KEGG   Tachyglossus aculeatus (Australian echidna): 119941951
Entry
119941951         CDS       T10703                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3 isoform X1
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
tacu  Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04010  MAPK signaling pathway
tacu04015  Rap1 signaling pathway
tacu04218  Cellular senescence
tacu04620  Toll-like receptor signaling pathway
tacu04664  Fc epsilon RI signaling pathway
tacu04668  TNF signaling pathway
tacu04714  Thermogenesis
tacu04750  Inflammatory mediator regulation of TRP channels
tacu04912  GnRH signaling pathway
tacu04935  Growth hormone synthesis, secretion and action
tacu04936  Alcoholic liver disease
tacu05014  Amyotrophic lateral sclerosis
tacu05022  Pathways of neurodegeneration - multiple diseases
tacu05132  Salmonella infection
tacu05135  Yersinia infection
tacu05145  Toxoplasmosis
tacu05161  Hepatitis B
tacu05169  Epstein-Barr virus infection
tacu05170  Human immunodeficiency virus 1 infection
tacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tacu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119941951 (MAP2K3)
   04015 Rap1 signaling pathway
    119941951 (MAP2K3)
   04668 TNF signaling pathway
    119941951 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    119941951 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    119941951 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    119941951 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    119941951 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    119941951 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    119941951 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    119941951 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    119941951 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    119941951 (MAP2K3)
   05161 Hepatitis B
    119941951 (MAP2K3)
   05169 Epstein-Barr virus infection
    119941951 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119941951 (MAP2K3)
   05135 Yersinia infection
    119941951 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    119941951 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    119941951 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    119941951 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119941951 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    119941951 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tacu01001]
    119941951 (MAP2K3)
Enzymes [BR:tacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     119941951 (MAP2K3)
Protein kinases [BR:tacu01001]
 Serine/threonine kinases: STE group
  STE7 family
   119941951 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Haspin_kinase Choline_kinase Seadorna_VP7 APH DUF4344 RIO1
Other DBs
NCBI-GeneID: 119941951
NCBI-ProteinID: XP_038618455
LinkDB
Position
21:56343570..56414964
AA seq 335 aa
MDKKQGKPKKRKDLKIVPIKPPVSNPTPPRNLDSRTFITIGDKNFEVEADDLVTISELGR
GAYGVVEKVRHAQSGTIMAVKRIRATVNTQEQKRLLMDLDISMRTVDCFYTVTFYGALFR
EGDVWICMELMDTSLDKFYKKVLEKKMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVK
PSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVW
SLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADHFSPEFVDFTAQCLRKNPAE
RMSYLELMEHPFFNLHKTKETDIAAFVIEILGEDS
NT seq 1008 nt   +upstreamnt  +downstreamnt
atggacaagaaacaaggaaaacccaagaaaaggaaggatttaaaaatagtccccatcaag
ccaccagtttccaaccccacgcctccccggaacctggactccaggaccttcattaccatc
ggggataagaattttgaagtggaggccgatgacttggtgaccatctcggaactgggtcgg
ggggcgtatggagtcgtggagaaagtacggcacgcgcagagtgggaccatcatggctgtc
aagaggatccgtgcaactgtgaacactcaggaacagaagaggctgctcatggacctggac
atttcaatgaggacagtggattgcttctacaccgtcacgttctatggagccctgttcaga
gagggtgatgtgtggatatgcatggagctgatggacacttccctggacaaattctacaag
aaggttcttgagaagaagatgacaatcccggaggacattttaggagagatcgcagtgtct
attgtgagagccctggagcatttgcacagtaaattgtcggttattcacagagatgtgaaa
ccttctaatgttctcatcaacaaggaaggtcatgtgaaaatgtgtgactttgggatcagt
ggctacttggtggactcagttgccaagaccatggatgccggttgcaagccctacatggcg
cccgagagaataaaccccgaactgaaccagaaaggttacaacgtcaagtctgatgtctgg
agtctgggaattaccatgatcgagatggccatcctccggttcccgtacgagtcctgggga
acccccttccagcaactgaagcaggtggtggaggagccctcgccccaactcccagcagac
catttctcccccgagtttgtggacttcacagcccagtgcttacggaagaaccctgctgag
cggatgagctacctagaacttatggaacaccccttctttaacttgcacaaaaccaaagag
actgacatcgctgccttcgtgatagagatcctgggggaggactcgtag

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