Streptomyces violaceusniger: Strvi_1887
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Entry
Strvi_1887 CDS
T01602
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
svl
Streptomyces violaceusniger
Pathway
svl00290
Valine, leucine and isoleucine biosynthesis
svl00620
Pyruvate metabolism
svl01100
Metabolic pathways
svl01110
Biosynthesis of secondary metabolites
svl01210
2-Oxocarboxylic acid metabolism
svl01230
Biosynthesis of amino acids
Module
svl_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
svl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Strvi_1887
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Strvi_1887
Enzymes [BR:
svl01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Strvi_1887
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
AEM81622
UniProt:
G2P280
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All DBs
Position
1797472..1799070
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AA seq
532 aa
AA seq
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MKDLPDDGFHVFDTTLRDGAQREGINLTVADKLTIARHLDDFGVGFIEGGWPGANPRDTE
FFARARAEIDFRHAQLVAFGATRKAGARAEDDRQVKALLDSGAPVITLVAKSHDRHVELA
LRTTLEENLAMVRETVAYLRSQGRRVFLDCEHFFDGYRANADYAKQVVSAAHEAGAEVVI
LCDTNGGMLPGQIDAVVRTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTANG
YGERVGNANLFPVVAALELKYGRRVLPEGALEEMTRISHAIAEVVNLTPSTHQPYVGVSA
FAHKAGLHASAIKVDPDLYQHIDPERVGNTMRMLVSDMAGRASIELKGKELGIDLGDDRA
LVGRIVERVKERELAGYTYEAADASFELLLRQEVDGRPRRYFRVESWRAIVEDRPDGTHA
NEATVKLWAKGERIVATAEGNGPVNALDRALRVGLERIYPQLATMELVDYKVRILEGKHG
TESTTRVLVSTADGQGEWSTVGVGENVIAASWQALDDAYAYGLLRAGVDPQE
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgaaggatctgcccgacgacggcttccatgtcttcgacaccaccctgcgcgacggagcg
cagcgcgagggcatcaacctgacggtcgcggacaagctgaccatcgcccgtcacctggac
gacttcggcgtgggcttcatcgagggcggctggcccggcgccaacccgcgcgacacggag
ttcttcgcccgggcccgcgccgagatcgacttccggcacgcccagctcgtggcgttcggc
gccacccgcaaggcgggggcacgcgccgaggacgatcgccaggtcaaggcgctgctggac
tccggggcgccggtgatcaccctggtggcgaagtcccacgaccgccatgtggagctggcc
ctgcgcaccacgctcgaggagaacctcgcgatggtccgcgagaccgtcgcctacctgcgg
tcccagggccgccgggtcttcctcgactgcgagcacttcttcgacggctaccgcgccaac
gcggactacgccaagcaggtcgtctccgccgcccacgaggcgggcgccgaggtggtgatc
ctctgcgacaccaacggcggcatgctccccggccagatcgacgcggtggtccgcaccgta
ctggccgacaccggcgcccggctgggcatccacgcccaggacgacaccggctgcgcggtc
gccaacaccctcgccgccgtggacgcgggcgccacccacgtccagtgcacggccaacggc
tacggcgagcgggtgggcaacgccaacctcttcccggtcgtcgcggccctggagctcaag
tacggccgccgggtgctgccggagggcgccctggaggagatgacccggatctcgcacgcg
atcgccgaggtcgtcaatctgacgccgtccactcaccagccctatgtgggcgtatccgcc
ttcgcccacaaggccggactgcacgcctccgcgatcaaggtcgacccggatctgtaccag
cacatcgaccccgagcgggtcggcaacaccatgcggatgctcgtctccgacatggccggc
cgggcgtcgatcgagctcaaggggaaggagctgggcatcgacctcggtgacgaccgcgcc
ctggtgggccggatcgtcgagcgggtcaaggagcgcgagctcgcgggctacacctacgag
gccgccgacgcctccttcgagctgctgctgcgccaggaggtcgacggccgtccccgccgc
tacttccgggtcgagtcctggcgggcgatcgtcgaggaccgcccggacggcacccacgcc
aacgaggccaccgtgaagctgtgggccaagggcgagcgcatcgtcgccacggcggaggga
aacggcccggtcaacgccctggaccgggcgctgcgggtggggctggagcggatctacccg
cagttggcgaccatggagctggtggactacaaggtccgcatcctggaaggcaagcacggc
accgagtccacgacccgggtgctggtctccaccgcggacggccagggcgagtggtcgacg
gtcggcgtcggggagaacgtgatcgccgcgtcctggcaggccctggacgacgcctacgcc
tacgggctgctgcgggccggggtggacccgcaggagtga
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