KEGG   Tachyglossus aculeatus (Australian echidna): 119946061
Entry
119946061         CDS       T10703                                 
Symbol
MAP2K1
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 1
  KO
K04368  mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
Organism
tacu  Tachyglossus aculeatus (Australian echidna)
Pathway
tacu01521  EGFR tyrosine kinase inhibitor resistance
tacu01522  Endocrine resistance
tacu04010  MAPK signaling pathway
tacu04012  ErbB signaling pathway
tacu04014  Ras signaling pathway
tacu04015  Rap1 signaling pathway
tacu04022  cGMP-PKG signaling pathway
tacu04024  cAMP signaling pathway
tacu04062  Chemokine signaling pathway
tacu04066  HIF-1 signaling pathway
tacu04068  FoxO signaling pathway
tacu04071  Sphingolipid signaling pathway
tacu04072  Phospholipase D signaling pathway
tacu04114  Oocyte meiosis
tacu04140  Autophagy - animal
tacu04148  Efferocytosis
tacu04150  mTOR signaling pathway
tacu04151  PI3K-Akt signaling pathway
tacu04210  Apoptosis
tacu04218  Cellular senescence
tacu04270  Vascular smooth muscle contraction
tacu04370  VEGF signaling pathway
tacu04371  Apelin signaling pathway
tacu04380  Osteoclast differentiation
tacu04510  Focal adhesion
tacu04540  Gap junction
tacu04550  Signaling pathways regulating pluripotency of stem cells
tacu04613  Neutrophil extracellular trap formation
tacu04620  Toll-like receptor signaling pathway
tacu04650  Natural killer cell mediated cytotoxicity
tacu04660  T cell receptor signaling pathway
tacu04662  B cell receptor signaling pathway
tacu04664  Fc epsilon RI signaling pathway
tacu04666  Fc gamma R-mediated phagocytosis
tacu04668  TNF signaling pathway
tacu04720  Long-term potentiation
tacu04722  Neurotrophin signaling pathway
tacu04725  Cholinergic synapse
tacu04726  Serotonergic synapse
tacu04730  Long-term depression
tacu04810  Regulation of actin cytoskeleton
tacu04910  Insulin signaling pathway
tacu04912  GnRH signaling pathway
tacu04914  Progesterone-mediated oocyte maturation
tacu04915  Estrogen signaling pathway
tacu04916  Melanogenesis
tacu04917  Prolactin signaling pathway
tacu04919  Thyroid hormone signaling pathway
tacu04921  Oxytocin signaling pathway
tacu04926  Relaxin signaling pathway
tacu04928  Parathyroid hormone synthesis, secretion and action
tacu04929  GnRH secretion
tacu04934  Cushing syndrome
tacu04935  Growth hormone synthesis, secretion and action
tacu05010  Alzheimer disease
tacu05022  Pathways of neurodegeneration - multiple diseases
tacu05034  Alcoholism
tacu05132  Salmonella infection
tacu05135  Yersinia infection
tacu05160  Hepatitis C
tacu05161  Hepatitis B
tacu05163  Human cytomegalovirus infection
tacu05164  Influenza A
tacu05165  Human papillomavirus infection
tacu05166  Human T-cell leukemia virus 1 infection
tacu05167  Kaposi sarcoma-associated herpesvirus infection
tacu05170  Human immunodeficiency virus 1 infection
tacu05200  Pathways in cancer
tacu05205  Proteoglycans in cancer
tacu05206  MicroRNAs in cancer
tacu05207  Chemical carcinogenesis - receptor activation
tacu05208  Chemical carcinogenesis - reactive oxygen species
tacu05210  Colorectal cancer
tacu05211  Renal cell carcinoma
tacu05212  Pancreatic cancer
tacu05213  Endometrial cancer
tacu05214  Glioma
tacu05215  Prostate cancer
tacu05216  Thyroid cancer
tacu05218  Melanoma
tacu05219  Bladder cancer
tacu05220  Chronic myeloid leukemia
tacu05221  Acute myeloid leukemia
tacu05223  Non-small cell lung cancer
tacu05224  Breast cancer
tacu05225  Hepatocellular carcinoma
tacu05226  Gastric cancer
tacu05230  Central carbon metabolism in cancer
tacu05231  Choline metabolism in cancer
tacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
Enzymes [BR:tacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     119946061 (MAP2K1)
Protein kinases [BR:tacu01001]
 Serine/threonine kinases: STE group
  STE7 family
   119946061 (MAP2K1)
SSDB
Other DBs
NCBI-GeneID: 119946061
NCBI-ProteinID: XP_038623369
LinkDB
Position
26:8280117..8358739
AA seq 395 aa
MPMPRKKPDPIQLNPTPDGAAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQ
KVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLIMARKLIHLEIKPAIRNQIIRELQVL
HECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLT
YLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGT
HYSVQSDIWSMGLSLVEMAIGRYPIPPPDSKELELMFGCTVEGDASETSPRQRTPGRPIS
SYGLDNRPPMAIFELLDYIVNEPPPKLPNGVFSLEFQDFVNKCLIKNPAERADLKQLMVH
TFIKRAEAEDVDFAGWLCSTIGLNQPSTPTHAAGV
NT seq 1188 nt   +upstreamnt  +downstreamnt
atgcccatgcccaggaagaagcccgaccccatccagctcaaccccaccccggacggggcc
gccgtcaacgggaccagctccgccgagaccaacctggaagcgctccagaagaagctggaa
gaactggagctggacgagcagcagcgcaaacgactggaggctttcctcacccagaaacag
aaagtcggggaactcaaggatgacgacttcgagaaaatcagcgagctgggagccgggaac
ggcggggtggtgttcaaagtctcccacaagccctctgggctcatcatggcccgaaagctc
atccacctagagatcaagccggccatccggaaccagatcatccgggagctgcaggtgctc
catgaatgcaactccccgtacatcgtcggcttctacggggccttctacagtgacggcgag
atcagcatctgcatggagcatatggatggtgggtccttggatcaggtcctgaagaaagcc
ggtagaattccagagcagattctgggcaaagttagcatcgctgtaataaaaggtctaacg
tatctgagggagaaacataaaattatgcacagagacgtgaagccgtccaacatcttggtg
aactcccgcggtgagatcaagctctgcgatttcggggtcagcgggcaactgatcgactcc
atggccaactcctttgtgggcacgaggtcctacatgtcgccggagagactacaaggtact
cattattcagtgcagtctgacatctggagcatgggcttatctttggtggagatggctatt
ggtaggtacccgatccctcctcccgattccaaggagctggaactgatgttcggatgcacg
gtggagggagacgcttcggagacgtcgcctcgacagcggaccccagggaggcccattagc
tcttacggcctggacaacagaccccccatggccatctttgaactgctggactacatcgtc
aacgagccgccacccaaactgcccaatggagtcttcagtcttgagtttcaagactttgtg
aataaatgcctcatcaaaaacccggctgagagagccgacctgaagcaactcatggttcac
actttcatcaagagagccgaggcggaggacgtggactttgcgggctggctctgctccacg
ataggcctgaaccagcccagcacgcccacccacgccgccggagtctaa

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