Shewanella xiamenensis: MKD32_05695
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Entry
MKD32_05695 CDS
T08228
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sxm
Shewanella xiamenensis
Pathway
sxm00260
Glycine, serine and threonine metabolism
sxm00261
Monobactam biosynthesis
sxm00270
Cysteine and methionine metabolism
sxm00300
Lysine biosynthesis
sxm01100
Metabolic pathways
sxm01110
Biosynthesis of secondary metabolites
sxm01120
Microbial metabolism in diverse environments
sxm01230
Biosynthesis of amino acids
Module
sxm_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sxm_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sxm_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sxm00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MKD32_05695 (thrA)
00270 Cysteine and methionine metabolism
MKD32_05695 (thrA)
00300 Lysine biosynthesis
MKD32_05695 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MKD32_05695 (thrA)
Enzymes [BR:
sxm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MKD32_05695 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MKD32_05695 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
DUF1131
Motif
Other DBs
NCBI-ProteinID:
UML94806
LinkDB
All DBs
Position
1298640..1301108
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AA seq
822 aa
AA seq
DB search
MKVMKFGGTSLANWQRFSMAADIVAKAAKAEPVATVLSAPATVTNALLEMVDVAVKGEDY
SPVIQHVERVFTSLYQDAVSSGLSSSQSEVLFAGLSAQLARWQDRLRGIKLLQECPDGIR
AEIVVVGERLSAALMEQVMLAKGITSAQLDPRELFLGRGRPLESVVDIAVSKPRFKNLAL
DEKRVWVMPGFTAADEDGKVVTLGRNGSDYSAAVLAACLDASSCEIWTDVDGVYNTDPRV
VTDAKLLSQLSYQEAMELSYFGAKVLHPKTIAPIAQFHIPCYIKNSFNPDAPGTLVSNQA
DESGLQVKAISNLDNQTMFDVSGPGMKGMVGMASRTLAAISRSGVSVSLITQSSCEYSIS
FCVATSESDKVKSALEQEFELEIKSDLLEPIEMRHDLAIVSLIGDGMRTHKGVAARFFQA
LAQASVNIIAIAQGSSERSISTVIEQRKTKHAVAACHQGFFDVQQYLDVFLVGCGNVGAG
LLEQIKHQASVLKEQHISIRVCGIVNSSKMLLDSAGIDLNNWQNLLADIQQPSDLPALLA
WVKEQQLLNPVLVDCTSSDQVSNQYLEVMNAGMHVVTPNKKANTRDYAYYQALRQTALKQ
RRQFLYETNVGAGLPVIDNLKKLLFAGDKLHKFNGILSGSLSFIFGKLDEGMSLSEATKL
AREKCFTEPDPRDDLSGMDVARKVLILAREVGLKLELSDIVVDSVLPDDFDDSGDVESFM
ARLPEADAAIAARVAEAKAQGKVLRYVGQIEEGACYVRITEVDATDPLYSVKGGENALAF
YSRYYQPIPFVLRGYGAGTEVTAAGAFADVLRTLNWTREVSV
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtgatgaaatttggtggtacctcgcttgcaaattggcagcgattttcaatggcg
gcggatatcgtggccaaggcagcgaaagctgagccggtggcgacagtgctctctgcgcct
gcaacagtgacaaacgctctgctagaaatggtcgatgtggcggtgaaaggggaagattat
tcgccagtcattcaacatgttgaacgggtgtttacctcgctctatcaagatgcggtcagt
tctggactctcaagcagtcaaagcgaagtgttgttcgccggactaagcgcgcagcttgcg
cgttggcaggacagattacgcggtattaagctgctacaggaatgccctgatggtattcgc
gccgagattgtggttgtgggcgagcgtttgtctgctgcgttgatggagcaagtcatgctg
gccaaaggcatcacttcggcgcagctggacccacgtgagctgtttttaggccgtggtcgt
ccgctcgagtccgtggtggatattgccgtcagtaaaccgcgattcaaaaatcttgccctc
gatgagaagcgcgtttgggttatgcctggctttaccgccgccgatgaagacggcaaggtc
gtgaccttaggccgtaacggctcagattactccgctgccgtgctggccgcttgtttagat
gcttcaagttgtgagatttggaccgacgttgacggcgtatacaacacagatcctcgggtt
gtcaccgatgctaagttgttgtcacagctaagttatcaagaggcgatggagctgtcttac
tttggcgctaaggtgctgcatcctaaaaccattgcgcctatcgcccagttccatattccc
tgttatatcaagaacagttttaaccccgatgcgcccggcactctggtatcgaatcaggcc
gatgaaagcggtttgcaggtgaaggccatttctaatctggataatcaaaccatgtttgat
gtatcaggccccggcatgaagggcatggtcggcatggcgagccgcacactggcggcgatt
tcccgtagtggtgtttccgtgtcactcatcacccagagctcttgcgaatacagcatcagc
ttttgtgtggcgaccagtgagtccgacaaggtgaagtcggcgctagagcaggaatttgag
ttagaaatcaaaagtgacttactcgagccaatcgaaatgcgccatgacttggcaattgtc
tccttgatcggtgatggaatgcgtacccataaaggtgtggcagcacggttcttccaagcg
ttagcgcaggcgagtgtgaatatcatcgcgattgcccaaggctcctccgagcgttctatt
tcaacggtgatcgaacagcgtaagaccaaacatgcggtcgccgcctgtcatcaaggcttt
ttcgatgtgcagcagtatttggatgtgtttttagtgggttgtggcaatgttggcgcaggc
ttactcgagcaaatcaaacatcaggcgagtgtgttaaaagagcagcacattagcatacgt
gtctgcggcatagtcaattcaagcaagatgttactcgatagtgcgggtatcgatttaaac
aattggcaaaacctgcttgccgacattcagcagccaagcgatcttcctgcgctattggct
tgggtgaaagaacaacaattattaaaccctgtgctggtggattgtacttcaagcgatcaa
gtatcgaaccagtatttagaggtgatgaacgcgggcatgcacgtggtgacgcccaataaa
aaggctaacactcgcgattacgcctattaccaagctttgcgtcaaacagcattaaagcaa
cgtcggcagtttctgtatgagaccaacgtgggcgcaggattacccgttatcgataacttg
aaaaaactgttattcgccggtgataaattgcacaagtttaatggcattttgtcaggctcc
ttatcctttatcttcggtaaactcgatgagggtatgtcactttctgaggcgactaaactg
gcgcgggaaaaatgctttaccgagcccgatccccgtgatgatttaagtggtatggatgtg
gcgcgtaaagtgctgattttggcccgtgaagtgggtttgaaacttgagctaagtgatatc
gttgtcgactcagtcttacctgacgattttgatgattcaggcgatgtggaaagttttatg
gcgcgtttacccgaggccgatgctgcgattgcggcgcgagtggcggaggcgaaagcgcag
ggtaaagtgctgcgttatgtggggcagattgaagaaggcgcgtgctatgtgcgtatcacc
gaagtcgatgcaaccgatccgctctatagcgtaaaaggcggtgaaaatgccttggcattc
tacagccgttattatcagccgattccctttgtgttgcgtggatatggtgcgggcacagaa
gtgactgcggcaggtgcctttgccgatgtattaagaaccttaaattggactcgtgaggtg
agtgtatga
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