Streptomyces yangpuensis: NRK68_19140
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Entry
NRK68_19140 CDS
T08585
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
syan
Streptomyces yangpuensis
Pathway
syan00860
Porphyrin metabolism
syan01100
Metabolic pathways
syan01110
Biosynthesis of secondary metabolites
syan01120
Microbial metabolism in diverse environments
syan01240
Biosynthesis of cofactors
Module
syan_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
syan_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
syan00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
NRK68_19140
Enzymes [BR:
syan01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
NRK68_19140
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
NRK68_19140
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UUY49134
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Position
4185544..4187211
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AA seq
555 aa
AA seq
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MNPSSPTTSAFPAVAAHGRVTFLGAGPGDPGLLTLRAVEALAAADVLIAEPEVLEVVRTH
ARAGVDTPQLTVADELSAAAGVPVIRDAANLVMEAARSGRRVVRAVTGDPGLDGNAADEM
LACATAGIPFEVVPGVATAVGVPAYAGVPLRDKQGADVRFVDAKTASARCWSEAGTSDGI
LVVSATLETASAAAAELVSAGRKPDTPLTVTVSGTTTRQRTWSATLGTIAQVFKQGKVLP
SPEGSRPVICVVGEHGAAARREDLSWFESKPLFGWRVLVPRTKEQAASLSDQLRSYGAVP
HEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGI
KVAAVGEQTAASLVEFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATE
TLVAGLIELGWEVDDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGK
PHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVSKLAEALAEYGAARREAAKAAGETVF
RPSERRPGARRRRTT
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
ttgaacccctcaagtccgaccacctccgccttcccggccgtcgccgcccacggacgcgtc
accttcctcggcgcaggcccgggcgacccgggtctgctgacgctgcgcgccgtcgaggcg
ctcgccgccgcggacgtactgatcgcggagcccgaggtgctcgaggtcgtacggacgcat
gcgcgcgcgggtgtcgacacgccgcagctgacggtagctgacgagttgtcagcagccgcc
ggggtcccggtgatccgggatgcggccaatcttgtcatggaggccgcacgctccggcagg
cgggtcgtgcgtgccgtcacgggcgaccccggactcgacggcaacgccgccgacgagatg
ctcgcgtgcgcgaccgcagggatccccttcgaggtcgtgcccggcgtcgcgaccgccgtc
ggcgtgcccgcgtacgccggtgtcccgctgcgcgacaagcagggcgcggacgtgcggttc
gtcgacgcgaagaccgcgtcggcgcgctgctggagcgaggccgggacgagcgacgggatc
ctcgtcgtctccgcgacgctggagaccgcctcggccgccgccgccgagctggtgagcgcc
gggcgcaagcccgacaccccgctgacggtgacggtctccggtacgaccacgcgccagcgg
acctggtctgcgaccctgggcacgatcgcccaggtgttcaagcagggcaaggtcctgccc
tcgcccgagggctcccgccccgtcatatgcgtggtcggcgagcacggcgccgccgcgcgc
cgcgaggacctgtcctggttcgagtcgaagccgctgttcggctggcgggtcctcgtaccg
cggacgaaggagcaggccgcttcgctctccgaccagctgcgttcctacggcgcggtgccg
cacgaggtgccgacgatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgcg
gtcaagggcctggtgacgggccgctacgagtggatcgccttcacctcggtcaacgccgtc
aaggccgtccgcgagaagttcgaggagtacgggctcgacgcgcgcgccttcgcgggcatc
aaggtcgccgcggtgggcgagcagaccgcggcctcgctggtggagttcggcgtgaagccg
gacctcgtgccgagcggcgagcagtccgcggccgggctgctggaggactggccgccgtac
gacccggtcttcgacccgatcgaccgcgtcttcctgccgcgcgccgacatcgcgacggag
acgctggtcgccgggctgatcgagctcgggtgggaggtcgacgacgtcaccgcctaccgg
accgtgcgcgcgtcgccgccgccggcggacacgcgcgaggcgatcaagggcggcggcttc
gacgccgttctcttcacgtcgtcctcgaccgtccgcaacctggtcggcatcgcgggcaag
ccgcacaacgtgacggtcatcgcctgtatcgggccggcgacggccaagaccgccgaggaa
cacggcctgcgggtcgacgtcctgtctccggagccgtcggtgtcgaagctggcggaggcc
ctcgccgagtacggcgcggcgcgccgcgaggcggccaaggcggccggcgagacggtgttc
cggccgagcgaacgccgcccgggcgcacgtcgtcgccgtacgacgtga
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