Tachyglossus aculeatus (Australian echidna): 119934772
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Entry
119934772 CDS
T10703
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00562
Inositol phosphate metabolism
tacu01100
Metabolic pathways
tacu01521
EGFR tyrosine kinase inhibitor resistance
tacu04012
ErbB signaling pathway
tacu04014
Ras signaling pathway
tacu04020
Calcium signaling pathway
tacu04062
Chemokine signaling pathway
tacu04064
NF-kappa B signaling pathway
tacu04066
HIF-1 signaling pathway
tacu04070
Phosphatidylinositol signaling system
tacu04072
Phospholipase D signaling pathway
tacu04360
Axon guidance
tacu04370
VEGF signaling pathway
tacu04380
Osteoclast differentiation
tacu04611
Platelet activation
tacu04613
Neutrophil extracellular trap formation
tacu04625
C-type lectin receptor signaling pathway
tacu04650
Natural killer cell mediated cytotoxicity
tacu04662
B cell receptor signaling pathway
tacu04664
Fc epsilon RI signaling pathway
tacu04666
Fc gamma R-mediated phagocytosis
tacu04670
Leukocyte transendothelial migration
tacu04722
Neurotrophin signaling pathway
tacu04750
Inflammatory mediator regulation of TRP channels
tacu04919
Thyroid hormone signaling pathway
tacu04933
AGE-RAGE signaling pathway in diabetic complications
tacu04935
Growth hormone synthesis, secretion and action
tacu05167
Kaposi sarcoma-associated herpesvirus infection
tacu05169
Epstein-Barr virus infection
tacu05170
Human immunodeficiency virus 1 infection
tacu05171
Coronavirus disease - COVID-19
tacu05200
Pathways in cancer
tacu05205
Proteoglycans in cancer
tacu05206
MicroRNAs in cancer
tacu05214
Glioma
tacu05223
Non-small cell lung cancer
tacu05225
Hepatocellular carcinoma
Module
tacu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
Enzymes [BR:
tacu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
119934772 (PLCG2)
Membrane trafficking [BR:
tacu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
119934772 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
119934772 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
119934772
NCBI-ProteinID:
XP_038610243
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Position
11:38485689..38571448
Genome browser
AA seq
1206 aa
AA seq
DB search
MNHVFPVDLIEIKEIRPGKNAKDFERGKATRQKDDCCFTIFYGTQFVLNTLSLAADSKED
ALKWLCGLKILTKEVKNAATPAITESWLRKQIYSVDQTRRNSISLREMKTILPLVNFKVG
SAKFLKDKFMEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDA
SAVHLHDFQRFLHTEQQEQWAQDLGKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSKE
NSIWDEKYDVVDVQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIEL
DCWDGPDGKPIIYHGWTRTTKIKFDDVVQAIKDHAFVTSDFPVILSIEEHCCVEQQRYMA
KVFKEVFGDALLMRPTEASADQLPSPTQLKEKIIIKHKKLGPRGDVDVNIEDKKEEKKQQ
GELYMWDSIDQKWYRHYCAIADEKLSFSDDIEQSVEEDSPKDVAQTDLHFGEKWFHKRME
KRTSAEKLLQEYCAETGGKDGTFLVRESETYPNDYTLSFWRSGRVQHCRIRSIVEGGTMK
YYLTDNLMFSSIYDLIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDDLSRGEAED
MLMRIPRDGAFLIRKREDADSYAITFRAKGKVKHCRINKDGRHFVLGTSAYFESLVELVN
YYEKHALYRKMKLRYPVTRELLERYNTERDINSLYDVRMYVDPSEINPSTPQRTVKALYD
YKAKQEDELSFCRGALIHNVLKEEGGWWKGDYGGRLQQYFPANYVEDISTVDFEELEKQI
IEDNPLGSLCRGILDLNAYNVVKAPQGRNQKPFVFILDPKKSDDPPVVFATDRVEELFEW
YQSIREITWKNTTVENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREVRSFV
ETKADTIVRQRANELLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADK
YMQMNHALFSLSGRTGYVLQPESMRNENYDPTPSESQRKMLMTLTVKVLGARHLPKLGRS
IACPFVEVEICGAEYDNNKFKTTVVNDNGLNPVWAPTHEKVTFEIYDPTLAFLRFVVYEE
DMFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSS
CRQLRRRQEELNNQLFLYDTHQNLRNANRDALVNEFNVNENQLQLYQERCDRRLREKRVS
NSKFYS
NT seq
3621 nt
NT seq
+upstream
nt +downstream
nt
atgaaccatgtttttccagtggatctgattgaaatcaaggaaatccgtccagggaagaac
gcaaaggacttcgagcgtgggaaagccacccgccagaaggatgactgctgcttcactata
ttctatggaacccagtttgttctcaacacactaagtttagcagctgattccaaagaggat
gcattgaagtggctctgtggcttgaagatcttaaccaaggaagtcaagaatgcagcgacg
ccggcgattaccgagagctggctaagaaagcagatttattctgtggatcaaaccaggaga
aatagcatcagcctcagagaaatgaagactatactacccttagtaaacttcaaagtaggc
agtgccaagttcctgaaggataagtttatggaaataggagctcacaaggacgaacttagc
tttgagcagttccatttgttctataaaaaacttatgtttgaacaacagaaatcaatcctt
gatgaattcaaaaaggattcttcggtgttcatcctgggaaatacagaccggccggatgcc
tcagctgtccacctgcatgacttccagaggtttctgcacactgaacagcaggaacaatgg
gcacaagatcttggtaaagtccgggaacgaatgacaaagtttattgacgacactatgaga
gaaactgccgagccgtttttatttgttgatgagttcctcacctaccttttttcaaaagaa
aatagcatctgggatgaaaagtatgacgtggtagatgttcaggatatgaacaatccttta
tctcattattggatttcttcatcacataacacgtacctcaccggggaccagctccgaagt
gaatcttccccggaagcctatatcaggtgcctgcggatgggatgccgatgcattgagttg
gactgctgggatggccctgatggaaagccaatcatctatcatggatggacacggaccacg
aagatcaagtttgatgatgtggtacaggccatcaaagaccatgcttttgtgacctcagat
ttcccggtgatcctctctatcgaagagcactgctgtgtggagcagcagcgctacatggca
aaggttttcaaggaggtatttggggatgccctcctcatgcggcccaccgaagccagtgcc
gatcagttgccgtccccgacccagctgaaagagaaaatcatcatcaagcataaaaagctg
ggcccgagaggagatgtggatgtcaacatagaagacaagaaagaggagaagaagcaacaa
ggggaactgtacatgtgggattccatagatcagaaatggtatcggcattattgtgccatc
gcagatgagaagctttctttcagtgatgatatagagcagagcgtggaggaagattcccca
aaggatgtagcccagactgatctgcattttggtgaaaagtggtttcacaagagaatggag
aagaggacaagtgctgagaagctgcttcaggaatactgcgcagaaactgggggcaaagac
ggaaccttcctagtccgggaaagtgaaacatatcccaatgactacacactgtcattctgg
agatctggccgagtccagcactgccgcattcggtccatcgtagagggcggcaccatgaag
tactacctgactgacaacctcatgttcagcagcatctacgacttgatccaacactatcgg
gaggctcacctgcggtgtgccgagttcgagctgcgtctaaccgatccggtgcccaacccc
aacccgcatgaatccaaaccctggtattacgacgacttgagccgaggagaagctgaagac
atgctgatgcgaattccccgagatggagcctttctgattaggaaaagagaagacgcagat
tcgtacgccattacgttcagggcaaagggaaaagtgaagcactgtcggattaataaagac
gggcgccattttgtcctgggaacttcagcctactttgaaagtttggtggagctggttaac
tactatgaaaaacacgcactctacagaaaaatgaaactgcgctatccagtgacgcgggag
ctgctggagcgttataacacggaaagggatataaactcactttatgacgtcaggatgtat
gtggaccctagtgagattaatccttcaacgcctcagagaactgtgaaggctttatatgac
tacaaagctaaacaagaagatgaactgagcttttgcaggggagccttgattcacaatgta
ttgaaggaagaaggaggctggtggaaaggggactacggtggaaggcttcagcagtatttt
ccagcaaattatgttgaagacatatcaacagttgactttgaagagcttgaaaagcagatt
atcgaagacaatcctttagggtctctgtgcaggggcattctggacctcaatgcctataat
gttgtgaaagccccacaaggcagaaatcaaaagcctttcgtctttatcttggaccccaag
aagtccgacgaccctccagtcgtgttcgcgactgacagagtggaagaactgttcgagtgg
taccagagcatccgagagatcacctggaagaatacaactgtggagaacaacatgaagtac
tgggagaagaaccagtccattgccatagaactgtccgacctggtcgtctactgcaaacca
actagcaaaaccaaggataatttggaaaatcctgacttccgggaagtacgttcttttgtg
gaaactaaggccgacaccatcgtcaggcagagggcaaatgagctcttgaaatacaatcaa
aagggactgactcgagtttaccctaaaggacagagagtcgactcctccaattacgacccc
tttcgtctgtggctctgcggctctcagatggtggctttgaatttccagacagcagacaaa
tacatgcagatgaaccacgccctattctccctcagtgggcggaccggatacgtcctgcag
ccggaaagcatgagaaatgaaaactacgacccgacgccatcggaatcgcagcgaaaaatg
ctcatgactctgacggtgaaggtccttggggctcgccacctgcccaaacttggcagaagc
atcgcctgcccatttgtggaggtggaaatctgtggggccgaatacgataacaataaattc
aagacaacggttgtgaatgataatggtcttaatcccgtctgggctcccacacatgagaaa
gtgacgtttgagatttacgatcccactttggccttcctgcgttttgtggtttatgaggaa
gatatgttcagtgatcccaacttccttgctcatgccacgtaccccatcaaaggaatcaaa
tcagggttcagatccgtccctctcaaaaatggttacagtgaggacatcgagctagcttcc
ctgttggttttctgtgagatgcgcccagttctggaaagcgaggaggagctctactcgtca
tgccgccagctgcgaaggcggcaagaagaactgaataaccagcttttcctttacgacacc
caccaaaacttgcgaaacgccaaccgagacgctctggtgaatgagttcaatgtaaatgag
aatcagctgcagctgtatcaggagaggtgcgacaggagattaagggagaagagagtcagt
aacagcaagttctactcatag
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