Tachyglossus aculeatus (Australian echidna): 119919742
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Entry
119919742 CDS
T10703
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu01521
EGFR tyrosine kinase inhibitor resistance
tacu01522
Endocrine resistance
tacu04010
MAPK signaling pathway
tacu04012
ErbB signaling pathway
tacu04014
Ras signaling pathway
tacu04062
Chemokine signaling pathway
tacu04068
FoxO signaling pathway
tacu04072
Phospholipase D signaling pathway
tacu04150
mTOR signaling pathway
tacu04151
PI3K-Akt signaling pathway
tacu04510
Focal adhesion
tacu04540
Gap junction
tacu04630
JAK-STAT signaling pathway
tacu04650
Natural killer cell mediated cytotoxicity
tacu04660
T cell receptor signaling pathway
tacu04662
B cell receptor signaling pathway
tacu04664
Fc epsilon RI signaling pathway
tacu04714
Thermogenesis
tacu04722
Neurotrophin signaling pathway
tacu04810
Regulation of actin cytoskeleton
tacu04910
Insulin signaling pathway
tacu04912
GnRH signaling pathway
tacu04915
Estrogen signaling pathway
tacu04917
Prolactin signaling pathway
tacu04926
Relaxin signaling pathway
tacu04935
Growth hormone synthesis, secretion and action
tacu05034
Alcoholism
tacu05160
Hepatitis C
tacu05161
Hepatitis B
tacu05163
Human cytomegalovirus infection
tacu05165
Human papillomavirus infection
tacu05200
Pathways in cancer
tacu05205
Proteoglycans in cancer
tacu05206
MicroRNAs in cancer
tacu05207
Chemical carcinogenesis - receptor activation
tacu05208
Chemical carcinogenesis - reactive oxygen species
tacu05210
Colorectal cancer
tacu05211
Renal cell carcinoma
tacu05213
Endometrial cancer
tacu05214
Glioma
tacu05215
Prostate cancer
tacu05220
Chronic myeloid leukemia
tacu05221
Acute myeloid leukemia
tacu05223
Non-small cell lung cancer
tacu05224
Breast cancer
tacu05225
Hepatocellular carcinoma
tacu05226
Gastric cancer
tacu05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119919742 (SOS1)
04012 ErbB signaling pathway
119919742 (SOS1)
04014 Ras signaling pathway
119919742 (SOS1)
04630 JAK-STAT signaling pathway
119919742 (SOS1)
04068 FoxO signaling pathway
119919742 (SOS1)
04072 Phospholipase D signaling pathway
119919742 (SOS1)
04151 PI3K-Akt signaling pathway
119919742 (SOS1)
04150 mTOR signaling pathway
119919742 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
119919742 (SOS1)
04540 Gap junction
119919742 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
119919742 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
119919742 (SOS1)
04660 T cell receptor signaling pathway
119919742 (SOS1)
04662 B cell receptor signaling pathway
119919742 (SOS1)
04664 Fc epsilon RI signaling pathway
119919742 (SOS1)
04062 Chemokine signaling pathway
119919742 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
119919742 (SOS1)
04912 GnRH signaling pathway
119919742 (SOS1)
04915 Estrogen signaling pathway
119919742 (SOS1)
04917 Prolactin signaling pathway
119919742 (SOS1)
04926 Relaxin signaling pathway
119919742 (SOS1)
04935 Growth hormone synthesis, secretion and action
119919742 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
119919742 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
119919742 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119919742 (SOS1)
05206 MicroRNAs in cancer
119919742 (SOS1)
05205 Proteoglycans in cancer
119919742 (SOS1)
05207 Chemical carcinogenesis - receptor activation
119919742 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
119919742 (SOS1)
05231 Choline metabolism in cancer
119919742 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
119919742 (SOS1)
05225 Hepatocellular carcinoma
119919742 (SOS1)
05226 Gastric cancer
119919742 (SOS1)
05214 Glioma
119919742 (SOS1)
05221 Acute myeloid leukemia
119919742 (SOS1)
05220 Chronic myeloid leukemia
119919742 (SOS1)
05211 Renal cell carcinoma
119919742 (SOS1)
05215 Prostate cancer
119919742 (SOS1)
05213 Endometrial cancer
119919742 (SOS1)
05224 Breast cancer
119919742 (SOS1)
05223 Non-small cell lung cancer
119919742 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
119919742 (SOS1)
05160 Hepatitis C
119919742 (SOS1)
05163 Human cytomegalovirus infection
119919742 (SOS1)
05165 Human papillomavirus infection
119919742 (SOS1)
09165 Substance dependence
05034 Alcoholism
119919742 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119919742 (SOS1)
01522 Endocrine resistance
119919742 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
Motif
Other DBs
NCBI-GeneID:
119919742
NCBI-ProteinID:
XP_038596372
LinkDB
All DBs
Position
1:complement(139940009..140221799)
Genome browser
AA seq
1335 aa
AA seq
DB search
MQAPQLQYDFFCDDNAPKWRGLLVPALKKVQMQVHPTLLSTEDALQYVEELILQLLSMLC
QAQPRSVLDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHFEITKQDIKVAMCADKVLMDMFHQDV
EDISVLSLTDEEPSSSGEQTYYDLVKAFMAEVRQYIRELNLIIKVFREPFASNSKLFSAH
DVENIFSRIADIHELSVKLLGHIEDTVEMTDESSPHPLVGSCFEDLAEELAFDPYESYAQ
DILRTGFHGHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDEEDKECLKQAITALLNLQSSMERICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDATMLQEEKEEQMRLPSSELYRFAEPDSEENIVFEENMQPKSGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIGRFEIPEPQPTEADR
RAMENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRLEEFIGT
VRGKAMKKWVESITKIIQRKKQAQANGPSHNITFESSPPSIEWHISRPGHTETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEFLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIRRFFENLNPVGNSMEKEFPDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASAASSTTDACSVFDSDHSSPFHSSSDTIFIQVSLPHGPRSASVSSISF
TKSTDETPVPPPVPPRRRPESAPAESSPSKMMSKHLDSPPAIPPRQPTSKGYSPRYSVPD
ARTPLSDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGRKSELGNAFFPNSPAPFTPP
PPQTPSPHGTRRHPPSPPLIPQDVDLHSVAGPPVPPRQSTSQHIPKLPPKTYKREPTHPS
MHRDGPPLLENAHSS
NT seq
4008 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgccgcagctgcagtacgacttcttctgcgacgacaacgcccccaagtggcgg
gggctgctcgtccccgcgctcaagaaggttcagatgcaagtccacccgacacttttgtct
accgaggatgccctccagtatgttgaagagttaattctgcagttgttaagtatgctgtgc
caagcccagcctcgaagtgttttagatgtagaggagcgtgttcaaaaaagttttcctcat
ccaatcgataagtgggcgatagcggatgcccagtctgctattgaaaagaggaagcgaaga
aacccattatctctcccagtagaaaaaattcaccctttattaaaggaagtcctaggttat
aaaattgaccaccaagtttctgtttacatagtagcagtattagaatatatttctgcagat
attttaaagctggtcgggaattacgtgcggaatataaggcattttgaaattacaaagcaa
gacattaaagtggccatgtgtgctgataaggttttgatggatatgttccaccaagatgta
gaagacataagtgtattatctttgacagacgaagagccttcttcctcaggggagcaaact
tactatgacctagtcaaagcatttatggccgaggtccgacagtacataagggaactcaat
ctcatcattaaggttttcagagagccatttgcttccaattcaaagttattttcagctcac
gatgtagaaaacatatttagtcgaatagcggatattcacgaactgagcgtgaagttattg
ggccatatcgaagacacagtggaaatgacggatgaaagcagcccccacccgttagtaggt
agttgctttgaagacttagcggaggaactggcattcgacccatatgaatcatatgctcaa
gatattttacgaactggtttccacggtcattttcttagtcaattatccaagcccggggca
gcactctatctgcagtcaataggagaaggtttcaaggaagctgttcagtatgttttgccc
agattactcctggcccccgtctaccactgtctgcattactttgaacttctaaagcaattg
gaagaaaagagtgaagatgaagaagacaaggaatgtttgaaacaagctataacagccctt
cttaaccttcaaagtagtatggaaagaatatgttccaagagtcttgcgaaaaggaggcta
agtgaatctgcatgtcgattttatagtcagcagatgaaggggaagcagctagccattaag
aaaatgaacgagatccagaagaacatcgatggctgggagggaaaagacattggacagtgt
tgcaacgaattcatcatggaaggcaccctcacccgtgtaggggccaaacacgagcggcac
atatttctcttcgacggcttgatgatctgctgtaaatccaaccacggccaaccgaggctt
cccggggccagcaacgcggagtaccgcctcaaagagaagttcttcatgcggaaggtccaa
attaacgacaaggacgacacaaacgaatacaagcacgccttcgagatcatcctgaaggac
gagaacagcgtgatattctcggccaagtcggcggaggagaagaacaactggatggccgcg
ttgatatctttacagtaccggagcaccttggagaggatgctggacgcgaccatgctgcag
gaggagaaggaagagcagatgaggctccccagttccgagctctataggtttgcggagcca
gactccgaggagaacatcgtgtttgaggagaacatgcagcccaaatcgggaatccccatc
attaaagcggggactgtaattaagctcatagagcgactgacataccacatgtacgcagat
cccaattttgttcggacatttctcaccacatatagatccttctgcaaacctcaagagctt
ctgagtcttctcataggaaggttcgaaatcccagagcctcagccaaccgaagcggatcgg
agagcgatggaaaatggagatcagccccttagcgcagaactcaaaagatttaggaaagag
tacatccagcccgtgcagctgcgggtattaaatgtatgtcggcattgggtagagcaccac
ttctatgattttgaaagagatgcggatcttcttcagcggttggaagaatttattggaaca
gtccgaggtaaagcgatgaagaaatgggtggaatccatcacaaagataatccagcggaag
aaacaggcccaagccaacggaccgagccacaacattacatttgaaagttcacctccctcc
attgagtggcacataagcagaccagggcatacagagacttttgacttgctcacactgcac
ccgatagaaattgcccgacagctcactttacttgaatctgatctttaccgagctgttcag
ccatcagagttagttggaagtgtgtggacaaaggaagataaagaaattaattctcctaac
ctgctaaaaatgattaggcacaccactaatctcaccttatggtttgaaaagtgtattgta
gaaacagaaaatctagaggagagagtagctgtcgtgagtcgaataattgagatcttacaa
gtatttcaagaattgaacaattttaatggtgtgcttgaagttgtaagtgccatgaactca
tcacctgtgtatagactagaccacacatttgagcaaataccgagtcgccaaaagaaaatt
ttagaagaagctcacgaattgagcgaagatcactataaaaaatatttggcaaaactcagg
tctattaatccaccatgcgtgcctttctttggaatttatttgactaatatcttgaaaaca
gaagaaggcaatcccgagtttcttaaaaggcatgggaaagaactgatcaactttagcaaa
aggaggaaagtggcagaaataacgggagagatccagcagtaccaaaatcaaccatattgc
ctacgagtagagtctgacatcagaaggttctttgaaaatttgaatccagtgggaaatagc
atggagaaggaattcccagattaccttttcaacaagtccctggaaatagagccacgtaat
cccaagcctctaccaagatttcccaaaaaatacagctatcccctcaagtcgcctggcgtc
cgtccatccaacccaagacccggtaccatgagacacccgaccccgctgcagcaggagccg
aggaaaatcagctacagtcggatccccgaaagcgaaaccgagagcacggcgtccgcaccc
aattctccgcgaacccctttaacgccgccccctgcctctgctgcttccagcaccacagac
gcttgcagcgtgttcgattccgaccactcgagtcccttccactcaagcagcgataccatc
tttatccaggtttccctgccccatggcccacgatctgcttcggtatcatccatcagcttt
accaagagcaccgatgagactcccgtccctcccccagtccctccaaggaggcggccagag
tccgccccagccgaatcgtctccatccaagatgatgtctaagcatctggacagccctccg
gcgattcctccccggcaacccacgtcgaaaggctactccccacggtactcggtgccggac
gcccggacccccctgtcggaccctcccgaaagccctcctttactgccgccccgcgaaccc
gtgaggacccccgacgtcttctccagctcaccgctgcacctgcagcctccccctctgggc
cgcaaaagcgaactcggcaacgccttcttccccaacagccccgctcccttcacccccccg
cccccccagaccccttcccctcacgggacccgccggcacccgccctcgcccccattgatc
ccccaagacgtggacctccactccgtcgccgggccgcccgtacctccgcgacaaagcact
tctcaacacatccccaagcttcctcccaaaacgtacaagagggagcccactcacccgtcc
atgcaccgggacgggcccccgctgttggagaacgcccactcctcctga
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integrated database retrieval system
