Streptomyces xanthii: IAG42_04095
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Entry
IAG42_04095 CDS
T07861
Symbol
egtA
Name
(GenBank) ergothioneine biosynthesis glutamate--cysteine ligase EgtA
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
sxn
Streptomyces xanthii
Pathway
sxn00270
Cysteine and methionine metabolism
sxn00480
Glutathione metabolism
sxn01100
Metabolic pathways
sxn01240
Biosynthesis of cofactors
Module
sxn_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
sxn00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
IAG42_04095 (egtA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
IAG42_04095 (egtA)
Enzymes [BR:
sxn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
IAG42_04095 (egtA)
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Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
QNS02886
UniProt:
A0A7H1B2D1
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Position
835395..836684
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AA seq
429 aa
AA seq
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MTEGDCTTLGDLVTETEAEALVQGICFKTGPPRAVGVELEWIVHETHRPRLPLPPERLDA
AYAALRALPLSSALTVEPGGQLELSSLPAATLTECVSAVQADLTAVRTALRAHGLVLAGH
GTDPWRPPRRLLRRPRYDALEASLDRAGPAGRSMMCSSASVQVCLDAGYEEPGPLGYARR
WVLGHLLGAVLVAAFANSPMLSGRPTGWRSTRQLLWARIDAGRSAAPSPDGEPREAWARR
VLDAPVMCVRSADGPWEVPEGLTFRDWARTGEPRRPTRDDLDYHLTTLFPPVRPRGHLEL
RMIDAQPGEDGWLVPLAVTTALFDDPQAAETAYRAVKPLAERAGERPAPHNPLWRDAARL
ALTDPELREAATACFAAALEALPRLGAGAEVRRAVEDFHRRYVLRGRCPADDVLDPLTQP
PVQGRTVRS
NT seq
1290 nt
NT seq
+upstream
nt +downstream
nt
atgaccgagggagactgtacgacgctcggtgacctggtcaccgagaccgaggcggaggcc
ctggtacagggcatctgcttcaagaccggcccaccgcgcgcggtgggtgtggagctggag
tggatcgtccacgagacgcaccgcccccgcctcccgttaccgcccgaacggctcgacgcg
gcctatgccgcgctgcgcgccctgccgctgagctcggcgctcacggtggagcccggcggc
cagctggagctcagttcgctccccgccgccaccctgacggaatgcgtctcggccgtacag
gccgatctgaccgccgtccgcaccgcactccgcgcccacggcctcgtcctggccggccac
ggcacggatccgtggcgcccgccccggcggctgctgcggcgcccccgctacgacgccctg
gaggcctccctcgaccgggcgggaccggccggccgctccatgatgtgttcctccgcgtcg
gtgcaggtgtgcctggacgccgggtacgaggagccgggtccgctggggtacgcgcggcgc
tgggtgctcggccatctgctgggcgccgtgctcgtcgcggccttcgccaactcaccgatg
ctgtcgggccgtccgacgggctggcggtcgacgcggcagctcctgtgggcgcggatcgac
gcgggccgttccgcggcgccgtccccggacggggagccgcgggaggcatgggcgcggcgg
gtgctcgacgcgcccgtgatgtgcgtgcgcagcgccgacgggccgtgggaggtgccggag
gggctgacgttccgggactgggcgcgcacgggggaaccgcgccggccgacccgcgacgat
ctcgactaccacctgacgacgctgttccctccggtgcgcccgcgcggccatctggaactg
cgcatgatcgacgcgcagccgggcgaggacggctggctggtgccgctcgcggtgacgacg
gcgctgttcgacgatccgcaggccgcggagaccgcgtaccgggcggtgaagccgctggcc
gagcgggccggggagcgtcccgctccgcacaatccgctgtggcgcgacgcggcccgtctg
gcgctgaccgatcccgagctgcgggaggcggcgacggcctgtttcgcggcggcgctcgag
gcgctgccccggctcggcgcgggcgcggaggtgcggcgggcggtcgaggacttccaccgc
cgctacgtgctgcgcggccgctgcccggccgacgacgtgctcgatccgctcacgcaaccg
cctgtccaggggaggaccgtccgctcatga
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