRQWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMI EKLKKDYQEEIAVAQKNKIQLQQMGERLAKASHESKASEIEYKLGKINDRWQHLLDLIAA RVKKLKETLVAVQQLDKNMNSLRSWLAHIESELSKPIVYETCDSEEIQRKLNEQQELQRD IEKHSTGVASVLNLCEVLLHDCDACATEAECDSIQQATRNLDRRWRNICAMSMERRLKIE ETWRLWQKFLDDYSRFEEWLKASERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQ LELINKQYRRLARENRTDSEGSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFET ARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNNNKIEQIIVQGEQLIE KSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLTDDEHDLSDREVDLDESADL SDIRWHDKSADSVLSPHPSSNLSLPLSQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDL DSVSRTLHSEEDGGQEKDFYLRGAAGIADVEIPETLEAYVTLTENALKNISGEPGALEAH IRQLDKALDTSRFQIQQTENIIRSKTPTGPELDSTYKGYMKLLGECSGSIDSVRRLGYKL KEEEEKFSGLINMNSTETQTAGVIERWELIQAQALSKELRMKQNLQQWQQFNSDLNSIWA WLGETEEELEKLHRLDLSTDIQTIELRIKKLKELQKAIDNRKAIILSINLCSSEFTQSDS EESKKLQERLSQMNVRWEHVCTMIEDWRSSLQDALIQCQDFHELSHGLLLWLENIDRRKN EIVPINPNLDSEILQEHHRLLMQIRRELLESQLKVASLQDMSCQLLVNAEGKDCLEAKEK VHVIGNRLKILLKEVTRHIKDLEKILDISSSQLELSSWSSDELDTSGSVSPVSGRSTPSR QRTPRGKCSLSQPGPSVSSPHSRSTRGGSGSSPSEAGPAWRCPSFFLRVLRAALPLQLLL LLLIGLACLVPMTEEDYSCAMANNFARSFHPMLKYMNGPPPL NT seq 26409 nt NT seq  +upstreamnt  +downstreamnt atggcttcatcccggctagtggcaagatctagagacattgccaatgtcatgcaacggctt caagatgagcaagagtcagtgcagaaacggactttcacaaaatggatcaatactcatctg gctaagcgcaatcctcccatgctggtgaatgacctgtttgaagatatcaaagatggggta atgctaattgcccttttggaggttctttcagggcagaagctgccttgtgagcagggacgt cagctgaagagaattcactgggttgccaacattggtacagctcttaagtttttagaaggt agacggattaagcttgtcaacataaactcaactgatattgctgatggtaggcctgctatt gtgcttggcttggtgtggaccataattttatattttcagattgaagagcttacaagcaac ctcccacagctgcagcccttgtctagcagtgcttcttctgtggaaagtgttgtcagttca gaaactgcaagtcccccaagcaaacggaaggtggtaaccaaggtccaaggaagtgccagg aaagctttgttaaaatggttacagtacacagcagcaaagcaagttggaattgaaatcaaa gattttggacaaagttggaggagtggtgttgcatttcattctgttattcatgctatccgc ccagatttagtggacatggagaaagtgaggggaaggtcaaatagagaaaacctggaagaa gccttcacaattgcagaagcagaactaggaatcccaaggctccttgacccagaagatgtg gatgttgaaaagccagatgaaaagtctgtcatgacctatgtagcccagtttttgaagtac tatcctgatcctcatcatacagtgactgatgtgccagagaatgataaagaagacagactg gtgctaagagacctaaaagtgtgggcagaacagtttgaaagagacatagcccgagcacag atggcagaaacaagcttacaagaaaaatatcagtcatttaagcatttcagagtacaatat gaggtaaaaaggaaacagtttgagctcgcaacccagtcagtaaggaaagatggtaaattg tcacttgatcaagctgtggtgaagcaagcatgggagagagttacttccaggatgcttgat tggcacatacaccttgataaatcccttcctgcacctttgggtaccataggtgcttggctc tacagggcagaggctgctctgagggaagaagtaactgttcagcaagctcatgaggaaaca gcaaacacaatacacaggaagctggaacagcataaggatctgctgaaaaacatagatggt cacaaaaaggcgttccatgagatccacaggaccaggtctgttaatggcgtgcctgttcca catgaccagttagaggatatggcagacaggtttaattttgttgtctcttcatctgagctc catctgttgaagatggagtttctggaactgaagtaccgtctactgtcactcttagtcttt gcagaatcaaagttaaaatcatggatcatcaaatatggaaggcgagaatccgtggaactg cttcttcaaaattatatttctgttattgaaaatagtaagttctttgagcagtatgaagtt acctaccagatcttaaaacgagcagctgaaatgtatgccaaagcaaatggctcagtggaa gaagttgagaatgtgatgaaattcatgagtgataccacagctcagtggaggaacctctca gtcgaggtcagaagcgtaagaagcatgctagaagaagtaattgccaattgggacagatac agcagcactgttgcaggtctacaagcttggcttgaagatgctgaaaagatgctgaatcag cctgaacattccaaaaaggacttcttccggcacttacctcattggatccaacagcacaca gctatgaatgatgctggtaattttctaattgaaacatgtgatgagaccatttccagagat cttaaacagcagcttctgttgctaaatggaagatggagagagctgtttatgcaagttaag cagtatgctcgagcagatgaactggacaaaattaagaaggagtatgtggatggtgtgggc catttgacagcttttattgacggaagcaataagaaattttcaacctctgtagaagtgtcc tttcatgatgtcaaaatgtttgtgcaagatttagaaaatattaagcagaaattgcctgca atggaagctcagtacaaagcagttacaagaacggtgcaacttcttacgaaagaagtttcc caagaggaagcgaatgaaatgctgggaactttgacacggctcaaagagcagctgggcaag gttaaggagtattccagtgccctgctgtatgaatgccagcgtctgctgtctccactggaa gaactggaaaaacaaatcacacatttttatgaatctcttgaaaaagtaaatgaaataatt tctatcttggatcctgaagcacaaccaacaactgttcttaaacaaaaagcccaagatttg gtagcttatcaagaaaactgcaagaaagatgtgtctctaattgagagaaatagtcagagt atccttcagtgtatggcttcgactgaagtgttacagcatttccatcagtcaacatttcag aagaaagttacacaagttcagcttacttttcagaatatggtcaggaaagctggtgagtgg agaaaaaacatagaagcaaatagccgtttgatgaagaaatttgaggagtctagagcagaa ctggagaaagtaatacagattgccaattgttgcttaaaagaaaaaggaaatcctgaagaa cttctcaggaaacatagcgaattttttaaccaattggatcagagagtcctaaatgccttt ctgaaagcgtgtgatgaacttactgatatcctcccagaacaagagcagcacagcctgcag gaagctgtgaggaaactccataggcagtggaaggatcttcaaacagaagccccatatcat ttgatccacttgaaaattgaagtacagaaaagcaagttcctggtgacagtggaggagtgc aaagctgaactagctcgacagaacaaggtgttatcaagagaaggcaatgaaagaatgatc aaggaacacatgttgttcttcggtgataagggatcttaccacctatgtgagaaaaggcta caacgaatggaagaactgtgccaaaagctcccagtttctgatccagtgaggggtactttg gaaagcagccagcgaatcctgaaggatctgaaatcccagatagacagcacatacacgaag ctaacagagcactcggacacctggaagggctataagagcagattttctgaattggcaaat tggatttcatcaacagaaagagagctaaagaagataaaggaaaatgttaacgatactgcc aaatacaagcagtgtaaagcatctgtgggggaaattaggaagcatattcagaagcatgga gaaaatcacagctggctgaaatctagacttgctgttttgaccactctgtgtcctgatttg gaggctaaagcgacagaggatgagctttgtaaactttccagtgacttcaagagacttcta gatttgctggctgagattgaaaataccttaggtgctgttggagactgtgtccagtacaaa gaagaagtcaaaagtgcaattgaagagttaatcagcaactctaaagaagtccaagcagag gctgaaaagatcttggatacagaaagtttattacaagctcagcagctactgcttcatcat cagcaaaggacaaggagactccgtgcaaaaagacaagatgtgcaaaagcagatttcccaa gccaagcggttgcagattgagggtggactgcccagcacagtacgagaggatttgcaaaaa ttagagggaacactggagaacatgcagcagactatggagaaacgggaagaacaactgcag gtcacaataaataaatgggaacagtttgaaagagacaaagaaacagtagtaaaatatctc aatcaagcaagctctgtacttgaacgtatcttaaattttagcagtttagagagcctctcc tcagaactggatcagacaaaggaactttctaaacaaactgaagcaatggcggtacaggct gagaatttggtgaagaattcctctgagatacagcttggttcaaagaataagcagtccctt cagcatcaggcaaaatcaatccaagaacaagtgaaaaaagtagaagttactcttgaagaa gatattaaaagcatggaaatggtgaaaaacaaatggaatcattttggcaataattttgaa gctctgtccatctggatagctgaacaagaaaaagaactggaaactttggaaacatcatca tctcctttggacatacagatcagccaaatcaaggatattaataaagagatagatggtaaa ataactggaatctctaatctagaagaggaagccaagtccttttcccagtttgttacctct ggagaatgtgcacatatcaaagccaaacttactcaggtcaaaaggtattgggaggaacta 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gccctgaggattcccgaggaggtggtcaccagcctgcccatgtgccacagtgccctgagg ctgcaggaggaggccagccgcctgcagcacacggccatccagcagtgcaacatcatgcag gaagcagtggttcagtatgagcaatatgagcaagaaatgaaacatttacagcagatgata gagagtgcccatcgtgagatccaagacaagccaatagcaaccagcaacatccaggagctc caggtccagatttcacgtaatgaggagctggctcagaagatcaaaggataccaggagcaa attgcttctttgaattccaagtgcaagatgctgacaatgaaagcaaaacatgccaccatg ctgctgacagtgacagaagtggaggggctgtccgagggaatggaggagctggattcagat ctgctcccagcacaccccactcatccctcggtggttatgatgactgctggtcgctgtcac acgctgctctcccctgtcactgaggagtctggggaggagggaaccaacagtgagatttct tctccacctgcctgtcgctctccctcacctgtggctaatacagatgcttctgttaaccag gacattgcttattaccaagccttatctgctgaacagttgcagacagaagctgctaaaatt caatccagcacctcagccacccaggagttttacgaaccaggcttagaatcatctactagt gccaaattggatgatttgcagcgttcttgggaaacactgaaaaatgtgatcagtgaaaag cagcgcacactctatgaagctcttgagcgtcaacagaagtatcaggacacactccagtct atatccacaaaaatggagaccactgaaatcaaactaaatgagagtttggaaccagccaaa agcccggagagccagatggctgaacatcaggctttgatggatgagattttaatgttgcaa gaagaaatcagtgagcttcagacatcattagccgaggagcttgtttcagaaccactggat gcagaaggtgctgatcaaatggcattgcagtccaccctcacagtcttggcagaacgaatg gccacaattcgaatgaaggcatcagggaaacgacagctattagaggaaagactgaatgag cagctcgaagaacagcggcaagagcaggctcttcagaggtaccgttgtgaagctgatgag ctggaccactggctcctcagtacccgagcaacgctggacaccgctctgcttcctgccgag gagcctatggatatggaagcgcagctggtagactgtcagaacatgctggttgaaatagaa cagaaggtggtagccttgtcagagttgtctgtgcacaacgagaacttgcttatggaagga aaggctcacaccaaggatgaggcagagcagctggctgtgaagctcaggacactgaagggc agccttctggagctgcagagagtgctccacgacaaacagatcaacattcggcagggatct ttacaagaaaaggaggagactgatctggacttcgtttcctcacaaagccccagtgttcaa gaatggctggcacaagcaaggactactcgctcacagcagcagcagaataccctgcaacaa cagaaagagctggaacaagagctagaagagcagaagaatctgcttcggtcagtagcatgc cgtggaggagagatcctgacacagcaaagctccactgaaggcctctctataagtgagaaa cctgatgtactctctgaggagttagtcttagaaggtgagaagccatcatctgaagaacag atgaagaggaaatgggaaagcctaaaccaggaattcagtaccaagcagaggcttctccag aaagctttggaaaaagaacagctgcagctttacagcagaccaaacagactaatacctgga atgcctttgtataaggaggagactcaggatgaagataaatccttagtgtcaccagtattg gtagaattgaatcaggcctttgaagatgtctcatctgaggctgggcgggtggaggagacc ctgcatcttgaacagaagctgtatgatggtgtcactgccacatcagtgtggctggatgga gtggaagagcaagtctttgttgctacagccctgttgccagaggaagaaacagaaacctac ctctgcaagcaagagtctcttgccaaagaaatcaaagacataacagaagaagtggataag aacaagaatttgtttgctcaggtatttcctgacagcagtgataagagggttattatagaa gacactttggattttctcctgagaagactgaccttactggagtcagtggtaaatcagaga tgccaccagatgaaaggacggctccagcaaatcatcacattcaagaatgatctgaagctc atgtttacatcggtggctgataacaaatacttagttctacagaaattagcagaggcagct gacagaccagaaacagaacaaatgcaggtcatactgcaggcagaagaaggtttaaaggaa ctagatgctggaatcaatgaattaaagaagcgtatagacaagctacaaattgaccaacct tctgtacaagagttgtctaagatccaggataagtatgatgagctgctgatgatcattgga tccaggcggagtgacctgaatcagaatatggctctgaagaggcagtatgaacgggctttg caggacctggctgacctggtagaaacaggccaagaaaaaatggctggtgaccagaaaatg attgtttcttccaaggaagaggttcaatcgctgcttgaaaaacataaggaatattttcaa gggttggagtctcacatgatcctgacagaaacactttttagaaagatgagtagccttgcc ctcttgaaggaaactcagtcacatgcagagataatgacacgagcttcagctatattaaag ctggctcataaacgaggtgtggaactggaatacattctagagacctggatgcacctggat gaagattaccaggaactcaccagacagctggagtctattgaaggaaacatccccactgtt ggtttggtagaagagacagaggagaggcttacagaccggattacactttttcagcatctg agatctaacctgactgaataccagcctaaattataccaagtgctagatgatgggaagagg ctccttttttctgttagctgctcagaacttgaaggtcaactgaaccaactaggagaatgt tggttaagtaacaccagcaaagtcaacaaggagcttcataggctggaaacaatactgaag cactggacaaggtatcagagtgaatcaaatgaattgacacagtggttgcaatctgcaaag gagcgacttcagttttggagccagcagtctttgactgttcctcaggaattagaaacagtc cgagaccacctgaactcctttttggagttttcaaaagaagtggatgctaaatcatcacag aaatcttctgtcctgagtactgggaaccaactcctcaggcttaagaaagtagatacagct gcattgcgtgcaggattgtcccatatcgaaacccagtggacagagcttctcacacaaatc ccagcagtacaagagaagttgcaccagctccagatggacaaaattccttctcgtcatgcc atcactgaagttatgagctggatttcgctgatggaaaatgtaattcagcaggatgaagaa aatataaaaaatgtagtaggacagaaagcaattcagggttacgtccagaagtacaagggt ttcaagatagatttaaattgcaaacagttgactgtagactttgtgaaccaatcagtgcta caaatcagcagccaggatgttgaaagtaaacgcagtgacaaaactgattttgcagaacag cttggagcaatgaacagacgttggcagatcctgcaaggcctgataacagaaaagatccag ctcttggaaagtttgcaggaatcttggacagaatatgaaaataatgtgcagtgcctaaaa acttggtttgaaacccaagagaagaagctgaaacagcaacagaaaattggagaccaggct tcagtacagaatgctttgaaagactgtcaggaattagaagaatcaataagagcaaaggaa aaagaagtagagaacgtggaacagagtggtctttctttggtacaaaacaagaaagaagaa gtctcttctgctgttatgaatactctgcaagaaattaaccattcctgggccaatttggat cacatggttagccagctgaagatattattgcaatccgttctggatcagtggagcatttac aaagtggcttatgaagaactgaacaattacctgacagaagccagatattctttgtcccgt ttttatcttcttactggttctctggaagctgtgaaagtccaagttgataaacttcagagc ctacaagatgaattggaaaaacaagagaataacttacagaaatttggttctgtgaccaat gagttgttgaaagaatgtcaccccccagtgactgaaacacttaccagcactttgaaagaa gtgaatatgaggtggaacaacctcctgcaggagatcgcggagcggctgcgtgccagcagg gccctgctccagctgtggcagaggtacagggactgctaccagcagtgctcttccacgctc cgacagcgagaagaccagaccaatgagctcctgaagactgcaaccagcaaagacatcgct gatgatgaagttactacttggattcgggactgcaatgatgtactcacagatttgaaaaca gcacaggagtctctggttgttcttcaagaactgggggaggagctaaaaagccaggtggag gcttcagcagcagcagccatacagtctgatcatctctctctgaaccagaatctgtcaacc ctagagcaggctctccgcaagcaacaggctgcactccaggctggagtcctggactatcaa acctttgctaagaacctggaagtccttgagacctggataacagaagcagaagaaacattg aaagaacaggatcccagtcactcatctgatgttttggcaatacagagtagaatggaacaa ctcaagaatcaaatgctgaagttcagcagcatgacccctgatttggaccgtcttaatgag ctgggttacaggcttcctctcaatgacaaggaaatcaaaaggatgcagaacctgaacaga cattggtctctgatctcatctcagactacagagagattcagtaaattgcagtctttcttg ctgcagcagcagacctttttggagaaatgtgggacttggatggatttattagttcagact gagcagaagttggcagtagaggtttcaggaaactaccaaaggcttttagagcaacagaga gaacacgagctattccaggcagagatgttcagccgccagcagattttgcattcaattatc tccgatgggcagcacctcctagaacaaggacaggtggatgacagggatgaatttaatctg aacctgactcttctgagtaaccagtggcaaggagtgattcgccgggcgcagcagatgcgg gggatcattgacagccgcattcaccagtggcagcgctacagggagatggcagagaagctg cgcaggtggctgctggagatgtcctgccagccagtaactgagctgggcagtgctcctatc ccattgcagcaagccagagtgctgctggatgaagtgcagcttaaagagaaagttctctta aggcagcaagggagttacatcctcactgtggaggctgggaagcagctgctgctctctgct gacagtggagcggaggcagtcctgcaggcagagcttactgaaatccaggagcgctggaag atagttagcactcagctggagcaacaaaagaaacagcttactttgctgctaaaagactgg gaaaaatgtgaaaagggcataggagactccctggagaagctaagatcattcaaaaaaaag ctttctcagccattgccagatcaccatgatgaattgcatgcagagcagatacgttgcaag gagttagagaatgctgttgaaggctggagagatgaccttgcacacctgtccctgctgaag gagaccctgtctgtatacatcagtgcagacgatatctccatcctgagtgagcgaatagag ctcctgcacaggcagtgggaggagctgtgccaccaggtctccttgcgtcgacaacaagtt agtgagagactgaatgagtgggctgtcttcagtgagaagaacaaggagctctgtgaatgg ctgacgcaaatggaaagtaaggtgtctcaaaatggtgacatcctcatagaagaaatgatt gaaaaacttaaaaaggattatcaagaggaaattgctgtagcccagaaaaacaaaatccag cttcagcaaatgggagagagacttgctaaagccagccatgagagtaaggcatcagagatt gagtacaaacttggcaagatcaatgacaggtggcagcatcttctagatcttattgcagcc agggtaaagaagttgaaggaaacccttgttgcagtgcagcagctggataaaaacatgaat agtctgagatcttggcttgcccacattgagtcagagctgtccaaacctatcgtctatgaa acttgtgactctgaggagatacaaaggaagctaaatgaacagcaggaactccagagggac atagagaaacacagcactggcgtggcatctgttctcaatctgtgtgaagtacttcttcat gactgtgatgcttgtgccacagaagcagagtgtgactctatccagcaggctacacgcaat ctggacagaaggtggagaaatatttgtgcaatgtcaatggaaaggcgacttaaaattgaa gagacctggcggctatggcaaaaatttttggatgactactctagatttgaagagtggcta aaagcctctgagaggacagctgctttcccaagctcctctggtgtgctttacactgttgct aaggaagaactgaagaaatttgaggctttccagagacaagtgcatgaaagcctgactcag ctggagctgatcaataagcaatatcggcgcctggcacgggagaaccgcactgactccgag ggcagcctcaagcagatggttcacgaggggaaccagagatgggacaacttacaaaagcga gttacctccatcctgcgcaggctaaaacattttattggccagcgtgaggagtttgaaaca gcacgtgacagcatcctggtatggctaacagagatggatctgcagctgaccaacatcgag catttctctgagtgtgatgtccaagcaaagataaagcaacttaaggctttccagcaagaa atttccctgaacaacaacaaaattgagcagataattgttcaaggtgagcaactcattgaa aaaagtgagcccctggatgcagctgtaattgaagaagaactcgatgagctgcgtcgttac tgccaagaggtctttgggcgtgtggagcgctaccacaagaaacttattcgccttcctcta acagatgacgagcacgacctctctgacagagaggtggatctggatgaatcagcagatctc tctgacatacgctggcatgacaaatctgcggacagcgttctctccccgcacccctcttcc aacctttcgctgcctctttcccagccgctgaggagcgagcgatcggggcgggatacccct gccagcgtggactccatccccctggagtgggatcatgactacgaccttagcagggacctg gactctgtctcacggactctgcactctgaagaagatggaggacaagaaaaagacttctac ctgagaggagcagccggcatagcagatgtagagatccctgaaactcttgaggcctatgta acactcacagaaaacgccctcaaaaatatatctggtgaaccgggtgccctggaagcacat atccggcagctggacaaggccttggacaccagccgcttccagatacagcaaacagaaaac atcatccgcagcaagacacctacaggacccgagctggattccacttacaaaggatatatg aaactgctaggtgaatgcagtggaagcatagactcagtaagaagacttgggtataaactg aaggaggaagaagaaaaattttcaggactcattaacatgaacagtactgaaacacaaaca gctggtgtaattgaaagatgggaattaatccaggctcaagctctaagcaaggagctgagg atgaagcagaaccttcagcaatggcagcagttcaactccgaccttaatagcatctgggct tggttgggagaaactgaagaggaactggagaagctgcaccgccttgatctcagcactgac atacaaactattgagctcagaattaaaaaactgaaagagctgcagaaagcaattgataac cgcaaagcaatcatcttgtccatcaatctgtgcagctcagagttcactcagtctgacagt gaggagagcaagaagcttcaggagcgcctgtctcagatgaacgtgcgctgggagcacgtg tgcaccatgatcgaagactggcgcagctccttgcaggatgcattgatacagtgccaggat ttccatgaactgagccatggtttgctgctttggttggagaatattgacagaagaaaaaat gagattgtgcccatcaatccaaacctggactcagaaatactgcaggaacatcacagactt ctgatgcaaatcagacgtgaactgctggagtctcagttgaaggtggcgtcactgcaagat atgtcttgccaattgctagtcaatgctgaaggcaaggactgtcttgaagccaaagaaaag gtacatgtcattggaaatagactgaagatcctcttgaaagaggttacacgtcatattaaa gacctagagaaaattttagacatttcaagtagtcaactggaattgtcctcatggtcttct gatgaattagacacatcaggctcagtgagtcctgtatctggaagaagcactccaagcaga cagagaacgccacggggcaaatgtagtctctcacagcctggaccctctgtcagcagtcca catagcaggtccacaagaggtggctcaggttcctccccttctgaggctgggccagcctgg cggtgcccttccttcttcctcagagtcctcagagctgctctgccacttcagctcctcctg ctgctcctgatcgggctggcgtgcctggtgccaatgaccgaggaggattacagctgtgct atggcaaacaactttgcccgctccttccaccccatgctgaaatacatgaatggtcctcct ccattgtga

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