Streptomyces xanthophaeus: KPP03845_105296
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Entry
KPP03845_105296 CDS
T08962
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sxt
Streptomyces xanthophaeus
Pathway
sxt00290
Valine, leucine and isoleucine biosynthesis
sxt00660
C5-Branched dibasic acid metabolism
sxt01100
Metabolic pathways
sxt01110
Biosynthesis of secondary metabolites
sxt01210
2-Oxocarboxylic acid metabolism
sxt01230
Biosynthesis of amino acids
Module
sxt_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sxt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
KPP03845_105296 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPP03845_105296 (leuC)
Enzymes [BR:
sxt01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
KPP03845_105296 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
KPP03845_105296 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
AcnX
Motif
Other DBs
NCBI-ProteinID:
WCD88881
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Position
5744933..5746357
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFEGLRQAGRKVRRLDLTIAT
EDHNTPTIDIDKPIADPVSRAQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVTGALAEGVTA
KDLILAIIARIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDRTTF
DYLQGRDHAPEGADWDAAVAYWQTLRTDDDAVFDAEVVIDGTTLSPFVTWGTNPGQGAPL
SANVPDPASYEDASERHAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAVAG
IIEGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSEAPATAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgaaggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgagggtctgcgccaggccggccgcaaggtccgacgcctcgacctcaccatcgcgacc
gaggaccacaacacccccaccatcgacatcgacaagccgatcgcggacccggtctcccgg
gcccagctggagacgctgcgcaagaactgcgccgagttcggtgtgcgcctgcattcgctg
ggtgacgtcgagcagggcgtcgtccacgtcgtgggaccgcagctgggtctgacccagccg
ggcaccaccgtggtctgcggcgactcgcacacctccacgcacggcgccttcggcgcgctg
gccttcggcatcggcaccagccaggtcgagcacgtgctggccacccagacgctgccgctg
gcccgtccgaagaccatggcgatcaccgtcaccggcgcgctggccgagggcgtcaccgcc
aaggacctgatcctggccatcatcgccaggatcggcaccggcggcggccagggctacgtc
ctggagtaccgcggcgaggccatcgagaagctgtcgatggaagcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgggcgggcatgatcgcccccgaccggaccaccttc
gactacctccagggccgcgaccacgcccccgagggcgcggactgggacgctgcggtcgcc
tactggcagaccctgcgcaccgacgacgacgcggtcttcgacgccgaggtcgtcatcgac
ggcaccacgctgtccccgttcgtcacctggggcaccaacccgggccagggcgcgccgctg
tcggccaacgtccccgacccggcttcgtacgaagacgcttcggagcgccacgccgccgaa
aaggccctggagtacatggggttgaccgccggacagccgctgcgtgacatcaaggtcgac
accgtcttcgtaggttcgtgcaccaacggccgcatcgaggacctgcgcgccgtcgccggg
atcatcgagggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctcggtc
cgggtggccctgcaggccgtggaagagggcctggacaaggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccaactggcgccc
ggtgagcgttccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcgga
cggacccacctggtctccccgcaggtggccgccgccaccgcggtgctgggccatctggcc
tcgcccgccgacctgtccgaagcccccgcgaccgccggagtctga
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