Streptomyces yangpuensis: NRK68_11770
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Entry
NRK68_11770 CDS
T08585
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
syan
Streptomyces yangpuensis
Pathway
syan00790
Folate biosynthesis
syan01100
Metabolic pathways
syan01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
syan00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NRK68_11770
Enzymes [BR:
syan01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NRK68_11770
6.3.2.17 tetrahydrofolate synthase
NRK68_11770
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UUY47837
LinkDB
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Position
complement(2564877..2566415)
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AA seq
512 aa
AA seq
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MSDQQPENPDRHDHDDLAGAFDEFDQIVAEESDRDPDLAVIEAGSRTLRAHAGPPQGDPV
PARPVDPEVAEALLEVERELSTRWGETKLEPSVSRIAALMDVLGEPQRAYPSIHVTGTNG
KTSTARMIEALLNAFELRTGRYTSPHVQSITERISLDGAPIEAERFVETYHDIKPYVEMV
DAAEEFRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGSVAVVTPISLDH
TDRLGSTPGEIAVEKGGIIKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGMEFGVVS
REVAVGGQQLTLRGVGGEYDGIFLPLYGAHMAHNAAVALAAVEAFFGVGGQHARVLDVDT
VRKAFASVTSPGRMEVVRRSPTVILDAAHNPAGAAVTAEAVTEAFGFSRLVGVVAASEDK
DVRGVLEAFEPIFAEVVVTQNSSHRSMGADDLAAVAVEVFGVDRVQVEPRLDDALEAAIT
LAEEEAEYGGAGVLVTGSVITVGEARLLLKRG
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgaccagcagcccgagaaccccgaccgacacgaccacgacgacctcgcaggcgcc
ttcgacgagttcgaccagatcgtggcggaagagtccgaccgcgatcccgacctggcggtg
atcgaggccggcagccgcaccctgcgcgcccacgccggaccgccccagggggacccggtg
cccgcccggcccgtcgaccccgaggtcgccgaggcgctgctggaggtggagcgagagctc
tcgacccgctggggcgagaccaagctggagccctcggtgtcgcggatcgcggcgctcatg
gacgtactgggcgagccgcagcgcgcgtacccctcgatccacgtcaccgggaccaatggc
aagaccagcacggcccgcatgatcgaggccctgctgaacgccttcgagctgcgcaccggc
cgctacacgagcccgcacgtgcagtcgatcaccgagcggatcagcctcgacggggcgccg
atcgaggccgagcgcttcgtggagacgtaccacgacatcaagccgtacgtggagatggtc
gacgccgccgaggagttccggctgtccttcttcgaggtgctcaccgggatggcctacgcg
gccttcgcggacgccccggtggacgtggccgtggtcgaggtcggcatgggcggcagctgg
gacgcgaccaacgtcatcgacggctccgtcgccgtggtcaccccgatcagcctggaccac
accgaccggctcggctccacgcccggtgagatcgccgtggagaagggcggcatcatcaag
caggacgccaccgtgatcctggcgcagcagccggtcgacgcggcccaggtgctgctgaag
aaggccgtcgaggtcgacgcgacggtggcccgcgagggcatggagttcggcgttgtctcg
cgcgaggtcgcggtcggcgggcagcagctgacgctgcgcggcgtgggcggcgagtacgac
ggtatcttcctgccgctgtacggcgcgcacatggcgcacaacgcggcggtggcgctcgcc
gcggtcgaggccttcttcggggtcggcgggcaacacgcccgggtgctggacgtggacacc
gtccggaaggccttcgcgtcggtgacctcgccgggccgcatggaggtcgtgcggcgcagc
ccgacggtgatcctggacgcggcgcacaacccggcgggcgcggcggtcaccgcggaggcg
gtcaccgaggcgttcggcttcagccggctcgtcggcgtggtggcggcgagcgaggacaag
gacgtgcgcggggtgctggaggccttcgagcccatcttcgcggaggtcgtggtcacgcag
aactccagccaccggtcgatgggcgccgacgatctggcggccgtcgccgtcgaggtcttc
ggcgtggaccgggtgcaggtggagccgcggctggacgacgccctggaggcggcgatcacc
ctggccgaggaagaggccgagtacggaggggccggggtcctggtgaccggttccgtgatc
acggtgggcgaggcccgcctgctgctgaagaggggctga
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