Tachyglossus aculeatus (Australian echidna): 119939404
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Entry
119939404 CDS
T10703
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00230
Purine metabolism
tacu01100
Metabolic pathways
tacu04022
cGMP-PKG signaling pathway
tacu04024
cAMP signaling pathway
tacu04924
Renin secretion
tacu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119939404 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
119939404 (PDE3A)
04022 cGMP-PKG signaling pathway
119939404 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
119939404 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
119939404 (PDE3A)
Enzymes [BR:
tacu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
119939404 (PDE3A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
DUF6171
Motif
Other DBs
NCBI-GeneID:
119939404
NCBI-ProteinID:
XP_038615344
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Position
2:174568136..174808909
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AA seq
862 aa
AA seq
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MDFLQEGSASPEQEWKKRSAELAGHPEWEHRRGPRGSQGSGTSVPVDIAVMGEAHGLITD
LLADPSLPPNVCTSLRTVSNLLSAQLTFPALHKARPAPAPGTLPACSEGLLGSDTEDGPD
REKPAIPKRLRKSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKAHEGPSSI
STTNPEAWNSSVLMTLTKSRSFSSSYAVSATNHLNAKRQVRAGLLAKISPLSSPCPSPVQ
GTPSSSPVSKSSGGQFPDSADAAGQQVLNSHKALAYTQSAPDLSSQGPPTPPAICSSCGR
SFSQANTTDAQLERNASGISSPGRTDDAAQVTSDYETNNSDSSDIVQNEDEVEASKEPLR
KGSPCSPYAPEAVIFMDKPILAPEPLVMDNLDSLMGQLNTWNFPIFDLVEKIGRKCGRIL
SQVSYRLFEDMGLFEAFKIPVKEFMNYFHALENGYREIPYHNRIHATDVLHAVWYLTTQP
VPGLSTSLNDHGSASDSDSDSGVPHGHTGYVFSKMYMAGEERSGCLAGHIPALELMALYV
AAAMHDYDHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWSLFMSHPEYNFLINLDH
VEFKHFRFLVIEAILATDLKKHFDFVAKFNAKVNEEVGIDWANENDRLLVCQMCIKLADI
NGPAKCKELHLQWTDGIVNEFYQQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGP
LCHSYDSAGLMPGKWVEDDADGSELEGDPDAHPEDGEEEEDDDGQSTPEGEAGENAESSR
KPKFQRRKIHCQITQHLLQNHKMWKQEIEREQRLSGAGGRGKGGPDAPGPAQPAEAIQAI
TEEDEDRGKGQAEESSTAQPAQ
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atggatttcctccaagagggctccgcatctccggaacaggagtggaagaagcgaagtgca
gagctggcaggtcaccctgaatgggagcacaggcgaggacccaggggatcccagggttcg
gggacgagcgtgccggtggacatcgcggtgatgggggaggcccacgggctgatcacggac
ctgctggcggacccctcgctgccgcccaacgtgtgcacgtctctgcggaccgtcagcaac
ctgctgagcgcccagctcaccttcccggccctgcacaaggcccggcccgcgcccgcaccc
gggaccctgcccgcctgctccgagggcctgctcggctccgacaccgaggacggaccggac
cgggagaagccggccattcccaagcgcctgaggaagagtctcccgccggggctgctgagg
cgcgtctcatccacgtggaccacgacgacttcggccacgggcctgcccaccctggagcca
gcccccgtgaggagagaccgcagcgccagcatcaaagcccacgaggggccttcttccatc
agcactactaatcccgaggcatggaacagctccgtcctgatgaccctcaccaaaagtcgg
tcattctcttcgtcctatgccgtgtccgccacaaaccacctgaatgccaagcggcaggtc
cgagcgggtctcctagcgaaaatttccccgctgtcatccccgtgcccctcgccggtccag
ggcaccccctccagcagccctgtcagcaagagctcgggtggccagtttccggactcagcc
gacgcagccggccagcaagtcctcaactctcacaaggccttggcctacacccagagcgcc
cctgacctttcatcccagggcccgcccacaccccctgccatctgcagcagctgcggaaga
tcatttagccaagccaatactacggatgcacagttggagaggaatgcttcagggatttct
tccccgggcaggacagatgatgcagcgcaagtgacctcggactacgaaaccaacaacagc
gacagcagtgacatcgtccaaaatgaggatgaggtggaggcctccaaagagccactgaga
aaggggtcaccctgcagcccgtacgccccagaggctgtcatcttcatggacaaacccatt
cttgctccggaacccctcgtcatggataatttggattcattaatggggcagctaaacact
tggaattttcccatcttcgatttggtggaaaagatcggacgcaagtgtggccggatcctc
agtcaggtgtcctacaggcttttcgaagacatgggactttttgaagcttttaaaattcca
gtgaaggaattcatgaactactttcacgccctagagaatgggtatcgagagatcccttac
cacaacagaatccacgccaccgacgtgctgcacgctgtgtggtacctcaccacccagccc
gtgcccggcctgtccaccagcctcaatgaccatggatcggccagtgattcagactcggac
agcggggtcccgcacggccacacgggctacgtcttctccaagatgtacatggcgggcgag
gagcggtccggctgcctggccgggcacatccctgccctggagctgatggccctctacgtg
gccgccgccatgcatgactatgaccacccaggaaggaccaacgccttcctcgtggccacc
agtgccccccaggccgtgctatacaacgaccggtcggttttggagaaccaccacgccgcc
gccgcctggagcctcttcatgtctcacccagagtataatttcctcatcaacctcgaccat
gtggagttcaaacatttccgcttccttgtcatcgaagccattttggccactgatctgaag
aaacacttcgacttcgtggcaaaattcaatgccaaggtgaacgaagaagtcgggatcgac
tgggccaacgagaacgaccgcctgctggtctgccagatgtgcataaaactggccgacatc
aacggccccgccaagtgcaaggaactccaccttcagtggacggacggcatcgtcaacgag
ttttaccagcagggtgacgaagaggccagcctgggccttcccatcagcccgttcatggac
cgctcggctcctcagctggccaacctccaggagtccttcatctcccacatcgtggggccg
ctgtgccactcctacgactcggccggcctgatgcccgggaagtgggtggaggatgacgcc
gacggcagcgagctggagggcgaccccgacgcccaccccgaggacggggaggaggaagag
gacgacgacgggcagagcacccccgaaggggaagctggcgaaaacgccgaatcctcaaga
aagccgaagttccagaggaggaaaattcactgccagatcacgcagcacctgctgcagaac
cataagatgtggaagcaggagatcgagagagagcaacgcctgagcggggccgggggccgg
ggcaagggcggaccagacgccccgggcccggcccagccggcagaagccatccaagccatc
acggaggaggatgaagacagagggaaagggcaggcagaggagagctccactgcccagccg
gcccagtga
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