Streptomyces viridifaciens: CP971_24635
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Entry
CP971_24635 CDS
T06960
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
svr
Streptomyces viridifaciens
Pathway
svr00300
Lysine biosynthesis
svr00550
Peptidoglycan biosynthesis
svr01100
Metabolic pathways
svr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
svr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CP971_24635 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CP971_24635 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CP971_24635 (murF)
Enzymes [BR:
svr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CP971_24635 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NUDIX-like
GGDEF_2
DUF2126
Motif
Other DBs
NCBI-ProteinID:
QEV02003
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Position
5568161..5569564
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AA seq
467 aa
AA seq
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MIALTLAEVAAAVGGTLDGADPDTVVTGPVEVDSRKVSPGGLFAAFVGENVDGHDYAATA
VEAGAVAVLASRPVGVPAVLVDSVVEALGRLARTVVARAEGTAVVALTGSAGKTSTKDLI
AQLLRRHGETVFPPGSLNNEIGHPMTALRVEESTRHLVMEMGARHKGDIEYLTSITPPRI
GLVLNVGTAHVGEFGSQEAIAEAKGELVEALPADGAAILNADDRLVRAMASRTKAKVVLF
GESPDAHVRATDVRLDATGRPSFTLTTPAGSAPVQLRLYGEHHVSNALAAAAVATELGMT
VDDTAAALGEAGALSRWRMEVVDRADGVTVVNDAYNANPDSMRAALRALVSMGGRGPERR
RTWAVLGEMRELGEDSLAEHDAIGRLAVRLDVTKLVAVGGREAACMELGARNEGSWGEES
VLVSDADAAVELLRSQLRPGDVVLVKASRSVGLEKVAEALLADGAAR
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcactgaccctcgccgaggtggccgccgccgtcggaggcaccctggacggcgcc
gacccggacaccgtggtcaccggcccggtcgaggtcgactcgcggaaggtgagccccggc
ggcctgttcgcggccttcgtcggcgagaacgtggacggccacgactacgccgccacggcg
gtcgaggccggcgccgtcgcggtgctggcctcccgcccggtcggcgtgcccgccgtcctg
gtcgacagtgtggtggaggcgctcggcaggctggcccggaccgtggtcgcccgcgccgag
ggcaccgccgtggtcgcgctgaccggctcggccggcaagaccagcaccaaggacctgatc
gcccagctgctccggcgccacggcgagaccgtcttcccgcccggctcgttgaacaacgag
atcggccacccgatgaccgcgctgcgggtcgaggagagcacccggcacctggtgatggag
atgggcgcccggcacaagggcgacatcgagtacctcacctcgatcaccccgccgcggatc
ggcctggtgctcaacgtcggcaccgcccacgtcggcgagttcggctcccaggaggcgatc
gccgaggccaagggcgagctggtcgaggcgctgcccgccgacggcgccgcgatcctgaac
gcggacgaccggctggtgcgcgcgatggcctcgcgcaccaaggcgaaggtggtcctgttc
ggggagtccccggacgcccacgtccgggcgaccgacgttcgcctggacgccaccggtcgg
ccgtcgttcacgctcaccaccccggccggttccgcgcccgtgcagctgcgcctgtacggt
gagcaccacgtctcgaacgccctcgccgccgccgcggtggcgacggagctcgggatgacc
gtcgacgacaccgcggcagccctgggcgaggcgggtgcgctgtcccgctggcgcatggag
gtcgtcgaccgggccgatggtgtcaccgtcgtcaacgacgcctacaacgcgaaccccgac
tcgatgcgggccgcgctgcgggcgctggtctcgatgggcggccgcggtccggagcgccgc
cgcacctgggcggtgctcggcgagatgcgggagctcggcgaggacagcctggccgagcac
gacgccatcgggcggctcgccgtccggctggacgtcaccaagctggtggcggtcggcgga
cgcgaggcggcctgcatggaactcggcgcgaggaacgaaggttcgtggggtgaggagtcg
gtgctggtgtccgacgcggacgcggcggtcgaactgctgcgcagtcagcttcggccgggg
gatgtggtcctggtgaaggcgtcccgttcggtggggctggagaaggtggccgaggccctc
ctggcggacggtgctgcccgatga
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