Tachyglossus aculeatus (Australian echidna): 119927393
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Entry
119927393 CDS
T10703
Symbol
SETX
Name
(RefSeq) probable helicase senataxin
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
119927393 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
tacu03021
]
119927393 (SETX)
Enzymes [BR:
tacu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
119927393 (SETX)
5.6.2.5 RNA 5'-3' helicase
119927393 (SETX)
Transcription machinery [BR:
tacu03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
119927393 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
SEN1_N
AAA_19
AAA_30
UvrD-helicase
AAA_22
AAA_16
SLFN-g3_helicase
ResIII
Motif
Other DBs
NCBI-GeneID:
119927393
NCBI-ProteinID:
XP_038601965
LinkDB
All DBs
Position
4:112618622..112687931
Genome browser
AA seq
2746 aa
AA seq
DB search
MSTCCWCTPGGSSTTDVLREYASKNISCEFFIAANDDLCYCLECVAEYHKARDQLPFLHE
VLWELETSRLVGHFEKCIKEVGEDDELFIINDNRETHLSNISGSDFENNLRVPLLEILKY
PYLLLNERVSELFVEGLCRMEQANCSFQVFDKHPGIYLLLVHPNEMIRRWAILSARNLGK
VDRDDYYDLQEVLTCLFKVIELGLFESPDIYTSSLLEMGKLILLPCHMYDTMNYKNYWLG
ICLLLTILEEQAMDSLFLGAGKQNDFMKSILHTMERQENDDSMNPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNKEIENIRTSSNRAKLEPESNFEEDMVTCSQIVYNY
NPGKSKKDSGWRSAICPDYCPNMYEEMETLTNLLQSDIGQDMRVHNSTFLWFIPFVQSIM
DLKDLGVAYIVEVIHHLYSEVKDVLNEKVALCDKVTEFFLLILVSVIELHRNKKCLHLLW
VSSQQWVEAVVKCAKLPATAFARFAEKSAGSCPRVTSTISGLSLNSQPSNSVQHACVLLI
RSILREGYQLGQQTICKQFLDKLNLLLRGNLSLGWQLNRQETQELQMCLKQIVRNINVRV
PKGVTSLEQNVVCKAQPKVSVKEESEITGERMRRDKSPTFSKGRRKAGAYLKQENPSSRR
ISACEEDRVGRGFGASEEDGGLSSESCLDHLKEPVAKRSRDPGISNGVALEAPKIAQGIN
IVKDFASKGAEKARFEGRTKVPGLWGIESRSNSSENVFRSNENTCSKNEDNRKNTKLKPN
IQKDDLCAKLFQVMKQCPRKTKMANQSEDAEANQRPSSIGSCCPKKEAESRRENTVTRKS
SLDDCVTPEDAETEGAGSRNDTLVIKEEPNDQINYLAYHKNYDCLQESDSKDEDKISHKV
IGQATLEKYLHRQESRTDSLSPSFTRKSNWKETNEFACSVPWNTIREVSAKSVIVSPSST
HATEDHDKETLIAYAKGLSLLSDSAPEDSPQLQNIKRKVKDAVKLAMNNQSDDSVSSVET
LKSQVIIISDSSSDEERALTVSEEIKTTVTDIKKGSSERCPSVSNVEDELEAKEGSTSPL
ESEECDSQMFEFETQEQVYSFWQDSEASDKNLETEQETRLIPTVAHSLEHLNDWGYETDY
ICDDIIEKVVEDMEKHLEPLAGSLSLEECEKIEVKPGSHRSKNPTAKGPKEPLPNFKNIG
QAKACSTAATVKGRSDSDVEASTSASTLSVTPSLSKISNESPGTVFPSKSVSSPYFTSKE
PVSQSHKKICVKENKGQNKTLNKTSSKETPSCRSTPAVVPPKKFRPCPEPTSTVERLGLK
KRPRKAFELSQRSLDSLAKLRNYGQTAGAVSSHKKQKAKLISPQALVIKNNKKLLACQDL
QFLRQMKSEPKKNLKGLPASRSRNFPRALSNPVLAPGARRQSSSGTRDGFKSKVELVSSS
DGRRQREDADTEAVQTGRISETVDGTTNPLTKQDSLDSKVRLIQASEALVSSSEDHSRGS
FSSGGCGFSGDLEDQVDLQAPLSFGPETKSSREAESKCNDDKEEDNLFLTQTDTVDMELC
SQVETFEDFQAFPENEPKEVKDNPQPGASDGIKCKHKDCTEAVVNLGESCSKHSVVKTSD
EHLFAKPAVPMSPLFKTAKPPTAKVFSSSSTSRNAAFSKDLEKSPKLPLPLKTKPNVMKP
PASKVTKPTPATAQGSVLKPDEEKNPRSVLQPYNKQAPSYFSRSAPPVQPGPKNPYLLVS
SFAAQQSYYSSFLSEILKWKCEMFKDIGQLGPPANLCKTILSPVPLSFQNYDDYFNIFFP
LMMLNTFETVAQEWLENQKKDNSYQLHLRSFYSGDVNSAKFMVYVKEKDMAKQLHPKEDD
LILLEVPGGISGFAAEKNEVIRHPVYHTAYVSQFTRSSARHTDRQVICNVAVQTKSNLAS
YINQPVKCTIISSLVTTQRKFRALLSLSRSPLAGTIINPHISDFCPRDSVKPAPEKTVAY
LKDFNEDQKKAIETAYSMVMLHPSLPRICLIHGPPGTGKSRTIIGLLHRILNETPKERPA
PNLNAKIKRNRVLVCAPSNAAIDELMKKIILEFKEKCQNKKSPLGNCGDINLVRLGPEKS
ISSEVLKFSLDSQVNYRMKKALPSRDQDLHKRKEALDHQLDQLSRQRAMDRCEKGEKSQN
LDEEIARLSAQREQLASKLKEVRGRPQEIQSNIILGSHIICCTLSTSGGFLLESAFRRQG
YEPFSCVIVDEAGQACELETLIPLIHRCNKLVLVGDPKQLPPTIISLKAQEFGFDQSMMA
RLCKNLENQVEQNLARKAPILQLTFQYRMHPDICLFPSNYIYGRSLKTSRATEEARCSLD
WPFLPYLVFDVEDGLERREHESYFNFQEIKLVIELIKMIKDKEKDITSRNIGVITPYKSQ
KKMIQCELDKEFEKIRLGEVDTVDGFQGRQKDCIIVTCVRANSTQDIGFLSSVQRLNVTI
TRAKYSLFILGHLKTLMENKDWSQLIQDAQRRGAIIRTCEANYRQDVRRILKPKLVSQQL
PLKAAEEKTRPQAVLSGEKPKDTAEGLENITSSPTIAPSLPSPQCGGPSNRAEPPPPDHQ
KKGAQAAPGKALITSPAQNQPRDPRLAWRRDFSAKERPPKEPTAYPRQELSGLGADPGQS
RILDHSVSKVAARTLSNPQPDGPSTQGSGQSTQKSRHQSWEGSRRETPSPRRGGQEKQAP
RRDKYSDLDRDYRLERGSHSKKDFRPGRVQDTQENRDSDAKRRKVS
NT seq
8241 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgctggtgtacgcctggtggttcttccaccacagatgtcctaagggaa
tatgcatccaagaacatatcctgtgaattcttcatagcggccaacgatgacttgtgttac
tgtctggagtgtgtggctgaataccacaaggcaagagatcagctgcccttcttgcatgag
gtcttgtgggaactggaaacttcccggcttgtggggcattttgaaaagtgcattaaagaa
gttggagaagatgatgaactgtttataataaatgacaatagggaaacacatctttctaat
atcagtggctcagactttgaaaacaatctgcgagttcctcttctggaaattctaaagtac
ccctatttgttgctaaatgagcgtgtcagtgagttatttgtcgaaggactgtgtaggatg
gagcaagctaactgttcctttcaagtctttgacaaacatccaggaatctatttgctcttg
gtacatcccaatgaaatgattcgacggtgggctatcctgagtgccagaaatctggggaag
gtagaccgtgatgattattatgatctacaagaagtgttaacttgtttatttaaagtaatt
gagttgggcctttttgaaagccctgatatatatacatcatctttgctcgaaatgggcaaa
cttattcttctgccatgtcacatgtatgacaccatgaactataagaactactggctgggc
atctgtttactgctaaccattcttgaggaacaagctatggattctctgttcctgggtgca
ggcaagcaaaatgattttatgaagtctatactacataccatggagagacaagaaaatgat
gatagtatgaatcccttctggccagcattacactgtttcatggtgattctggatcggctt
ggatcaaaagtgtggggtcaacttattgaccccattgaggcattccagaccattatcaac
aatgtgagctacaacaaagaaatcgaaaatatacgtaccagctctaacagggcaaaattg
gaacctgagtcaaattttgaggaagacatggtgacctgcagccagattgtgtacaattat
aatccagggaaatccaaaaaagactcaggatggaggtcggcaatctgtccagattactgt
ccaaatatgtatgaagaaatggagaccttgaccaacttacttcagtctgatattggtcag
gatatgcgtgttcacaatagcacatttctgtggttcatccctttcgttcagtccatcatg
gatcttaaggacttgggggtggcttacatagtggaggtcattcaccatctgtactcagaa
gtcaaagacgtcctgaatgagaaagtggcactgtgtgacaaagtcactgagtttttcctc
ttgatcttggtgtcggtgattgaactgcatcggaataaaaagtgcttgcatttgctgtgg
gttagctctcagcagtgggtggaggctgtggtgaagtgtgctaaacttcctgccacggcc
tttgcaaggtttgcagagaaaagtgctgggagttgccccagagtcacttcaaccatttca
ggactgtctttgaattcacagccatctaactccgtccagcatgcttgtgtactcctgatc
cgtagtattctcagggaaggttatcagcttggacagcaaactatttgcaaacagttcttg
gacaaactcaatttgctcctgcggggaaacttatcccttggttggcagttaaacaggcag
gagactcaagaattgcaaatgtgtttaaagcagattgttagaaatataaatgttcgcgtg
ccaaagggtgtcacttctctggaacagaatgttgtttgtaaagctcagcctaaggtatcc
gtaaaagaagaaagtgagattacaggagagaggatgagaagggacaaaagtccaacattt
tctaaagggcggcggaaagccggcgcgtatctgaagcaagaaaacccatcttccaggaga
atcagtgcttgtgaagaggatcgagtgggaaggggttttggagcatcagaggaagatggt
gggctctcatctgaatcctgcttagaccatcttaaggaacctgtggccaaaagatctcga
gatcctggaatttcaaatggtgtggcattggaggcaccaaagattgctcaagggataaat
atagttaaagactttgcctcaaaaggggcagaaaaagctagatttgaaggcagaactaaa
gtacctggattgtggggcatcgagtcaaggtctaattcttctgaaaatgtatttaggtca
aatgagaatacctgttcaaagaatgaggataacagaaaaaacaccaagctgaaacccaac
atccagaaggatgatttgtgtgcaaaactatttcaggtaatgaaacagtgtcccagaaaa
accaaaatggcaaatcagtctgaagatgctgaggcaaatcagaggccatcaagcattggg
agttgctgcccaaagaaagaagccgaaagccgaagagagaacacggtcactcggaaatca
agtttagacgactgtgttactccagaagatgctgaaactgaaggggcaggatccagaaat
gacaccttagtcattaaagaagaaccaaatgatcagataaactatttagcgtatcataaa
aattacgactgcttgcaagaaagtgatagcaaggatgaagataaaatttcacataaagta
attgggcaagcaacactggaaaaatatctacatagacaagaatcaagaactgacagtctt
tcaccttcttttacaagaaaaagtaattggaaagaaacaaatgagtttgcctgttctgtt
ccatggaacacgataagagaagtctctgctaaaagtgtcattgtcagcccctctagtacc
cacgccactgaagaccatgataaagagactctcattgcctatgccaagggtttgagcctt
ctttcggattcagcgccagaagattcgcctcagctgcagaatattaaacgaaaagtgaaa
gatgcggtgaaattggccatgaacaatcaaagtgatgactccgtttctagtgtggaaacc
ctcaagagtcaagtcatcataatttcagattcctcttctgatgaggaaagggcgctgact
gttagtgaagagataaaaactacagtaacagacattaagaaaggaagttcagaacgatgt
ccttcagtgtctaatgtagaggatgaactagaggcaaaagagggctcgacatcaccttta
gagtctgaggagtgcgattctcagatgtttgagttcgaaacccaagagcaggtgtattca
ttttggcaagactctgaagcttctgacaagaatttagaaaccgaacaagaaactcgattg
attcccactgtcgcacactcactggaacacttaaacgactggggttacgaaacggattac
atctgtgatgacataattgaaaaagtagtagaggatatggagaaacatttggagccgctc
gctggtagtctttctcttgaggaatgtgagaaaatcgaagtgaagcctggaagtcatcga
tctaaaaaccccacggctaaaggccccaaagaacctctgcctaacttcaaaaatataggc
caagccaaagcttgttctactgccgctactgttaaaggtcgttccgacagtgatgtggag
gccagcacttccgcgtctactctgtcagtgacgcccagtttgagtaaaatttcaaatgaa
agtccaggcacagtgtttccttcaaaatctgtgtctagcccctatttcaccagcaaggaa
ccagtttctcaaagccacaagaaaatatgcgtcaaagaaaacaaagggcaaaataaaacc
ttgaataaaacgtcttctaaagagactccttcttgccggtctactcctgcagtggttcca
cccaagaagtttcgcccctgtccagaaccgacgtcaacggtggaaaggcttggtctgaaa
aagaggccccgcaaagcatttgaattatcccagcggtctttagatagcctggccaagctg
cgcaactacggccaaaccgcaggagcagtcagtagtcataaaaagcaaaaggcaaaatta
atttctccccaggctcttgttatcaaaaataataaaaagctgttggcgtgccaggatctg
cagtttctcaggcaaatgaagtccgaacccaaaaaaaatctgaaagggcttccggccagt
cgaagcagaaattttccaagggccttgtcaaatccagtcctggcacctggagcacggagg
caatcatcatccggaactagagacggtttcaagtcaaaagttgagctagtctcaagcagt
gatggaagaaggcagagagaagatgcagatacggaagcggttcaaaccggccgtatctct
gaaactgttgatggtactactaaccctctgaccaagcaagactcgcttgactcaaaggtt
cgcttgattcaagcaagtgaagctcttgtttcttcttccgaagaccattcaaggggctcc
ttttcaagcggaggttgtggtttcagcggtgacctcgaagatcaagttgatcttcaggcc
ccactgagctttggacctgagacgaaatcttccagggaagcagaatccaaatgtaatgac
gataaagaggaggataatttattcttgacacaaacagacacggttgatatggagttatgc
tcacaggtggagacctttgaagatttccaagcgttccccgaaaatgagccgaaggaggtt
aaagacaacccccagcctggggcttcagacggcataaagtgtaaacacaaagactgtaca
gaggcagttgtgaacctaggagaaagctgttccaagcattctgtagtcaaaacctcagat
gaacatctttttgctaaaccagctgtgccaatgtcaccactgtttaaaacagctaaacct
cccactgctaaagttttcagttcaagcagtacttcccggaacgccgccttttccaaagat
ttagaaaagtctccaaagctcccattacccttgaaaactaaaccaaatgtgatgaagcca
ccggcctcaaaagtaacaaaaccaactcctgctactgcccagggatcagtgttgaagcct
gatgaagagaaaaatccccgcagtgttcttcaaccatacaacaagcaggcgcctagttat
ttcagcaggtcagcccctccagttcagcccggccccaaaaatccctatctgctagtcagt
tcttttgccgcccagcaaagttactacagctcatttcttagcgagattctgaagtggaag
tgtgaaatgttcaaagacatcggccagttgggccccccggcaaacctctgcaagaccatc
ttgagtcccgttcccctcagcttccaaaactacgatgactattttaatatctttttcccc
ctgatgatgctgaacaccttcgaaacagttgctcaagaatggttggaaaatcagaagaaa
gacaattcttaccagcttcatttacgaagcttctacagtggtgacgtcaattctgcaaaa
tttatggtttacgttaaggaaaaagacatggctaaacaactgcaccccaaggaggatgat
ctaatacttttggaagtacctggagggataagtggttttgctgcagaaaaaaatgaagtg
atacgtcacccagtgtatcacactgcttatgtttcccagtttacacgctcttcagccagg
catacggatcggcaagttatttgtaatgttgccgttcaaaccaaaagcaacttggcgagt
tacataaaccaaccagtgaaatgcaccattattagttctctggtgactacccagcgtaaa
ttccgagctttgctctcactgagtcgaagtccgttggccggaacaattataaatccacac
atctcagacttctgcccccgggattcagtgaaaccagctcctgagaagacagttgcttac
ctgaaagatttcaatgaagaccaaaagaaagcaattgagaccgcctatagcatggtgatg
ctgcatccgtcactccctagaatctgtttgattcacggaccacctggaacagggaaatca
agaacgattattggtctcttgcatcgcatcctgaatgagacacctaaggagagaccggct
ccgaacttgaacgccaaaattaaacgaaaccgtgtcttagtgtgtgcaccctccaatgcg
gccatcgatgaacttatgaaaaagatcattcttgaatttaaagaaaaatgccaaaacaag
aagagccctttgggaaattgtggagatataaatttagtgcgactgggtccagaaaagtcc
atctccagtgaggtcttgaaatttagcctggacagccaagttaactacagaatgaaaaag
gccttgcccagtcgtgatcaagatcttcacaagcgaaaggaagctctggatcaccagctg
gaccaactttctcgccagcgtgctatggaccgatgtgagaaaggagagaagagccaaaat
ttagatgaagaaatcgccagactctcagcgcagagagaacaactggcttctaaactaaaa
gaggttcgaggccgccctcaggaaatacaaagcaacatcatcctgggatcacacatcatc
tgctgcaccctgagtacaagcggaggttttttgctggaatctgcttttcgtcgacaagga
tatgaacctttcagttgcgtcattgttgatgaggctggacaggcttgcgaattggagaca
ttgattcccctcatccatcgctgcaacaagctcgtcctggttggagatcctaagcagctc
cctcccacaatcatctctctgaaggcgcaagagtttggctttgaccagtctatgatggct
cgtttgtgtaaaaacctggagaatcaggtggagcagaatctggccaggaaagcgcctatt
ttgcagctcacctttcaatatagaatgcatcctgacatatgcctgttcccatctaactat
atttatggccgaagcttgaaaactagcagagcgaccgaagaggcccgctgttcactggac
tggccgttcctgccttaccttgtgtttgacgtggaagacggtctggagcggcgggagcac
gaatcctattttaatttccaggaaataaagctagtgattgagttgattaagatgattaaa
gataaagagaaggatattacttctcggaacatcggcgtaatcacaccttacaagtcgcag
aagaagatgattcaatgtgaattggataaggagtttgaaaaaatcaggctaggggaggtt
gacaccgttgatggattccagggtcgtcagaaggactgcattattgttacctgtgttaga
gcaaactccacccaagacatcgggtttctgtcaagtgtgcagcgactgaacgttaccatt
acccgagccaagtatagcctcttcatcctcgggcatttgaaaacactgatggaaaacaaa
gattggagccagttgattcaagatgcccagaggcggggtgccatcattagaacctgtgaa
gccaactacaggcaagacgttcgtagaatcctgaagcccaaattggtgtcacagcaactt
ccactcaaggcagctgaagagaaaactagaccccaagccgtcttgtccggtgagaaaccg
aaggatacggcagagggcttggagaatatcacctctagccccaccatcgcaccctccctc
ccttctcctcagtgtggcggcccttccaaccgagcagaaccaccgcctcccgaccaccag
aagaaaggtgcgcaggctgctccgggaaaagcgcttattacatctcctgctcagaatcaa
ccccgggacccaagattggcttggagaagagacttttcagccaaagagaggcccccgaag
gagcctacggcctacccccggcaagagcttagcggtcttggagcggacccgggccagagt
aggatcctagaccactctgtctctaaagtagcagccagaaccctgagcaacccccagcca
gatggtccgtcaacccaggggtccggccagagcacccagaaaagccgacatcaaagttgg
gagggttccagaagagaaacaccatctcctcggagaggagggcaggagaaacaggccccc
agaagagacaagtactctgacttagatagagactatcgcttggagcggggctctcattcg
aaaaaggacttccgcccgggcagggtccaggacacccaagagaatcgagacagtgatgca
aagaggaggaaagtttcttag
DBGET
integrated database retrieval system
