Tachyglossus aculeatus (Australian echidna): 119934338
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Entry
119934338 CDS
T10703
Symbol
HSD17B2
Name
(RefSeq) 17-beta-hydroxysteroid dehydrogenase type 2
KO
K13368
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:
1.1.1.62
1.1.1.239
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00140
Steroid hormone biosynthesis
tacu01100
Metabolic pathways
tacu04913
Ovarian steroidogenesis
Module
tacu_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
119934338 (HSD17B2)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
119934338 (HSD17B2)
Enzymes [BR:
tacu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.62 17beta-estradiol 17-dehydrogenase
119934338 (HSD17B2)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
119934338 (HSD17B2)
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Motif
Pfam:
adh_short
adh_short_C2
KR
SDR
Epimerase
DUF1776
NmrA
NAD_binding_10
GDP_Man_Dehyd
Motif
Other DBs
NCBI-GeneID:
119934338
NCBI-ProteinID:
XP_038609728
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Position
11:38641560..38671738
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AA seq
390 aa
AA seq
DB search
MNAFFSAAGLLSLGATAVFGGIVLYKLEKNHGKIGNKAIYSIALLFLGEVYCFSSLSYFW
GFSLFSLACIISHIYLSGQEMLPVDQKAVLITGGDSGIGHTLVKHLDELGFTVFAGVLNE
KGPGAEELRRSCSERLTVLQMDVTDSAQLKEAHRRVLAKVKGTGLWAVVNNAGIIGFPGD
GELTSMNIYRQCMDVNFFGAVEVTKTFLPLLRKAKGRLVNISSMAGSSPLPNFSAYGSSK
AALTMFSGVTRLELSRWGVKVTLIQPGGFRTNIQGSPDQWEAQEKDLLENLQEDVKEDYG
KDYIQALKSVLKSMSKSSSTDLSPVVFAVLHAILSKHSLALYTPGTKSYLTLCLSSFFPI
WVSDAFFKKLFSLRILPKALQKPDPPNKKL
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaatgctttcttctctgcagcgggcttgctttccttgggtgcaactgcagtgtttgga
ggaatagtgctgtataaactggagaagaaccatggcaagatagggaataaggctatttac
agtatagctctccttttcttgggtgaagtgtactgcttttccagcctgtcatatttttgg
ggcttcagtttgttctctctggcatgcatcatctcccacatctatttatctggtcaagaa
atgttacccgtggatcaaaaagcagtactaatcacaggtggagattcagggattggccac
acactggtgaaacacctggatgagttgggtttcacagtatttgctggcgttttgaatgaa
aaaggacccggagcagaagaactcagaaggagctgctccgagcgactcacggttctccag
atggatgtcaccgactctgctcagctgaaggaagctcacagacgggttttggcaaaggtg
aagggcacaggactgtgggcggttgtcaacaatgctgggataattggattcccaggagat
ggtgaattaacttccatgaatatttacagacagtgcatggatgtgaacttctttggagcc
gtagaggtcacaaagacattcttacctttactccggaaagccaaagggaggcttgtaaat
ataagcagtatggcaggaagcagccccttgccaaatttctccgcatatggctcgtcgaag
gctgctctgaccatgttttcgggcgtaacaagactggagctttccagatggggggtaaag
gtaactttaattcaaccaggaggcttcagaacaaatatccaaggctcaccggaccagtgg
gaggcacaagaaaaggatctcctggagaacctccaagaagatgtcaaggaagactatggc
aaagactatattcaagccctgaaaagtgttctaaaatccatgagcaagtcctccagtacc
gatctctcgccagtggtctttgctgttctccatgccatcctgtccaagcattctcttgcc
ttatacactccggggacaaaatcttatctgaccctctgtctttcttctttcttccccatc
tgggtttctgatgccttttttaagaaactcttcagcctcagaatactgcccaaagcttta
caaaaacctgatcctccaaataaaaaactttag
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