Streptomyces viridifaciens: CP971_03955
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Entry
CP971_03955 CDS
T06960
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
svr
Streptomyces viridifaciens
Pathway
svr00300
Lysine biosynthesis
svr00550
Peptidoglycan biosynthesis
svr01100
Metabolic pathways
svr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
svr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CP971_03955 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CP971_03955 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CP971_03955 (murF)
Enzymes [BR:
svr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CP971_03955 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QEU98581
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Position
880028..881416
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AA seq
462 aa
AA seq
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MVPMTLHEIAQAVGGALHDAVDPVAVVDRPGVIDSRLVEPGALFIALPGEHTDGHRFAEA
AVRAGATGVLAARPVGVPAIVVADVQDAMGALARAVLDRLKAPTVIGLTGSAGKTSTKDL
LAQVLETIDTTVATPLSYNGEIGLPLTVFRADEDTRLLVLEMGARGAGHIKYLTGIVPPK
VGLVLNVGTAHVGEFGGGKESIAAAKGELVEALPADGLAVLNADDPYVMSMAPRTVAPVL
TFGIKTGDVRACGIELDAAGRPSFTLTYRGQSAPVKLGLHGAHHVSNATAAAAVAVGLGA
GLRQTADALAGARQLTPGRMDITDRPDGVTVIDDAFNANPESMAAALAALTAIAGGRRTV
AVLGEMRELGAQSGDHHARLGRLVADSGIHHLIAVGDQDAALVHATAAEGGVNATLVPDR
DAALDLLLAYLKPGDVVLVKGSHSTGLEETALRLAEPDATRG
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
gtggtccccatgaccctgcacgagatcgcccaggccgtcgggggcgccctgcacgacgcc
gtcgatccggtcgcggtggtggaccggcccggggtcatcgactcgcggctggtggagccg
ggagcgctgttcatcgcgctgccgggcgagcacacggacgggcaccggttcgccgaggcc
gctgtccgcgccggggcgacgggcgtgctggcggcccggccggtcggggtgccggcgatc
gtggtggcggacgtccaggacgcgatgggcgcgctggcccgcgcggtgctcgaccggctg
aaggcaccgaccgtgatcgggctgaccggctcggccggaaagaccagcaccaaggatctg
ctggcccaagtgctggagaccatcgacaccacggtggcaaccccgctgtcgtacaacggc
gagatcggcctgccgctgaccgtcttccgggcggacgaggacacccgcctgctggtgctg
gagatgggagcgcgcggtgccgggcacatcaagtacctgacggggatcgtcccgccgaag
gtcggcctggtgctgaacgtcgggaccgcgcacgtgggcgagttcggcggcgggaaggag
tcgatcgccgccgcgaagggcgaactcgtcgaggccctgcccgccgacggcctggcggtg
ctcaacgccgacgacccctacgtcatgtcgatggccccccgcaccgtcgcgcccgtcctg
accttcggcatcaagaccggggacgtccgcgcctgcggcatcgaactggacgccgcaggc
cggccgtcgttcaccctcacgtaccgcggccagagcgcccccgtgaagctggggctgcac
ggcgcccaccacgtctccaacgccaccgcagccgccgcggtggccgtcggactgggcgcc
ggcctgcggcagaccgccgacgcgctggccggcgcccggcagctgacgcccggccggatg
gacatcactgaccgccccgacggcgtgacggtcatcgacgacgcgttcaacgccaacccg
gaatccatggccgccgccctcgcggcactgaccgccatcgccggtgggcgaaggacggtc
gcggtgctgggcgagatgcgcgaactcggcgcgcagtccggggaccaccacgcgcggctc
ggccggctcgtcgccgacagcggcatccaccacctgatcgcggtcggcgaccaggatgcc
gccctggtccacgccacggctgccgaaggcggcgtcaacgccacgctggtccccgaccgc
gacgccgccctcgacctgctgctggcgtacctgaagcccggcgacgtggtgctggtgaag
ggttcccacagcaccgggctggaggagaccgcgctgcgcctggccgaacccgacgccaca
cgcggctga
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