Thermodesulfobium acidiphilum: TDSAC_0628
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Entry
TDSAC_0628 CDS
T05396
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alan ine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
taci
Thermodesulfobium acidiphilum
Pathway
taci00300
Lysine biosynthesis
taci00550
Peptidoglycan biosynthesis
taci01100
Metabolic pathways
taci01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
taci00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TDSAC_0628
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TDSAC_0628
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TDSAC_0628
Enzymes [BR:
taci01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TDSAC_0628
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AWB10001
UniProt:
A0A2R4VZM2
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Position
592556..593989
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AA seq
477 aa
AA seq
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MSADRDVNKLNSIQNFDPGGSISLSFITSLTNCEIERVGPMEFERISIDSRDIKGKELFI
AIKGKNFDGHNFIRNALEQGAFGIISELSLAGIASSLGDIVFENDFSFMRVPNTILAMHD
IARGFRQRIERVIGITGSVGKTTTKEILKTLLKRYQTVSTFGNFNNEIGLPLSLFRAKKN
DKFGIFEMAMRSRGEISQLCSIALPDIGIITRIAESHIGLLGSMENIARAKGEILDFVNS
AFLNFNCTYSRKIFGEMLKNKREKPKEIFWFGKVSDIYIKSYEISIYGSRLEFSGRFGNF
ALNAPNIFLPQFEPLLASVAVARFLGLDWNEINDNLQSYVPLQGRFLIKKLRDQIVIDDS
YNATCTSFIKGLETIKSLKFGSRRKIFIFGDILEAGDESKDLHRKVIKKIEELDPYLVYF
VGTEFVKSIDHNSKIRFKNMDIDCVKEDLAKILSKDEIVYIKGSNSTKTWKILELWN
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
ttgagtgctgatagggatgttaataaattgaatagtatccaaaattttgatcctggtggt
tctatttcgttaagctttattacatctttaactaattgtgaaattgaaagagttggccct
atggaatttgaaagaatttcaatagattcaagagatatcaaagggaaagaactttttatt
gccattaaaggtaaaaattttgatggacacaattttattaggaatgccttagaacaaggt
gcttttgggataatttctgaattgagtttggcaggaattgccagttctttgggggatata
gtttttgagaatgacttttcatttatgagagttccaaataccattcttgcaatgcatgat
attgcaagaggatttagacaaaggattgaaagggttataggcattactggaagtgtaggt
aaaacaactaccaaagaaattttgaaaacgcttctcaaaagatatcagacagtatcaact
tttggtaatttcaataatgaaattggtttgccattaagtctttttagagctaaaaaaaat
gataagtttggaatttttgaaatggctatgcgctcaagaggggaaatttctcagctttgt
tcaatagccttgcctgatattggtataattacaagaattgcagaatctcatattggactc
cttggttcgatggaaaacatagcaagagcaaagggagaaattttagattttgtaaatagt
gctttcttaaatttcaattgcacatatagcagaaaaatttttggcgagatgcttaagaat
aagagggaaaagcctaaagagattttttggtttggaaaagtatcagatatttacattaaa
tcatatgaaatttccatatatggttcaaggcttgaattttccggaaggtttgggaatttt
gctttaaatgcaccaaatatttttttgcctcaatttgagccgcttttggcgtcagtagca
gttgcaagatttttaggccttgactggaacgaaataaatgataatttacaaagttatgtg
cctttacagggcagatttttaattaaaaaactaagagatcaaattgttattgatgattct
tataatgcaacatgtacttcttttataaagggattggagacaattaagagtttaaaattt
ggcagcagaagaaagatatttatatttggagatatacttgaggctggagatgagtctaag
gatttacacaggaaggttataaaaaaaattgaggaattagatccatatttggtatatttt
gttgggacagagtttgtaaaatcaatagatcataattctaagataaggtttaaaaatatg
gatattgactgtgttaaagaggatttagctaaaatcttatccaaagacgaaattgtttat
attaaaggttcgaactctacaaaaacatggaaaattcttgagttgtggaattaa
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