Tachyglossus aculeatus (Australian echidna): 119933728
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Entry
119933728 CDS
T10703
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu01521
EGFR tyrosine kinase inhibitor resistance
tacu04151
PI3K-Akt signaling pathway
tacu04217
Necroptosis
tacu04380
Osteoclast differentiation
tacu04550
Signaling pathways regulating pluripotency of stem cells
tacu04620
Toll-like receptor signaling pathway
tacu04621
NOD-like receptor signaling pathway
tacu04630
JAK-STAT signaling pathway
tacu04658
Th1 and Th2 cell differentiation
tacu04659
Th17 cell differentiation
tacu05140
Leishmaniasis
tacu05145
Toxoplasmosis
tacu05152
Tuberculosis
tacu05160
Hepatitis C
tacu05161
Hepatitis B
tacu05162
Measles
tacu05163
Human cytomegalovirus infection
tacu05164
Influenza A
tacu05165
Human papillomavirus infection
tacu05166
Human T-cell leukemia virus 1 infection
tacu05167
Kaposi sarcoma-associated herpesvirus infection
tacu05168
Herpes simplex virus 1 infection
tacu05169
Epstein-Barr virus infection
tacu05171
Coronavirus disease - COVID-19
tacu05200
Pathways in cancer
tacu05203
Viral carcinogenesis
tacu05212
Pancreatic cancer
tacu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
119933728 (JAK1)
04151 PI3K-Akt signaling pathway
119933728 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
119933728 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
119933728 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
119933728 (JAK1)
04621 NOD-like receptor signaling pathway
119933728 (JAK1)
04658 Th1 and Th2 cell differentiation
119933728 (JAK1)
04659 Th17 cell differentiation
119933728 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
119933728 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119933728 (JAK1)
05203 Viral carcinogenesis
119933728 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
119933728 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
119933728 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
119933728 (JAK1)
05161 Hepatitis B
119933728 (JAK1)
05160 Hepatitis C
119933728 (JAK1)
05171 Coronavirus disease - COVID-19
119933728 (JAK1)
05164 Influenza A
119933728 (JAK1)
05162 Measles
119933728 (JAK1)
05168 Herpes simplex virus 1 infection
119933728 (JAK1)
05163 Human cytomegalovirus infection
119933728 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
119933728 (JAK1)
05169 Epstein-Barr virus infection
119933728 (JAK1)
05165 Human papillomavirus infection
119933728 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
119933728 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
119933728 (JAK1)
05140 Leishmaniasis
119933728 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
119933728 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tacu01001
]
119933728 (JAK1)
Enzymes [BR:
tacu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119933728 (JAK1)
Protein kinases [BR:
tacu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
119933728 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
FERM_F1
ABC1
SH2
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
119933728
NCBI-ProteinID:
XP_038609228
LinkDB
All DBs
Position
10:complement(4253196..4382733)
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLTIEEDCNAMAFCAKIRSSKKSDVSLEAPEPGLEIAFYLSERAPLRCSSGQFTAEQL
CIRAAQECGISPLCHNLFALYDESSKLWHAPNHTVTIDDKTSLRLHYRMRFYFTNWHGTN
ENEQSVWRHSPRKQKNGYEKRAVQDGTPLLDANSLEYLFAQGQYDLVKCLAPVRDPKTDQ
EVHEIENECLGMAVLAISHYAKKKNMQLPELSKDISYKRYIPETLNRTIRQRNMLTRMRI
NNVFKDFLKEFNNKTICDSSVSAHDLKVKYLSTLETLTKHYGAEIFEATLLQISSENEKN
RSHFGDHGEVLHFEVMVTGNQGIQWRQKSNIAPVEKEKSKPKRKKLESKTKKEEEKIKLR
EEWISFSYFPEITHIVIKESTVSINKQDNKRMELKLASHAEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAVNKLRQEGNEDGMYVLRWSCTDFDNILMTVA
CFENAQQVVTGAKQYKNFQIEVRQGKYSLHGSDRAFPSLRELMDHLKKQILKTDNISFML
KRCCQPKPREISNLLVATKKAQEWQPVYTMSQLSFHRILKEEIVQGEHLGRGTRTQIYSG
TLDYRDDEGSADEKKMKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEFGPLDLFMHRKSEALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNIL
LAREGIDAECSPFIKLSDPGIPITVLSRQERVERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLVEKERFYEGQFMPVTPSCKELADLMKQCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGSGIKLIMEFLPS
GSLKEYLPRNKSKINLNQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESENRVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLLQCKFYIASDVWSFGVTLHELLTYCDSD
ASPMAMFLKMIGPTQGQMTVTRLVCALKEGKRLPCPTNCPEEVYQLMGKCWEYHPTKRTT
FQSLIQSFEGLMK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaactatcgaggaggactgcaatgccatggctttctgcgcaaagatcagg
agctcgaagaagagcgacgtgagcctggaggccccggagcccggcctggagatcgctttc
tacctgtccgagcgcgccccgctccgctgctccagcggccagttcaccgccgagcagctg
tgcatcagagccgcgcaggagtgtggcatctcgcccctgtgccataacctcttcgccctg
tacgacgagagctccaagctgtggcacgcgccgaaccacacggtcaccatcgatgacaag
acgtccctgcggctccactaccgtatgaggttctacttcaccaactggcacggcaccaac
gagaacgagcagtccgtgtggcggcactcgccccgcaagcagaagaacggctacgagaag
cgggcggtccaggatggcacgccgctcttggatgccaactccctggagtacctgttcgcc
caggggcagtacgacttggtgaagtgcctggccccggtccgggaccccaagacggaccag
gaggtgcacgagatcgagaacgagtgcctgggaatggccgtcctggccatctcgcactac
gccaaaaagaagaacatgcagctgccggagctgtccaaggacatcagctacaagcgctat
atcccggaaacgctgaacaggaccatcaggcagaggaacatgctcaccaggatgcggatc
aacaacgtgttcaaggatttcctgaaggagttcaacaacaagaccatctgcgacagcagc
gtgtcggcgcacgacctgaaagtcaagtacctgtccaccctggagacgctcaccaagcat
tacggggccgagatcttcgaggcgacgctgctgcagatttcctcggaaaacgagaagaac
aggtctcacttcggggaccacggggaggtccttcacttcgaggtgatggtgaccggcaac
caagggatacagtggcggcagaagtccaacatcgcgcccgtcgagaaggagaaaagcaag
ccgaagaggaagaaactggaaagcaagaccaagaaggaggaggagaaaatcaaactccgg
gaggaatggatcagcttctcctacttccccgaaatcacccacatcgtcataaaggagtca
accgtcagcatcaacaaacaggacaacaagcgcatggagctgaagctggcctcccacgcg
gaggccctgtccttcgtgtcgctggtggacggctacttccggctcacggcggacgcccac
cactatctctgcacggacgtggcccccccgctcatcgtccacaacatccagaacggctgc
cacgggcccatctgcaccgaatacgccgtcaacaagctgaggcaggagggcaacgaggac
gggatgtacgtgctgcgctggagctgcaccgacttcgacaacatcctcatgaccgtggcc
tgcttcgagaacgctcagcaggtggtcaccggcgccaagcagtacaagaacttccagatc
gaagtgcggcagggcaagtacagcctgcacggctccgaccgggccttcccctccctgcga
gaactcatggaccacctcaaaaagcaaatcctcaagaccgacaacatcagcttcatgttg
aagagatgctgccagcccaagccccgagagatctccaacctgctggtggccacgaagaag
gcgcaggaatggcagcccgtctacaccatgagccagctcagcttccaccgcattcttaaa
gaggagattgtccagggcgaacatctcggccgggggacccggacccagatctattcgggg
actctggactacagggacgacgaagggagcgcggacgagaagaagatgaaagtcatcctc
aaagtcctggaccccagccacagagacatctctctggctttcttcgaagcggccagcatg
atgcggcaagtctcgcacaaacacatcgtctacctctacggcgtctgtgtccgcgacgtg
gaaaacatcatggtggaggagttcgtggagttcgggcccctggatctgttcatgcaccgc
aagagcgaggctctgaccaccccctggaagttcaaggtggccaaacagctggccagcgcc
ctcagctacttggaggacaaagacttggtccacgggaacgtgtgcaccaagaacatcctc
ctggcgcgcgaggggatcgacgccgagtgcagtcccttcatcaagctgagcgacccgggc
atccccatcactgtgctctccaggcaagagcgcgtggagcggatcccgtggatcgccccc
gagtgcgtcgaagactccaaaaacctgagcgtggcagcggacaagtggagcttcggcacg
acgctgtgggaaatctgttacaacggcgaaatccccctcaaggacaagacactagtggag
aaagagcggttttatgaaggacagttcatgccggtcacgccgtcttgcaaggagctcgcc
gacctgatgaagcagtgcatgaactacgaccccaaccagaggcccttcttcagagccatc
atgagagacattaacaagctggaggagcagaacccggacatcgtttcggagagaaagccg
gccacggaggtggaccccacccacttcgagaagcgcttcttgaaacggatccgtgacctg
ggggagggccactttgggaaggtggagctgtgcaggtatgacccggaaggagataacacc
ggcgaacaggtggcggtcaagtccctgaagcccgagagtggcggcaaccacatagccgac
ctgaagaaggagatcgagatcctcaggaacctctaccacgaaaacatcgtcaagtacaag
gggatctgcactgaagacgggggaagtgggattaagctcatcatggagttcttgccttcc
ggaagcctcaaggagtaccttcccagaaacaagagcaaaatcaacctgaatcagcagctg
aaatacgccgttcagatttgtaaggggatggattatctgggatcgcggcagtacgttcac
cgggatttagccgcgagaaatgtcctggttgagagtgaaaaccgagtgaagattggtgac
tttggtttgaccaaagcgatcgaaacggataaggaatattacacagtcaaggatgaccgt
gacagcccagtgttctggtacgccccggagtgtctgctgcagtgcaagttctacatcgcc
tccgacgtctggtccttcggcgtgacgctccacgagctgctcacctactgcgactcggac
gccagccccatggcgatgttcctcaagatgatcggcccgacccaaggccagatgaccgtc
acgcgcctcgtctgcgccttgaaagaagggaaacgcttgccctgccctaccaactgtccc
gaggaggtctaccagctgatggggaaatgctgggagtaccaccccaccaaacgcaccacc
ttccagagcctcatccagagctttgaaggacttatgaaatga
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integrated database retrieval system
