Sciurus vulgaris (Eurasian red squirrel): 306655560
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Entry
306655560 CDS
T11892
Symbol
JAK1, ACX6B4_017992
Name
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
svul Sciurus vulgaris (Eurasian red squirrel)
Pathway
svul01521
EGFR tyrosine kinase inhibitor resistance
svul04151
PI3K-Akt signaling pathway
svul04217
Necroptosis
svul04380
Osteoclast differentiation
svul04550
Signaling pathways regulating pluripotency of stem cells
svul04620
Toll-like receptor signaling pathway
svul04621
NOD-like receptor signaling pathway
svul04630
JAK-STAT signaling pathway
svul04658
Th1 and Th2 cell differentiation
svul04659
Th17 cell differentiation
svul05140
Leishmaniasis
svul05145
Toxoplasmosis
svul05152
Tuberculosis
svul05160
Hepatitis C
svul05161
Hepatitis B
svul05162
Measles
svul05163
Human cytomegalovirus infection
svul05164
Influenza A
svul05165
Human papillomavirus infection
svul05166
Human T-cell leukemia virus 1 infection
svul05167
Kaposi sarcoma-associated herpesvirus infection
svul05168
Herpes simplex virus 1 infection
svul05169
Epstein-Barr virus infection
svul05171
Coronavirus disease
svul05200
Pathways in cancer
svul05203
Viral carcinogenesis
svul05212
Pancreatic cancer
svul05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
svul00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
306655560 (JAK1)
04151 PI3K-Akt signaling pathway
306655560 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
306655560 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
306655560 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
306655560 (JAK1)
04621 NOD-like receptor signaling pathway
306655560 (JAK1)
04658 Th1 and Th2 cell differentiation
306655560 (JAK1)
04659 Th17 cell differentiation
306655560 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
306655560 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
306655560 (JAK1)
05203 Viral carcinogenesis
306655560 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
306655560 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
306655560 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
306655560 (JAK1)
05161 Hepatitis B
306655560 (JAK1)
05160 Hepatitis C
306655560 (JAK1)
05171 Coronavirus disease
306655560 (JAK1)
05164 Influenza A
306655560 (JAK1)
05162 Measles
306655560 (JAK1)
05168 Herpes simplex virus 1 infection
306655560 (JAK1)
05163 Human cytomegalovirus infection
306655560 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
306655560 (JAK1)
05169 Epstein-Barr virus infection
306655560 (JAK1)
05165 Human papillomavirus infection
306655560 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
306655560 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
306655560 (JAK1)
05140 Leishmaniasis
306655560 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
306655560 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
svul01001
]
306655560 (JAK1)
Enzymes [BR:
svul01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
306655560 (JAK1)
Protein kinases [BR:
svul01001
]
Non-receptor tyrosine kinases
JAK family [OT]
306655560 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
306655560
NCBI-ProteinID:
XP_078986263
LinkDB
All DBs
Position
1:complement(53345077..53483006)
Genome browser
AA seq
1155 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKAEVNQVAPEPGVEVTFYLPDREPLRLGSGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITIDDKMSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKAPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WLHSNDSGNVLYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIQE
EWNNFSYFPEITHIVIKESLVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAHH
YLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGNEEGMYVLRWSCTDFDNILMTVTC
FEKSEVLGTHKQFKNFQIEVQKGRYSLHGSDRNFPSLEGLMSHLKKQILRTDNISFVLKR
CCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGDHLGRGTRTHIYSGTL
LDYKDDEGAAEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDVE
NIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLLL
AREGIDSEIGPFIKLSDPGIPVTVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGTT
LWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAIM
RDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTG
EQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSG
SLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDF
GLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSES
SPMALFLKMIGPTQGQMTVTRLVNTLKEGKRLPCPPNCPDQVYQLMRKCWELQPSNRTTF
QSLIEGFEALLKYEA
NT seq
3468 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaaggcggaggtgaatcaggtggcccctgagccaggggtggaagtgaccttc
tatcttccagacagggagcccctccggctgggcagtggagagtacacagcagaggagctg
tgcatcagggctgcgcaggaatgctgtatctctcctctatgccacaacctctttgccttg
tacgatgagaacaccaagctctggtatgctccgaaccgcaccatcaccattgatgacaag
atgtcactccgacttcactaccgcatgaggttctatttcacaaactggcatgggaccaat
gacaatgagcagtctgtatggcgacattcaccaaagaagcagaaaaatggctacgagaag
aaaaaggctccagatgcaacccctctccttgatgccagctcactggagtacctgtttgct
cagggacagtatgatttggtcaaatgcctggctcccattcgggaccccaagactgagcag
gatgggcatgatattgagaacgagtgcctggggatggctgtcctggccatctcacactat
gccatgataaagaagatgcagttgccagaacttcccaaggacatcagctacaagcgatat
attccagaaacgttgaataaatccatcagacagaggaaccttcttaccaggatgcggata
aacaatgttttcaaggatttcctaaaggaatttaacaacaagacaatttgtgacagcagt
gtgtccactcatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggggctgaaatatttgagacttctatgttattgatttcatcagaaaatgaaatgaat
tggcttcattcgaatgacagtggaaatgttctctatgaagtgatggtaactggaaatctt
ggaatccagtggcggcagaaaccaaatgttgttcctgttgaaaaggaaaaaaataaactg
aagcggaaaaaactggaaaataaacacaagaaggatgaggagaaaaacaaaatccaggaa
gaatggaacaatttttcttatttccctgaaatcactcacattgtaatcaaggagtcttta
gtcagcattaataagcaggacaacaaaaaaatggaactgaagctttcttcccatgaggag
gccttgtcctttgtgtccctggttgatggctacttccgactcacagctgatgcccatcat
tacctctgcaccgatgtggctcccccattgatagtccacaatatacagaatggctgtcac
ggtccaatctgcacagaatatgccatcaataagctgcggcaagaagggaacgaggagggg
atgtacgtgctgaggtggagctgcaccgactttgacaacatcctcatgactgtcacctgc
tttgaaaagtctgaggtgctgggtacccataagcagttcaagaattttcagatcgaggta
cagaagggccgctacagcctgcatggctcggaccgcaacttccccagcctggaaggcctc
atgagccacctcaagaagcagatcctacgcacggacaacatcagctttgtgctgaagcgc
tgctgccaacccaagcctcgagaaatctccaatctgttggtggccaccaagaaggcccag
gagtggcagcctgtctaccccatgagccagctgagttttgatcggatcctcaagaaagat
attgttcaaggtgatcaccttggcagaggcacaagaacacacatctactctgggaccctg
ctggattacaaggacgatgaaggggctgctgaagagaagagaataaaagtgatactcaaa
gtcttagaccccagccacagggacatttctctggccttctttgaagcagctagcatgatg
agacaggtctcccacaaacacatcgtgtacctctatggcgtctgtgtccgagacgtggaa
aatatcatggtggaggagtttgtggaggggggacccctggatctcttcatgcaccggaaa
agcgatgtcctcactacaccatggaagttcaaagttgccaaacagctggccagtgccctg
agttacttggaagataaagacctggtccatggaaatgtgtgtaccaaaaatctcctcctg
gcccgtgagggcattgacagtgaaattggcccattcatcaagcttagtgaccctggaatc
cctgtcactgtactgtcaaggcaagagtgcatagaacgaatcccatggattgctcccgag
tgtgttgaagactctaagaacctgagcgtggctgctgacaaatggagctttggaaccaca
ctctgggaaatctgctacaatggcgagatccccctgaaagataagacactgattgagaaa
gagagattctatgaaagccggtgcagaccagtgacaccatcgtgcaaggagctggccgac
cttatgactcgctgcatgaactatgaccccaatcagagacccttcttccgagccatcatg
agggacattaacaagcttgaagagcagaatccagacattgtttcagaaaaaaaaccagca
actgaggtggatcccacacattttgaaaagcgcttcctaaagaggatccgcgacttggga
gagggccactttgggaaagttgagctctgcaggtatgacccagagggggacaatacagga
gagcaagtagctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgatctg
aagaaggaaatagaaatcttaaggaacctctatcatgagaacattgtgaagtacaaagga
atctgcactgaagatggaggaaatggtattaagcttatcatggagtttctgccttctgga
agccttaaggaatatcttccaaagaataagaacaaaattaaccttaaacagcagctgaaa
tatgctgttcagatttgtaaggggatggactatttgggttctcggcaatatgttcaccgg
gacttagcagcaagaaatgtccttgttgagagtgaacaccaagtgaaaattggagacttt
ggtttaaccaaagcaattgaaacggataaggagtactacaccgtcaaggacgaccgggac
agccctgtgttttggtacgcgccagaatgtttaattcagtgtaaattttatattgcctct
gatgtctggtcttttggagtgaccctgcatgagctgcttacttactgtgattcagagtct
agtcccatggctttgttcctgaaaatgataggcccaactcaaggccagatgaccgtaaca
agacttgtgaacacgctgaaagaaggaaaacgtttgccatgtccgcctaactgtcctgat
caggtttatcaacttatgagaaaatgctgggaattacagccatccaatcggacaaccttt
cagagccttatcgaaggatttgaagcacttttaaaatacgaagcatga
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