Streptomyces xiamenensis: SXIM_10280
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Entry
SXIM_10280 CDS
T03904
Name
(GenBank) 6-diaminopimelate-D-alanyl-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sxi
Streptomyces xiamenensis
Pathway
sxi00300
Lysine biosynthesis
sxi00550
Peptidoglycan biosynthesis
sxi01100
Metabolic pathways
sxi01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sxi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SXIM_10280
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SXIM_10280
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SXIM_10280
Enzymes [BR:
sxi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SXIM_10280
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PhageMin_Tail
DUF561
HTH_53
Motif
Other DBs
NCBI-ProteinID:
AKG42412
UniProt:
A0A0F7FQY0
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All DBs
Position
complement(1126967..1128406)
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AA seq
479 aa
AA seq
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MIPLPVAELVTVVRGTPHDIPEPPPPVTGPVVIDSREAVPGALFAALPGDRVDGHDFADR
AVAAGAAVVLATRRLGAGVPTVVVDDVTEALGALAQHTVRRLGTPVIALTGSSGKTSTKD
LTAQLLERVGPTVYTAESFNNEIGLPLTALRLTGETRHLLLEMGARGIGHIRYLTTLAPP
TIGMVLNVGTAHLGEFGSREAIARAKGEIVEGLPPAEEGGVAILNADDPLVRAMSERTRA
RTVFFGEAEEADIRAEDVHLTPQGRPAFRLKTPTGYADVTMRLYGEHHVSNALAAAAVAH
EVGMSAAEIAQTLSAAGPLSKWRMEVTERADGVTIVNDAYNANPDSMRAALRALAAMGGA
AGAGGGRTWAVLGAMAELGDDALAEHDAVGRLAVRLNVSKLVSVGGQEAAWLDMGAKNEG
SWGEESVHVSDASAAVELLRGQLRPGDVVLVKASRSVGLEQVAIALAGDVDGVGEVAAR
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
gtgatccctcttcccgttgctgagctcgtcacggtcgtacggggcaccccgcacgacata
ccggagccgccacctcccgtcaccgggcccgtggtcatcgactccagggaggccgtcccc
ggcgccctgttcgccgccctgccgggcgaccgcgtcgacggccacgacttcgccgaccgg
gcggtcgccgccggcgcggccgtcgtcctggccacccgccgcctcggcgccggggtgccc
acggtcgtggtcgacgacgtcaccgaagcgctgggtgccctcgcccagcacacggtgcgc
cggctcggtaccccggtcatcgccctcaccggctcctccggcaagacgagtaccaaggac
ctcaccgcccagctgctggagcgcgtgggccccacggtctacaccgccgaatcgttcaac
aacgagatcggcctgccgctgaccgcgctgcgcctgaccggggaaacccgtcatctcctg
ctggagatgggcgcccgcgggatcggccacatccgctatctcacgacgctggccccgccc
accatcggcatggtgctgaacgtgggcaccgcccacctgggcgagttcggcagccgggag
gcgatcgcgcgggccaagggcgagatcgtcgaagggctgccgccggccgaggagggcggg
gtggcgattctcaacgccgacgaccccctggtgcgcgcgatgagcgagcgcacccgcgcc
cgtaccgtgttcttcggggaggccgaagaggcggacatccgcgccgaagacgtccatctg
acccctcagggacgccccgcgttccgcctcaagacccccaccgggtacgccgacgtgacc
atgcggttgtacggtgagcaccatgtgtcgaacgcgcttgccgctgcggctgttgcgcat
gaggtaggcatgtccgctgcggagatcgctcaaacgctttccgccgcgggcccgctctcg
aagtggcggatggaggtcaccgagcgagcggacggcgtgacgatcgtcaacgacgcctac
aacgccaacccggattccatgcgggccgccctgcgcgcactcgccgccatgggcggcgcc
gccggagccgggggaggccgtacgtgggcggtgctcggcgccatggccgagctgggggac
gacgcgctcgccgagcacgacgccgtcggacggctcgccgtccggctcaacgtcagcaag
cttgtgtccgtgggcggtcaagaggccgcctggctggacatgggcgccaagaacgagggt
tcgtggggtgaggagtcggtgcacgtgtccgacgcttcggcagcggtggagctgctgcgc
ggtcagttgcggccgggagatgtggtgttggtgaaggcgtccaggtcggtgggcctggag
caggtcgccatcgcactggccggcgacgtcgacggcgttggtgaggtcgccgcccgatga
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