Tachyglossus aculeatus (Australian echidna): 119945141
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Entry
119945141 CDS
T10703
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00230
Purine metabolism
tacu00670
One carbon pool by folate
tacu01100
Metabolic pathways
tacu01523
Antifolate resistance
Module
tacu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119945141 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
119945141 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119945141 (GART)
Enzymes [BR:
tacu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
119945141 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
119945141 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
119945141 (GART)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
GARS_N
AIRS_C
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
Sacchrp_dh_NADP
RimK
Motif
Other DBs
NCBI-GeneID:
119945141
NCBI-ProteinID:
XP_038622097
LinkDB
All DBs
Position
24:24743624..24788197
Genome browser
AA seq
1083 aa
AA seq
DB search
MAAALRPPNSCSAGLRAPGKQRAGAAPSLAGGGRAAARPANGRARRRRFRTEGQGEGGGG
AVGEFAAAMLSAPDAVSSRVLVIGNGGREHALAWKLAQSQRVKHVLVAPGNAGTVNLEKI
SNAAISVSDHTELAQFCKDQEIDLVVVGPEAPLAAGIVGDLTAAGVRCFGPTAEAAQLEA
SKRFAKEFMDRHGVPTARWKAFTDAREACDFISSADFPALVVKASGLAAGKGVIVATNKE
EARKAVQEIMQDRAFGRAGDTVVIEELLEGEEVSCLCFSDGKTVAPMPPAQDHKRLMDGD
RGPNTGGMGAYCPAPQLSKDLFLTIKNAILQKTVEGMQQEGTPYVGVLYAGIMLTKDGPK
VLEFNCRFGDPECQVILPLLKSDFYEVIQSALEGQLSGCMPEWLEDSAAVSVVMASRGYP
GSYAKGLEITGFPEAKTLGLEVFHAGTTLKEGRVVTNGGRVLMVTAIRKDLVSAVETANK
GLAAIKFEGAVFRKDIGYRAIAFLKQSRGLTYKESGVDIEAGNALVKKIKPLAKATSRSG
CSVDLGGFAGLFDLKLAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDIL
AQGAEPLFFLDYFSCGKLDIDVAGAVITGIAEACRKAGCALLGGETAEMPGMYPPGEYDL
GGFAVGAMERDQKLPCLESIVAGDAVVGVASSGLHSNGFSLVRKIVEASSLCLSSPAPSG
CGSQTLGELLLTPTRIYCRPLLPVLRSGRVKALAHITGGGLLENIPRVLPDNLGVRLDAR
RWQIPAIFSWLQCQGRLSEEEMARTFNCGIGAVLVVQKDLAEQVLRELKEQEEEAWIIGS
VLTCPAGPPRVQVDHLIEAMQVNRSCSLTNGSLHSRVRDQPKKARVAVLISGTGTNLQAL
ITSTQEPTSSAQIVLVISNKAAVLGLERAERAGIPTRVIDHKLYKTRAEFDIAVDRVLEE
FSIELVCLAGFMRILSGPFVKKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVRITGCTVH
FVAEEVDSGQIILQEAVPVKRGDTVGTLSERVKEAEHRAFPTALQLVASGEVQLGPTGKI
VWN
NT seq
3252 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgccctccgtcctcccaactcctgctcagcgggcctgcgggctcccggcaag
cagcgcgcgggggcggcgccctcattggctggcggggggcgggcggccgcgcggccggcc
aatgggagggcacgccggcgacgtttccgcacggaggggcagggggaaggaggggggggc
gcggtgggcgagttcgcggccgccatgttgtcagcgcctgacgcagtgtcttcccgagtg
ctcgtgattggcaatggagggagagaacacgccctggcctggaaactggcgcagtctcag
cgtgtcaaacatgtcttggtcgctccgggaaatgcaggaacagtaaatctcgagaagatt
tcaaacgcagctatctcagtcagcgatcacactgaacttgctcagttctgcaaggaccag
gagattgacctcgttgtcgtcggtccagaagctcctcttgctgccgggatcgtgggagat
ctgacagcggctggggtgagatgcttcgggcccacggcggaggcagctcagctggaggcc
agcaaaaggtttgccaaagagtttatggaccgacacggggtcccgacggcgagatggaaa
gcgttcaccgacgcgcgggaggcctgcgacttcatcagcagcgcagactttcctgccctg
gttgtcaaggccagtggtctagctgctggaaagggagtgattgtagccacaaacaaagaa
gaagctcgcaaagcggttcaagagatcatgcaggatagggcttttggcagggctggagac
actgttgttatagaagaactcttagaaggagaagaggtgtcgtgtttgtgcttcagcgat
ggtaagaccgtggcccccatgccgccagcccaggaccacaagcgcctgatggatggagac
agaggcccaaatactggtgggatgggggcttattgccccgcgcctcagctatcgaaggat
ttatttttgaccatcaagaatgcaattcttcagaaaacagtggaaggcatgcagcaagag
ggtactccgtacgtgggagtgctgtatgccggaatcatgcttaccaaagatggcccgaaa
gttctggagtttaattgcagatttggggatccagagtgccaggtcatcctcccccttctc
aaaagcgatttttacgaagtgatccagtcagccttggagggccagctcagcggctgcatg
cccgagtggctggaggacagcgccgcggtgagcgtcgtcatggcgagccggggctatccc
ggcagttacgccaagggcttggagataacagggttcccggaggcaaaaactttagggctg
gaggtgttccatgcaggtaccaccctgaaagaagggagagtggtcactaacggaggcaga
gtcctgatggtgactgccatccggaaagacctggtgtcagctgttgagacggccaataaa
ggactcgcagcgatcaagtttgagggggccgtttttaggaaagacattggttatcgagcg
atagctttcctcaagcaatccagaggcctgacttataaggaaagtggagtggacattgag
gctggcaatgcactggttaagaagattaaacctttggccaaagccacctccagatcaggc
tgcagcgtggatcttggagggtttgccggtctctttgatttgaaactagctggtttcaaa
gatcctctgctagcatcggggacagatggcgttggaaccaaactgaagatcgcccagctg
tgtaacaaacacgacactatcggtcaagatttggtggccatgtgtgtcaatgacattctg
gcccaaggggcagaacccctcttcttcctcgactacttttcctgtggaaaactggacatc
gacgtggcaggcgccgtcatcaccggaatagcggaagcgtgtcggaaggctggctgtgct
cttctgggaggcgagacggccgagatgcccgggatgtatcctccaggggaatacgacctg
ggaggctttgccgtcggagccatggagcgggaccagaaacttccttgcctggagagcatc
gtcgccggggacgccgtcgtcggagtggcttcctccgggcttcacagcaacgggttcagc
ctcgtgaggaaaatcgtggaggcgtcttccctctgcctctcctccccggctcctagtgga
tgtgggagccagactctgggggagctgctgctgaccccgacccgaatctactgccgcccg
ttgctaccagtcctgcgttccggacgcgtcaaggccctggcccacatcactggagggggg
ctgctggaaaacatccccagggtcctccctgacaacctgggagtgcgcttggacgctcgt
cgctggcaaatccccgccatcttctcgtggctgcagtgccaggggcgcctctcggaagaa
gagatggctcggacctttaactgcggcatcggggccgtcctcgtggtccagaaggacctg
gcggagcaggtgctgcgggaacttaaagagcaggaggaggaggcctggatcattggcagc
gtgctcacttgtcctgcaggtcctccccgcgtccaggttgatcatttgatcgaagccatg
caggtaaacaggtcatgttcattgacaaatggttccctgcacagccgcgtgcgtgaccag
ccgaagaaggcgagggtggctgtcctgatatctggaacgggtaccaacctccaagcgcta
ataaccagtacccaagaaccaaccagctctgcacaaatagtccttgtcatctctaacaaa
gcagctgtgcttgggctagagagggccgaaagggctggaattcctaccagagtcattgat
cacaaattatataagacgcgcgccgagtttgacatcgcagttgaccgagtcttggaagag
ttctccattgagctggtctgtctcgcgggtttcatgaggatcctgtctggcccctttgtc
aaaaagtgggatgggaaaatgctgaacatccacccttccttgctgccgtctttcaagggt
tcaaatgcccacgaacaagccctcgaagcgggcgtcagaatcaccggctgcaccgtgcac
tttgtagccgaagaagtagattctggacagatcatccttcaagaggctgtccccgtaaag
aggggtgacacggtgggtaccttgtcggaacgagtcaaggaggcggaacacagagccttt
cccaccgccctacagctagtggcaagtggagaagtccagctggggccaaccggcaagatc
gtttggaattga
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