Streptomyces xanthii: IAG42_09875
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Entry
IAG42_09875 CDS
T07861
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sxn
Streptomyces xanthii
Pathway
sxn00290
Valine, leucine and isoleucine biosynthesis
sxn00660
C5-Branched dibasic acid metabolism
sxn01100
Metabolic pathways
sxn01110
Biosynthesis of secondary metabolites
sxn01210
2-Oxocarboxylic acid metabolism
sxn01230
Biosynthesis of amino acids
Module
sxn_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sxn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
IAG42_09875 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
IAG42_09875 (leuC)
Enzymes [BR:
sxn01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
IAG42_09875 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
IAG42_09875 (leuC)
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GFIT
Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QNS03907
UniProt:
A0A7H1B5A2
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Position
complement(2187243..2188667)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNAAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPMARPKTMAITVEGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGREHAPKGEDWDAAVAYWKTLKSDDDAVFDAEVVIKADELSPFVTWGTNPGQGAPL
SANVPDPASYEDASERLAAEKALEYMGLEAGQPLRDIKVDTVFVGSCTNGRIEDLRAAAE
ILKGRKVADGVRALIVPGSARVGLQAVSEGLDKVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPVAAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgcaagagcggccgccaggtgcggcggctcgacctcaccatcgcgacc
gaggatcacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcccgg
gtccagctggagacgctgcgcaagaacgccgcggagttcggcgtgcgcctgcactccctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggcccgcagctgggtctgacccagccc
ggcatgacggtcgtgtgcggtgactcccacacctccacgcacggcgcgttcggcggtctg
gccttcggcatcggcacctcgcaggtcgagcacgtgctggccacccagacgctgccgatg
gcccgccccaagaccatggccatcacggtcgagggcgagctgcccgagggcgtcaccgcc
aaggacctgatcctggcgatcatcgcccgcatcggcaccggcggcggccagggctacgtc
ctggagtaccgcggctccgccatcgagaaactgtcgatggaagcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctacctggagggccgcgagcacgcccccaagggcgaggactgggacgccgcggtcgcc
tactggaagacgctgaagtcggacgacgacgcggtcttcgacgccgaggtcgtcatcaag
gccgacgagctgtccccgttcgtcacctggggcaccaacccgggccagggcgccccgctt
tcggcgaacgtccccgaccccgcttcgtacgaagacgcctcggagcgcctggccgccgaa
aaggccctggagtacatggggttggaggccggccagccgctgcgcgacatcaaggtcgac
accgtattcgtaggctcctgcaccaacggccgcatcgaggacctgcgggccgccgccgag
atcctcaagggccgcaaggtcgccgacggtgtgcgcgcgctgatcgttcccggctccgcg
cgggtcggtctgcaggccgtctccgagggcctggacaaggtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctccatgtgcctgggcatgaacccggaccaactcgcgccc
ggcgagcgctccgcgtccacgtccaaccgcaacttcgagggccggcagggcaagggcggc
cgtacgcatctggtctcgccccaggtcgccgccgccaccgccgtgctgggccacctggcc
tcgcccgccgacctgtccgacgcccccgtcgccgctggagtctga
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