Streptomyces xanthophaeus: KPP03845_102330
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Entry
KPP03845_102330 CDS
T08962
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sxt
Streptomyces xanthophaeus
Pathway
sxt00300
Lysine biosynthesis
sxt00550
Peptidoglycan biosynthesis
sxt01100
Metabolic pathways
sxt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sxt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KPP03845_102330 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KPP03845_102330 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KPP03845_102330 (murF)
Enzymes [BR:
sxt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KPP03845_102330 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
Motif
Other DBs
NCBI-ProteinID:
WCD85988
LinkDB
All DBs
Position
complement(2508942..2510366)
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AA seq
474 aa
AA seq
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MIDLSLAEIADITGGRPHDIPDPSVRITGPVVIDSRQVEAGSLFAAFDGEHVDGHDYAVR
AVEAGAAAVLAARPVGVPAVVVPDVEKALGALARAVVQRLGTDVVALTGSAGKTSTKDLI
AQVLQAHAPTVWTPGSLNNEIGLPLTALKATAETRHLVLEMGARGIGHIAYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPAEAEGGVAVLNADDPLVRAMSGRTKART
VLFGEAEDADVRATEVRMAPGGQPAFTLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHVL
GMSVSEIATALSGAGTLSRWRMEVTERADGVTIVNDAYNANPESMRAALRALAAMGGSAR
ANGGRTWAVLGPMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVVVSDAQAAVDLLRSELRPGDVVLVKASRSIGLERVALALLEREGEVADR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgacctctccctcgccgagatcgccgacatcaccggcgggcggccccacgacata
ccggatccgtcggtgcggatcaccgggccggtcgtcatcgactcccgccaggtggaggcc
ggcagcctcttcgccgccttcgacggcgagcacgtcgacggccacgactacgcggtgcgc
gcggtcgaggcgggcgccgcggccgtcctcgcggcccggccggtcggcgtacccgccgtc
gtcgtccccgacgtcgagaaggcgctcggcgccctcgcccgggccgtcgtccagcgcctg
ggcaccgacgtggtggccctgaccggttccgccgggaagacctccaccaaggacctcatc
gcgcaggtgctccaggcccacgctcccacggtgtggaccccgggctccctcaacaacgag
atcggcctgccgctcaccgcgctgaaggccacggcggaaacccggcacctggtactggag
atgggggcccgcggaatcggccacatcgcgtacctgaccggcctgaccccgccccgcatc
ggcctcgtcctcaacgtcgggaccgcccacatcggcgagttcggcggccgcgaacagatc
gcccaggccaagggggaactggtcgaggccctgccggccgaggccgagggcggagtcgcc
gtcctgaacgccgacgacccgctggtgcgcgcgatgtccgggcgcacgaaggcccgtacg
gtcctcttcggagaggccgaggacgccgacgtacgggccaccgaagtacggatggcgccc
gggggacagcccgccttcacactccacacacccaccgggtgcagtgatgtgaccttgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgtcctg
ggcatgtccgtatcggagatcgccaccgcgctctccggggcgggcaccctgtcccggtgg
cggatggaggtcaccgagcgggcggacggcgtgacgatcgtcaacgacgcctacaacgcg
aatcccgagtccatgcgggccgcactgcgcgcacttgccgcgatgggcggctccgcgagg
gccaacgggggtcgtacgtgggcggtgctcggccccatggccgagctcggtgacgcatcg
ttggccgagcacgacgcggtgggacggcttgccgtccggctcaacgtgagcaagctcgtc
gcagtcgggggcagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtggtcgtgtccgacgcgcaagcggcggtcgacctgttgcgcagtgaa
ctgcgcccgggtgacgtcgtgctggtgaaggcttcgaggtcgatcggtctggagcgggtc
gcgcttgcgttgctggagcgcgagggcgaggtcgccgaccgatga
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