Streptomyces xanthii: IAG42_26195
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Entry
IAG42_26195 CDS
T07861
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sxn
Streptomyces xanthii
Pathway
sxn00300
Lysine biosynthesis
sxn00550
Peptidoglycan biosynthesis
sxn01100
Metabolic pathways
sxn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sxn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
IAG42_26195
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IAG42_26195
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IAG42_26195
Enzymes [BR:
sxn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
IAG42_26195
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2126
Motif
Other DBs
NCBI-ProteinID:
QNS06729
UniProt:
A0A7H1BDC4
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All DBs
Position
5811788..5813209
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AA seq
473 aa
AA seq
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MIALSLAEIASAVGGQTYDIPDESVRVTGPVVIDSRKVEAGSLFAAFAGERVDGHDYARQ
VVDQGAAAVLASRPVGVPAIVVDDVQAALGALARHVVARLGATLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSFNNEIGLPLTALSATDDTKFLVLEMGARGKGHIRYLTGLTPPRV
GLVLNVGTAHIGEFGGREQIAEAKGELVEALPADGTAILNADDPLVRAMASRTRAKVLLF
GEAADADVRAENVRLTENGQPAFSLHTPTGCSEVTLRLYGEHHVSNALAAAAVAHDLGMS
VEEIALALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALTAMGQARRAAG
GRTWAVLGQMAELGDESLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAIDLLRSELRPGDVVLVKASRSVGLESVAQALLDSGIDAGADAR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgcctcagccgtcggcgggcagacgtacgacata
ccggacgagtcggtccgggtcaccgggccggtcgtcatcgactcgcgcaaggtcgaggcc
ggcagcctgttcgcggcctttgcaggtgagcgggtcgacggccacgactacgcgcgccag
gtcgtcgaccagggagcggccgccgtcctggcgtcccgccccgtcggcgtgcccgcgatc
gtcgtcgacgacgtccaggccgcgctcggcgcgctcgcccggcacgtcgtggcccgcctc
ggcgcgacgctcgtcgcgctgaccggctcggccggcaagaccagcaccaaggacctcatc
gcccaggtgctgcggcgcaaggcccccacggtcttcacgcccggctcgttcaacaacgag
atcggcctgccgctgaccgccctctccgccacggacgacacgaagttcctcgtcctggag
atgggcgcccgcggcaagggccacatccggtacctcaccggcctcacccctcccagggtg
ggcctcgtcctcaacgtcggcaccgcgcacatcggcgagttcggcggccgcgagcagatc
gcggaagcgaagggtgaactcgtcgaggcgctgcccgccgacggcaccgcgatcctcaac
gcggacgacccgctggtgcgcgccatggcctcccgtacgcgggcgaaggtgctcctcttc
ggagaggccgccgacgccgacgtacgcgccgagaatgtccggctcacggagaacggacag
cccgccttcagccttcacacacccaccgggtgcagcgaagtgaccttgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgaccttggcatgtcc
gtggaggagatcgccctcgcgctctccgaggcgggcaccctgtcccgctggcggatggag
gtcaccgagcgtccggacggcgtcacgatcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccctgcgcgcgctcacggcgatgggccaggcccgacgggccgcgggg
ggccgtacgtgggcggtgctcgggcagatggccgagctcggcgacgagtcgctggccgag
cacgacgccgtcggacggctcgccgtccggctcaacgtcagcaagctcgtggcagtcggg
ggcagggaagcgtcctggttgcaactgggcgcctataacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcgatcgacctgttgcgcagcgagctgcgcccg
ggagacgtcgtgctcgtgaaggcatccaggtcggtgggcctggagagcgtggcacaggcg
ctgctcgacagcggcatcgacgccggggctgatgcccgatga
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