Streptomyces violascens: HWN34_00900
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Entry
HWN34_00900 CDS
T08842
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
svio
Streptomyces violascens
Pathway
svio00300
Lysine biosynthesis
svio00550
Peptidoglycan biosynthesis
svio01100
Metabolic pathways
svio01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
svio00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HWN34_00900
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HWN34_00900
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HWN34_00900
Enzymes [BR:
svio01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HWN34_00900
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QLA55224
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Position
202493..203872
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AA seq
459 aa
AA seq
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MSLTAVAEAVGGRLADVLDPAVQVTEPAVFDSREAGPGSLFVALAGEHADGHAFAESAHN
KGAVVALVNRPVGVPAIVVDDVLRAFGRLAHTLLTGPLAATRVVAITGSAGKTSTKDFVS
QVLPGSVVATPQSFNNEIGLPLTVTMADTTTDHLVLEMGARHIGDIRDLTLVAPPDISIV
TNVGTAHIGEFGGRDNIAEAKGEIVEALAPGGLAVLNADDDYAQPMRERAGGSVVTFGLG
EDADIRATDLSTDAHGRASFTLVTPEGSAPVRLQFVGGVQVHNSLAAAAVGRGAGLAPEE
IAARLSQALPRSRWRMETVTRADGVTVVNDAYNANPTSMRHALEALASMAGGVEQRSVAV
LGRMNELGDDARAAHEEVGRYAAAQGLDTIILVGGDEAAWMRDGVREAGGRATWVPDQEA
ALGLLHSTLRPGDVVLVKASRGVQLQRLAEELLNPAAPA
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgtctttgaccgccgtcgccgaagccgtcggtggccgtctcgcagatgtcctcgacccc
gccgtccaggtcaccgaacccgccgtcttcgactcacgcgaggccgggcccggctccctc
ttcgtcgcactggcgggcgagcacgcggacggtcacgccttcgcggagtccgcccacaac
aagggtgccgtcgtcgcgctggtcaaccgcccggtcggcgtaccggcgatcgtcgtggac
gacgtactccgggcgttcggcaggctggcgcacaccctgctgaccgggccgctggccgcc
acccgcgtcgtcgccatcaccggctcggcgggcaagaccagcaccaaggacttcgtctcg
caggtgctgcccgggtccgtggtcgccaccccgcagtccttcaacaacgagatcggcctg
cccctgaccgtcaccatggccgacacgaccaccgaccacctcgtcctggagatgggcgcc
cgccacatcggggacatccgcgacctcaccctcgtcgccccgcccgacatcagcatcgtc
accaacgtcggcacggcgcacatcggcgagttcggcggccgggacaacatcgccgaggcc
aagggcgagatcgtcgaagccctcgcgccgggcggcctggccgtgctgaacgccgacgac
gactacgcgcagccgatgcgtgagcgcgccggaggctccgtggtgaccttcgggctgggc
gaggacgccgacatccgcgccacggacctcagcacggacgcgcacggccgcgcctccttc
accctcgtcacgccggagggcagcgccccggtccggctccagttcgtcggcggcgtccag
gtgcacaacagcctggccgcggccgccgtcggccgcggagccggcctcgcccccgaggag
atcgccgcccgcctctcccaggcactgccgcgctcgcgctggcggatggagaccgtgacc
cgcgccgacggcgtcaccgtcgtcaacgacgcctacaacgccaatcccacctcgatgcgg
cacgccttggaggcgttggcctcgatggcaggcggggtggagcagcggtcagtggcggtg
ctcgggcggatgaacgagctgggggacgacgcccgcgccgcgcacgaggaggtcgggcgg
tacgccgccgcacaggggctcgacacgatcatcctggtgggcggcgacgaggccgcctgg
atgcgcgacggcgttcgggaggcgggcggccgggccacgtgggtaccggaccaggaagcc
gctctcggcctgctccactcgacgctccggcccggtgacgtggtcctggtgaaggcgagc
cgcggggtccagcttcagcggctcgcggaggagctgctgaacccggcggcgccggcctag
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