Streptomyces yangpuensis: NRK68_11395
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Entry
NRK68_11395 CDS
T08585
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
syan
Streptomyces yangpuensis
Pathway
syan00290
Valine, leucine and isoleucine biosynthesis
syan00620
Pyruvate metabolism
syan01100
Metabolic pathways
syan01110
Biosynthesis of secondary metabolites
syan01210
2-Oxocarboxylic acid metabolism
syan01230
Biosynthesis of amino acids
Module
syan_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
syan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NRK68_11395 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NRK68_11395 (leuA)
Enzymes [BR:
syan01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NRK68_11395 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
UUY47771
LinkDB
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Position
complement(2471344..2473107)
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AA seq
587 aa
AA seq
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MSQQPFVGRPTPITNATHTQKPSGMPIHKYGAYEQVDIPDRTWPDARVTKAPRWLSTDLR
DGNQSLIDPMTPARKREMFDLLVRMGYKEIEVGFPSSGETDFAFVRSIIEEGAIPDDVTI
SVLTQAREDLIERTVESLVGARRATVHLYNATAPTFRRVVFRGSKEQIKQIAVDGTRLVM
EYAEKLLGPETTFGYQYSPEIFTDTELDFALEVCEAVCDVWQPSEGREIILNLPATVERS
TPSTHADRFEWMARNLTRREHICISVHPHNDRGTAVAAAELALMAGADRIEGCLFGQGER
TGNVDLITLGMNLFSQGIDPQIDFSQIDEIRRTSEYCNQMPVHPRHPYAGDLVYTAFSGS
HQDAIKKGFDAMEADAAAQGKTVDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIA
YVLKNDHKLDLPRRMQIEFSKIIQAKTDAEGGEVTPKAIWDIFSDEYLPNPENPWGRIQL
RSGSTATDKDGTDTLTVEAVVDGVETVLNGTGNGPISAFFDALAGIGVDARLLDYTEHTM
SEGASAVAASYIECAIDGRVLWGIGIDANTTRASLKAVISAVNRAGR
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcagccttttgtcggtcgccccacgcccatcacgaacgcgacccacacccag
aagccctccgggatgccgatccacaagtacggcgcgtacgaacaggtggacatcccggac
cgcacctggcccgatgcccgcgtcaccaaggccccccgctggctgtccaccgacctgcgg
gacggcaaccagtcgctgatcgaccccatgacccccgcccgcaagcgcgagatgttcgac
ctgctggtgcgcatgggctacaaggagatcgaggtcggcttcccgtcctccggcgagacc
gacttcgccttcgtgcgctccatcatcgaagagggcgcgatcccggacgacgtcaccatc
tccgtactgacccaggcccgcgaggacctgatcgagcggaccgtggagtccctggtcggc
gccaggcgcgccaccgttcacctgtacaacgcgaccgcgccgaccttccgccgggtcgtc
ttccgcggctccaaggagcagatcaagcagatcgcggtcgacggcacccgtctggtgatg
gagtacgccgagaagctgctgggccccgagaccaccttcggctaccagtacagcccggag
atcttcaccgacaccgagctggacttcgccctggaggtctgcgaggccgtctgtgacgtc
tggcagccgtccgagggccgcgagatcatcctgaacctgcccgccaccgtggagcgttcg
acgccgtccacgcacgcggaccgcttcgagtggatggcccgcaacctgacccgccgcgag
cacatctgcatctccgtgcacccgcacaacgaccggggcaccgccgtcgcggccgccgag
ctggccctgatggccggcgccgaccgcatcgagggctgcctgttcggacagggcgagcgc
accggcaacgtcgacctgatcacgctgggcatgaacctgttctcccagggcatcgacccg
cagatcgacttctcgcagatcgacgagatccgccgcaccagcgagtactgcaaccagatg
ccggtccacccgcgccacccctacgcgggcgacctggtctacaccgccttctccggctcc
caccaggacgccatcaagaagggcttcgacgccatggaggccgatgcggccgcccagggc
aagaccgtcgacgacatcgagtgggccgtgccgtacctgcccatcgaccccaaggacgtc
ggccgctcctacgaggcggtcatccgggtcaactcgcagtccggcaagggcggcatcgcg
tacgtcctgaagaacgaccacaagctggacctgccgcgccgcatgcagatcgagttctcg
aagatcatccaggccaagaccgacgccgagggcggcgaggtcacgccgaaggcgatctgg
gacatcttctccgacgagtacctgcccaacccggagaacccgtggggccgcatccagctg
cgctccggctcgacggccaccgacaaggacggcacggacacgctgaccgtcgaggcggtc
gtggacggcgtggagacggtcctgaacggcaccggcaacggtccgatctcggcgttcttc
gacgcgctggccggcatcggcgtcgacgcccgcctgctggactacaccgagcacaccatg
agcgagggcgcgtccgccgtggccgcctcctacatcgagtgcgcgatcgacggccgggtc
ctgtggggcatcggcatcgacgccaacaccacccgcgcctccctgaaggcggtcatctcc
gccgtcaaccgcgcgggccgctga
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