Streptomyces yangpuensis: NRK68_24410
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Entry
NRK68_24410 CDS
T08585
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
syan
Streptomyces yangpuensis
Pathway
syan00290
Valine, leucine and isoleucine biosynthesis
syan00660
C5-Branched dibasic acid metabolism
syan01100
Metabolic pathways
syan01110
Biosynthesis of secondary metabolites
syan01210
2-Oxocarboxylic acid metabolism
syan01230
Biosynthesis of amino acids
Module
syan_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
syan00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NRK68_24410 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NRK68_24410 (leuC)
Enzymes [BR:
syan01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NRK68_24410 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NRK68_24410 (leuC)
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GFIT
Motif
Pfam:
Aconitase
DUF4946
YopE_N
AcnX
Motif
Other DBs
NCBI-ProteinID:
UUY50091
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Position
5299756..5301180
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRKVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRANCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVTGALAEGVTA
KDLILAIIAKIGTGGGQGYILEYRGEAIEQLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLQGRDHAPVGEDWDAAVAYWKTLRTDEDAVFDAEVVIDGAALSPFVTWGTNPGQGAPL
SAQVPDPASYEDASERLAAEKALEYMGLTAGQPLRDIKVDTVFVGSCTNGRIEDLRAVAG
IIEGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSAADATAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgaaggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctgcgccaggccggccgcaaggtccgacgcctcgacctcaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagccgatcgcggacccggtctcccgg
gcccagctggagacgctgcgcgcgaactgcgccgagttcggtgtccgcctgcactcgctg
ggcgacgtggagcagggtgtggtccacgtcgtgggaccgcagctgggactgacccagccc
ggcaccaccgtggtctgcggtgactcgcacacctcgacgcacggcgccttcggcgcgctc
gccttcggcatcggcacgagccaggtcgagcacgtactggccacccagacgctgccgctg
gcccgcccgaagacgatggcgatcaccgtcaccggcgcgctggccgaaggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaagatcggcaccggcggcggccagggctacatc
ctggagtaccgcggcgaggccatcgagcagctctcgatggaagcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgatcagaccaccttc
gactacctgcagggccgcgaccacgcccccgtgggcgaggactgggacgcggccgtcgcg
tactggaagaccctgcgcacggacgaggacgcggtcttcgacgcggaggtcgtcatcgac
ggcgccgcgctctccccgttcgtcacctggggcaccaacccgggccagggcgcgcccctg
tcggcccaggtccccgacccggcttcgtacgaggacgcttcggagcgcctcgcggccgaa
aaggccctggagtacatggggttgaccgccgggcagccgctgcgcgacatcaaggtcgac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgtcgccggg
atcatcgagggccgcaaagtcgccgacggcgtacggatgctggtcgtaccgggctcggtc
cgcgtcgccctccaggccgtggaagagggcctggacaaggtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgttcgatgtgcctgggcatgaacccggaccaactggcgccc
ggtgaacgctccgcgtccacctccaaccgcaacttcgagggccggcaggggaagggcggg
cgtacgcacctggtgtccccgcaggtggccgccgccaccgccgtgctgggccatctggcc
tcgcccgccgacctgtccgccgccgacgcgaccgccggagtctga
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