KEGG   MODULE: swd_M00125
Entry
swd_M00125        Pathway   Module                                 
Name
Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
Definition
(K01497,K14652) ((K01498 K00082),K11752) (K22912,K20860,K20861,K20862,K21063,K21064)
(K02858,K14652)
K00794 K00793 ((K20884 K22949),K11753)
Diagram
swd_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD
swd_M00125

Class
Pathway modules; Metabolism of cofactors and vitamins; Cofactor and vitamin metabolism
Pathway
swd00740  Riboflavin metabolism
swd01240  Biosynthesis of cofactors
swd01100  Metabolic pathways
swd01110  Biosynthesis of secondary metabolites
Organism
Shewanella woodyi [GN:swd]
Gene
Swoo_0490  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K20862]
Swoo_1290  riboflavin biosynthesis protein RibF [KO:K11753]
Swoo_1382  riboflavin biosynthesis protein RibD [KO:K11752]
Swoo_1383  riboflavin synthase, alpha subunit [KO:K00793]
Swoo_1384  3,4-dihydroxy-2-butanone 4-phosphate synthase [KO:K14652]
Swoo_1385  6,7-dimethyl-8-ribityllumazine synthase [KO:K00794]
Swoo_2495  riboflavin synthase, alpha subunit [KO:K00793]
Swoo_3046  GTP cyclohydrolase II [KO:K01497]
Swoo_4764  3,4-dihydroxy-2-butanone 4-phosphate synthase [KO:K02858]
Reaction
R00425  
R03459  
R03458  
R07280  
R07281  
R04457  
R00066  
R00549  
R00161  
Compound
C00044  GTP
C01304  2,5-Diamino-6-(5'-phosphoribosylamino)-4-pyrimidineone
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C04454  5-Amino-6-(5'-phosphoribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C00199  D-Ribulose 5-phosphate
C15556  3,4-Dihydroxy-2-butanone 4-phosphate
C04332  6,7-Dimethyl-8-(1-D-ribityl)lumazine
C00255  Riboflavin
C00061  FMN
C00016  FAD
Reference
PMID:10940330
  Authors
Bacher A, Eberhardt S, Fischer M, Kis K, Richter G
  Title
Biosynthesis of vitamin b2 (riboflavin).
  Journal
Annu Rev Nutr 20:153-67 (2000)
DOI:10.1146/annurev.nutr.20.1.153
Reference
PMID:27822970
  Authors
Garcia-Angulo VA
  Title
Overlapping riboflavin supply pathways in bacteria.
  Journal
Crit Rev Microbiol 43:196-209 (2017)
DOI:10.1080/1040841X.2016.1192578
KO module
M00125
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